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Injection of "smart insulin" regulates blood glucose levels for one week

arstechnica.com

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Re: Injection of "smart insulin" regulates blood glucose levels for one week

#32

Earlier quoted context omitted.

Guess people can visit Canada or Mexico weekly

It is against US law to bring insulin back from Mexico. People still smuggle in a little, but there are penalties if they get caught with a lot of insulin. I live in Texas, about 12 hours from the Mexican border, so it's not worth the trip.

Probably does not count for weekly shots administered on the other side of the border

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#33

I have "type 1" diabetes for 27 years. I hear similar stories like this (revolutionary cure working on animal models) every year or two. Until now non of them worked. I hope this one will be beeter but my expectations are quite low.

"Just another 5 years for a cure"

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#34
post #24

Earlier quoted context omitted.

A box of Fiasp or Levemir insulin costs $477-$560. The better insulins cost more. If I give myself the $24.88 WalMart insulin, I can not eat lunch at my regular time and then have to eat in the middle if class. (Assuming I had a high blood sugar reading going into lunch and gave myself R an hour before lunch.) If I can afford the Fiasp, I can go ahead and eat at my regular time. It's just expensive.

This is a weird objection because if the expensive insulin did not exist (effective price = $inf) it would not apply.

This is not a weird objection. The companies distributing the "expensive insulin" also distribute the affordable insulin, and created the cost disparity. Something strikingly apparent to anyone interacting with insurance companies for any chronic condition.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#35
There is also what Sigilon (now Eli Lilly) is doing, which is to encapsulate living cells in a matrix they cannot escape. The cells sense glucose levels and secrete appropriate levels of insulin locally. In the current iteration I think the millimeter sized beads are injected in the peritoneum, and are removable.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#36

I have "type 1" diabetes for 27 years. I hear similar stories like this (revolutionary cure working on animal models) every year or two. Until now non of them worked. I hope this one will be beeter but my expectations are quite low.

"Just another 5 years for a cure"

Fusion within our reach.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#37
post #24

Earlier quoted context omitted.

A box of Fiasp or Levemir insulin costs $477-$560. The better insulins cost more. If I give myself the $24.88 WalMart insulin, I can not eat lunch at my regular time and then have to eat in the middle if class. (Assuming I had a high blood sugar reading going into lunch and gave myself R an hour before lunch.) If I can afford the Fiasp, I can go ahead and eat at my regular time. It's just expensive.

This is a weird objection because if the expensive insulin did not exist (effective price = $inf) it would not apply.

My concern is that I need to live a fairly normal life, and I need to work. If I can not eat lunch at a normal time at work, and if I have to get up every 2 or 3 hours all night long to deal with my diabetes, then I can not work a normal job.
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