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Taking low-dose aspirin is associated with 20% reduction in cancer deaths

cardiff.ac.uk

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Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#21

Post by nomel »

objektif wrote: post #13
01100011 wrote: post #11

Earlier quoted context omitted.

Increases risk for hemorrhagic strokes as well. AFAIUI, your clotting ability is impaired, so if you get a minor bleed, it's not minor for long. IIRC, the recommendations to folks taking aspirin for heart attack prevention is "don't, unless you've already had an ischemic event" because the risk outweighs the benefits for everyone else. That could change if we find new and/or unexpected benefits from low-dose aspirin.

I am very skeptical about these side effect claims. Do you have hard data supporting this or doctor hearsay. Years ago I remember watching Charlie Rose Brain series where one of the professors said something like “ we know of two drugs that we are certain are very safe for human beings: alcohol and aspirin.”

Aspirin's bleeding risk is very well studied. You can find many papers showing between around 30% increase in the brain, and around 60% for the gut.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#22

Post by softwaredoug »

8f2ab37a-ed6c wrote: post #10

Now combine that with extra fiber and you'll practically live forever: https://news.ycombinator.com/item?id=38523805

And fewer calories…

And time restricted feeding (ie 8/16 intermittent fasting)

https://www.nature.com/articles/s41392-022-01163-z

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#23

Post by InSteady »

rgrieselhuber wrote: post #4
didntknowya wrote: post #2

although indiscriminate long term aspiring can cause GI side effects

I've heard it's good to take with milk.

Common misconception, it's actually best to take with alcoholic beverages containing dairy. So like a white Russian.

(I'm obviously joking, this is your friendly reminder not to take medical advice from randos on the internet, especially when their source is "I've heard").

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#24

Post by pinko »

objektif wrote: post #13
01100011 wrote: post #11

Earlier quoted context omitted.

Increases risk for hemorrhagic strokes as well. AFAIUI, your clotting ability is impaired, so if you get a minor bleed, it's not minor for long. IIRC, the recommendations to folks taking aspirin for heart attack prevention is "don't, unless you've already had an ischemic event" because the risk outweighs the benefits for everyone else. That could change if we find new and/or unexpected benefits from low-dose aspirin.

I am very skeptical about these side effect claims. Do you have hard data supporting this or doctor hearsay. Years ago I remember watching Charlie Rose Brain series where one of the professors said something like “ we know of two drugs that we are certain are very safe for human beings: alcohol and aspirin.”

Anecdata: even a few days of low-dose aspirin causes me terrible GI pain and exacerbates an otherwise 30-year dormant ulcer. I would love to be able to take it, but I can't tolerate it at all.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#25

Post by smt88 »

dhuk_2018 wrote: post #7

Tomorrow's news will say it will be a 20% increase in some other desease...

Aspirin is anti-inflammatory. A huge number of illnesses are caused or worsened by inflammation. Aspirin is likely to show benefit for a huge variety of conditions.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#28

Post by Obscurity4340 »

InSteady wrote: post #23
rgrieselhuber wrote: post #4

Earlier quoted context omitted.

I've heard it's good to take with milk.

Common misconception, it's actually best to take with alcoholic beverages containing dairy. So like a white Russian. (I'm obviously joking, this is your friendly reminder not to take medical advice from randos on the internet, especially when their source is "I've heard").

I did hear something from a stranger about hearing somethings on internet from strangers so this tracks, it would seem. I will comply fully henceforth!

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#29

Post by stvltvs »

InSteady wrote: post #14
sdenton4 wrote: post #8

Earlier quoted context omitted.

Also addressed in TFA, it turns out. GI symptoms are pretty mild in the universe of cancer drug side effects, and the aspirin slows metastatic cancer spread considerably, so seems like a no brainer.

It isn't a cancer drug, so that isn't a fair comparison. GI symptoms from eating more broccoli and not ever drinking are also pretty mild compared to cancer drugs. Aspirin appears to be a preventative according to some initial research. National cancer institute says even the most at-risk age group (age 60+) is still only has cancer rates of around 1 in 100. How long are you going to take low dose aspirin? Are GI sym…

The study population was cancer patients, so low dose aspirin was studied as a cancer drug. It doesn't say what the effect would be in the general population. Don't take aspirin just because it might help cancer patients, but if you've had cancer, consult with your oncologist.

Re: Taking low-dose aspirin is associated with 20% reduction in cancer deaths

#30

Post by _yb2s »

objektif wrote: post #13
01100011 wrote: post #11

Earlier quoted context omitted.

Increases risk for hemorrhagic strokes as well. AFAIUI, your clotting ability is impaired, so if you get a minor bleed, it's not minor for long. IIRC, the recommendations to folks taking aspirin for heart attack prevention is "don't, unless you've already had an ischemic event" because the risk outweighs the benefits for everyone else. That could change if we find new and/or unexpected benefits from low-dose aspirin.

I am very skeptical about these side effect claims. Do you have hard data supporting this or doctor hearsay. Years ago I remember watching Charlie Rose Brain series where one of the professors said something like “ we know of two drugs that we are certain are very safe for human beings: alcohol and aspirin.”

Those are both drugs with very significant risks
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