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A genetically modified bacterium that outcompetes bacteria causing tooth decay

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Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#41

I use a similar product, LEF Florassist Oral https://www.lifeextension.com/vitamins-supplements/item02120... That has BLIS M18™ and Immuno-LP20® BLIS M18: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012604/ I have not noticed any difference.

Does this help with morning breath?

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#43
post #38

Swap spit/kiss someone who gets this. Cheaper than dental insurance. Time to bring back the kissing booth.

If this is true and approved it will probably be sold over the counter. Similar to how you buy yoghurt or probiotic pills today.

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#44
post #32

I'd want to know a lot more about that antibiotic these bacteria produce. If there is no natural immunity it will be developed very shortly if doses produced are low (and how can they possibly control for the dose). Then on the other hand if doses are really high, what about consuming an antibiotic for the rest of your life? What will it do to your gut flora? It seems very implausible to me. If I was working for FDA…

This is already answered in TFA:

> 3: Is it dangerous to have bacteria secreting an antibiotic in your mouth? Does this mean you’re on a weak antibiotic all the time?

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#45

I've just started using ProBiora3 to try to reduce my gingivitis levels. I would love a one-application solution and will be watching this closely.

My understanding is that bacteria that cause gingivitis thrive in a different pH level than the ones that cause cavities. I have no cavities but I am in a constant battle with gum disease. I don't think this specific strain will help us, but it can obviously lead the way.

Has ProBiora3 helped?

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#46
Anecdote time: My great grandmother lived to be 102 and never had a cavity. Kept all her teeth to the end.

One time, an orderly who thought she was just being senile tried to reach into her mouth to take out her teeth (thinking she had dentures). My great grandmother bit that person; hope they learned not all old people are senile!

I’m 40% of the way there. No cavities and rave reviews from my dentist. I brush—-best case —-once a day.

I’d not be surprised if it’s a genetic lottery of tooth enamel, tooth size (small) and mouth biome.

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#47

Earlier quoted context omitted.

I trust the sceince just fine, i dont trust corporate interests and how heavily and deeply coporate rot has penetrated into our institutions. I activly expect dishonesty on the part of corporate interest, and corporate interest is increasingly if not already entierly, government interest.

And yet, modern science involves humans, human interests, and human failings. Science practice is as flawed as the people that do it.

Yes, but the pay is shit, the social recognition is non existent, etc. So its not going to attract as many of the dark triad types like law or upper managment would.

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#48

This story has been around for far too long and evidence is unbelievably weak, and the claims border on fraudulent. 1. The claim that this strain outcompetes the same S mutans from occupying the same niche cannot be true unless this strain is also capable of creating and tolerating environments with low pH. By definition if it creates acid to the same degree it will also cause cavities. 2. Single applications are ins…

FTA, the process is: blast mouth with oral antibiotics then swab the stuff on.

It'll be interesting to see if it works.

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#49

Anecdote time: My great grandmother lived to be 102 and never had a cavity. Kept all her teeth to the end. One time, an orderly who thought she was just being senile tried to reach into her mouth to take out her teeth (thinking she had dentures). My great grandmother bit that person; hope they learned not all old people are senile! I’m 40% of the way there. No cavities and rave reviews from my dentist. I brush—-best…

What is your diet ? I am assuminf there is no processed sugar or refined wheat/gluten ?

Re: A genetically modified bacterium that outcompetes bacteria causing tooth decay

#50

Anecdote time: My great grandmother lived to be 102 and never had a cavity. Kept all her teeth to the end. One time, an orderly who thought she was just being senile tried to reach into her mouth to take out her teeth (thinking she had dentures). My great grandmother bit that person; hope they learned not all old people are senile! I’m 40% of the way there. No cavities and rave reviews from my dentist. I brush—-best…

How's your breath? Frequently you either have a mouth microbiome that ends up acidic and prone to cavities, or you end up with a high pH mouth which lends itself to tartar buildup and halitosis.

Of course if your teeth are decaying due to cavities and this is left untreated, halitosis is also a common result.

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