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Amazon receives FDA warning letter for supplements with undeclared ingredients

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Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#121

It’s been common knowledge that any Chinese ED supplement on Amazon that is effective has Viagra in it. This is not a bug but a feature

> It’s been common knowledge that any Chinese ED supplement on Amazon that is effective has Viagra in it. This is not a bug but a feature And who knows what else!!! I'd never ingest anything that has Chinese provenance. Chinese garlic comes to mind as the latest thing to try to avoid. Not sure if true but it seems to be grown in sewage. I'd rather be safe and avoid that altogether.

A lot of the garlic in yhe US is from China, so if you ate in a restaurant you likely had some already.

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#122

Most supplements are garbage. Since they don't actually work, most people would never know if you replaced their magnesium or calcium supplement with chalk. Some supplements do work, but since they're not regulated, they're drowned out by nonsense and noise. OK, so you don't want to be a rube?...you do your research and then piece of shit fitness influencers tell you "ohh...that vitamin you bought form Walgreens or C…

>Now that I'm over 40, I do everything right (daily exercise, eat healthy, get sleep, etc) and still feel like shit most of the day....same with most my age... I’m nearing 40. Are you sure it’s normal to feel terrible most of the day when eating right, exercising, and getting enough sleep? This doesn’t sound normal to me.

I'm 45, walk, weight lift, eat well, sleep well, and feel better than I ever have. My dad says he didn't start to "feel" his age until 80: it may just be genetics?

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#123
post #65

I think with the state of things, Amazon should be completely banned from selling anything that might be construed a supplement. They have such lax controls that your protein powder or vitamin pills might contain pretty much anything. Even reputable brands bought from their brand storefront might be counterfeit [1]. You’d be shocked at the number of things that are counterfeit. A friend of mine recently bought a nich…

Calling for Amazon to be banned from selling supplements is extreme, IMO. But they should be accountable for preventing counterfeit items from being sold or marketed as the items they’re counterfeiting. In cases where the authenticity of the item has not been verified, that should be made clear to the buyer. Absence of such an indicator would mean the product is authentic (consumers should IMO be able to rely on prod…

> Calling for Amazon to be banned from selling supplements is extreme

If a physical store near you sold fake everything, including supplements, you’d think it extreme to shut it down?

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#124
post #41

Earlier quoted context omitted.

If we’re going to have an honest conversation, Sildenafil does have some serious potential side effects and contraindications. Googling “why does viagra require a prescription?” I get an answer attributed to Healthline: “due to these severe (but rare) side-effects, Viagra requires a prescription”. At least acknowledge that, it is a good reason. A doc visit does take time but it neither takes 2 hours nor costs $100 fo…

> maybe the minor hurdle of having to require a doc to check on the potential for side-effects really is justified? Viagra is trivially available on the black market because many people don’t want to put up with that B.S. Antibiotics have a public interest in being gatekept; they harm everyone if abused. A similar argument can be made for addictive substances. Merely-harmful drugs, on the other hand, can be disclaime…

How, in your view, does dilution change the therapeutic index of a chemical? If a drug is effective at 20 milligrams, but at 60 milligrams has a steep rise in the incidence of hypotension, how does taking that same 60 milligrams in a larger volume of filler (e.g. water, or spread across more physical pills) change the fact that you've just taken 60 milligrams?

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#125

I think with the state of things, Amazon should be completely banned from selling anything that might be construed a supplement. They have such lax controls that your protein powder or vitamin pills might contain pretty much anything. Even reputable brands bought from their brand storefront might be counterfeit [1]. You’d be shocked at the number of things that are counterfeit. A friend of mine recently bought a nich…

> Amazon needs to stop co-mingling inventory That alone would solve 99% of the problems, as dedicated inventory would allow to quickly weed out the bad actors.

My understanding is that co-mingling was originally a distribution optimization. I can’t remember if I was there under the initial rollout or they had tried it, stopped it, and rolled it out again during my tenure, but when I started in 2009 it wasn’t a thing, and people were opinionated about why it wasn’t a thing (to protect seller reputation), but it was obvious how it could reduce shipping times (if you have your inventory on the west coast, but a buyer on the east coast, picking from another merchant reduces shipping time and cost and wasted warehouse space partitioning everyone’s inventory).

