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Injection of "smart insulin" regulates blood glucose levels for one week

arstechnica.com

11–20 of 37 posts

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#12

So if regular insulin is already overpriced, how overpriced will this medication be?

From the article, this is a small animal study involving less than 10 animals, no one knows if this even works in humans or if the benefits seen here will translate into a larger study.

This is so far from being a commercial product that asking about costs means nothing.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#14

So if regular insulin is already overpriced, how overpriced will this medication be?

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#15

So if regular insulin is already overpriced, how overpriced will this medication be?

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

if this is true, do you know the source of the meme that insulin is extremely expensive for uninsured people in the US?

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#16

Earlier quoted context omitted.

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

if this is true, do you know the source of the meme that insulin is extremely expensive for uninsured people in the US?

[deleted]

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#17

Earlier quoted context omitted.

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

if this is true, do you know the source of the meme that insulin is extremely expensive for uninsured people in the US?

There are different types of insulin (short acting, long acting) and the cheapest version isn't always best for a specific person depending on their individual situation. If you want more information on the structural factors of the unaffordability of insulin this article could help: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597930/

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#18

Earlier quoted context omitted.

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

if this is true, do you know the source of the meme that insulin is extremely expensive for uninsured people in the US?

They lowered the price at some point in the few years, at least on some versions.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#19
post #10

Earlier quoted context omitted.

I'm a type 2 diabetic. My diabetes was not caused by diet. My diabetes is caused by failure of my pancreas to produce the necessary cells for insulin production, and insulin resistance of cells within my body. Not everyone who has diabetes acquired it from bad diet. Perhaps learn some empathy njroute22, because your comment was hurtful and demeaning.

That sounds like Type 1 diabetes. Your pancreas doesn't generate insulin in Type 1, and in type 2 your body has insulin resistance, which makes the insulin that your body makes ineffective at regulating your blood sugar.

Type 2 diabetes is not a single disease, but rather a combination of failed signaling pathways in a variety of tissue.

For some people, they will have insulin resistance in fat cells, so lipolysis continues even during high insulin levels.

Some people will have hepatic insulin resistance so their liver does not uptake glucose as glycogen as readily or inhibit gluconeogenesis.

Some people will have insulin resistance in the pancreatic alpha cells, so glucagon production continues in the presence of insulin.

Some people will have skeletal muscle tissue insulin resistance, where excess glucose is not as readily taken up by skeletal muscle tissue (our most metabolic active tissue).

Some people can also have insulin resistance along side decreased insulin production in the pancreatic beta cells. This is mixed type 1 and type 2.

Re: Injection of "smart insulin" regulates blood glucose levels for one week

#20

Earlier quoted context omitted.

Insulin is available at Walmart for about $25. The newer analog versions cost around $80. It's just private label Novo Nordisk, so all high quality.

if this is true, do you know the source of the meme that insulin is extremely expensive for uninsured people in the US?

A box of Fiasp or Levemir insulin costs $477-$560.

The better insulins cost more.

If I give myself the $24.88 WalMart insulin, I can not eat lunch at my regular time and then have to eat in the middle if class. (Assuming I had a high blood sugar reading going into lunch and gave myself R an hour before lunch.)

If I can afford the Fiasp, I can go ahead and eat at my regular time. It's just expensive.

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