51–60 of 91 posts
Great! Now I can sequence the dna of women I’m creepily interested in, coworkers, bosses, and any celebrities i can manage to get a sample from by pouring thru their trash at 2am. Thanks, Nebula!
If you have a publicly available photo of yourself (e.g. public social media), it's possible to match that to your genomic sequence. I.e. you already have to be anonymous online to have a chance that a private company cannot reidentify you. https://www.science.org/doi/10.1126/sciadv.abg3296
Seems like the technique only works in highly controlled scenarios (e.g. you have tens of phenotypes and images and want to have a better than random chance of assigning one to the other): > Nevertheless, re-identification risk in the wild does not appear to be especially high. While we observe a success rate as high as 25%, this is only achieved when the genomic dataset is extremely small, on the order of 10 individ…
I find this fascinating. I once was considering getting my whole genome sequenced from Nebula but then I realized that their sequencing was being done by Beijing Genomics Institute (BGI). The quality of sequencing from BGI is very high, but the reality is it has some fairly established ties to the PLA (to the extent that it's considered for sanctions by lawmakers). There's been concern in the bioinformatics community…
Earlier quoted context omitted.
I did the same thing. Have you found any software to analyze it?
It's all command line tools, one is called samtools and another is called picard, there might be another one I'm forgetting. The interesting this with the data is that it isn't your raw genome, it's the entire data from all the sequencing runs of 30 or whatever base pairs (I got my scan done at the 30x level which is supposed to mean that on average every base pair is read 30 times). So it's not like you can just rea…
Earlier quoted context omitted.
I did the same thing. Have you found any software to analyze it?
It's all command line tools, one is called samtools and another is called picard, there might be another one I'm forgetting. The interesting this with the data is that it isn't your raw genome, it's the entire data from all the sequencing runs of 30 or whatever base pairs (I got my scan done at the 30x level which is supposed to mean that on average every base pair is read 30 times). So it's not like you can just rea…
[0]: https://sequencing.com/ [1]: https://sequencing.com/our-difference/privacy-forever
When I signed up for 23andme many years ago, it was via a friend in another country, who re-mailed it for me under a fake name and paid in cash. For some time I would log in through a locale-specific 23andme sub-domain until they eventually merged it all together. It wasn't long before they figured out who I was and placed me within my family tree. My fake name now lives among near and distant relatives I was not awa…
There's nothing logically impossible about such a service, and I'd trust it modulo actual red flags. Too bad afaik nobody's offering it. Once they're archiving their copy I just don't see how they can credibly promise privacy in the longer term.
Last I looked it didn't seem really practical to just buy your own sequencer.
Genome sequencing has become so cheap in recent years (and will be much cheaper in the next few years) that everyone who wants it will simply get it. Against the background of personalized medicine, this is also very useful. (My background: CEO of a company for personalized cancer therapy through WGS)
https://www.bundesgesundheitsministerium.de/en/en/internatio...