However, Amazon has abandoned any idea of consistent reliable shipping or even delivery “promises”, so the only thing co-mingling does is reduce shipping costs and warehouse space at the customer’s expense. That’s the antithesis of what Amazon delivery used to be. It’s sad to see all the work we did on Prime and Delivery Experience get washed down the drain. Prime used to be a no brained for anyone who used Amazon regularly, and now I’m not even sure if there is discrete value there anymore, rather than just a mishmash of unrelated, mediocre up upsell opportunities.

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#126
Looks like a lot of uninformed opinions in here.

As someone who has made a career consulting for supplement companies selling on Amazon, this does not surprise me. When Amazon first instituted testing requirements for supplements (something that already exists under federal law) they required all sellers to provide testing for all of their products. Failure to do so resulted in removal of your products from the marketplace.

Since then, two things have changed. Certain supplement categories have additional testing requirements outside of what is expected by the FDA. Companies have to prove the absence of certain illegal ingredients. But, Amazon has switched to random testing requirements. In the last 3 years, Amazon has not asked a single one of my clients to provide any COAs. I have seen other brands have to provide some, but the requirements are very limited. It is for this reason, unsurprising that illegal products are making it into customer hands.

It is my understanding that the individual who drove the campaign to get COAs, GMP certificates, etc for all supplement listings is no longer with Amazon, and nobody has filled that role since. That should be changed.

But Amazon has always been aggressive over enforcement of marketing claims, and some claims will always instantly flag a COA requirement. Sellers use careful wording to avoid these flags. The solution is to make a COA required for the creation of these listings.

I mean, let's take this one further. Most supplement companies are just marketing companies. They don't formulate the product, they don't manufacture the ingredients, and they don't even blend the powder. They make a brand. But, the FDA doesn't care. As a brand receiving product from a manufacturer, you are still required to test it. The manufacturer is also required to test the raw materials as well as the finished product. Yet, most companies I speak to are not testing product received. They rely solely on the manufacturer testing.

So we should be requiring these brands to do their due diligence. Show me the COA you are supposed to have for every lot you send in. It's already required by the FDA.

As is always the case with supplements, regulation is not the issue. It's enforcement

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#127
It is great that the FDA does these random checks and can identify supplement and food items that contained erectile dysfunction drugs in them. It is a tough call to try and completely eliminate such products from all the marketplaces, especially when some approved US drugs may be not controlled in other countries. I’d trust Amazon as more able to do so than a random pharmacy or internet store. Let’s see how this story develops.

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#128
post #16

Heard a talk once by someone that managed nutrition for an NFL team. She said periodically clusters of players would pop positive for meth and inevitably it would be some new supplement that was giving them results and they told all their teammates about it. They’d just tell them to quit using it and move on. Interesting story, possibly true.

Any even remotely WADA compliant drug testing uses chromatography, this story is most likely false.

The (intentional or unintentional) contamination of dietary supplements with performance-enhancing drugs is a widespread problem.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691710/

https://www.frontiersin.org/articles/10.3389/fspor.2022.8682...

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#129

I had the opportunity to get a peek at the FDA database of adulterated supplements and by far the most common type of adulteration was people spiking with viagra. I asked why and was told: “Man has been searching for an aphrodisiac for thousands of years and we finally found it. Of course they are going to put it in everything!”

The product reviews would be interesting to read.

Re: Amazon receives FDA warning letter for supplements with undeclared ingredients

#130

I purchased a vitamin c supplement that was pure white and odorless/tasteless. I posted a review and photos. Obviously fake filler of some sort, Amazon removed my review as inaccurate when it's obvious whatever was in those capsules was not ascorbic acid of any kind. They also claimed to have zinc (greenish) and elderberry (purple). It's not safe for Amazon to let any random exporter put stuff for sale without any sa…

When I reviewed a product as obviously fake they also removed my review. The company as a whole really kind of disgusts me now.

yeah they are kind of the last resort for me at this point when buying online.
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