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Nicotine (2016)

gwern.net

21–30 of 273 posts

Re: Nicotine (2016)

#21

[flagged]

Alas, it's not always about what you care. It'd be way too useful to treat this platform as an exploratory tool, and enjoy contents of different variety as opposed to what you expect. This would help expand your horizons and add new dimensions to your knowledge.

Re: Nicotine (2016)

#22

Earlier quoted context omitted.

No, I mean nicotine as I clearly indicated in my comment. It's not harmless and its ridiculous to think a drug that constricts the vessels and blood flow in your body would be so.

Like caffeine?

Good thing I don't drink coffee.

Re: Nicotine (2016)

#23
post #17

I'm concerned that many might miss the nuance and subtlety of the main issue: - Nicotine IS really addictive when distributed through common uses (smoking, vaping). Yes, if the absorption is progressive and in small dosages, the addiction is less severe, but this is not useful for smokers who want to quit and presents a dangerous introduction for others

100% correct. This article circulates every so often but it's basically just super dangerous. Recommend just looking at NIH [0] here. [0]: https://duckduckgo.com/?q=nicotine+site%3Awww.ncbi.nlm.nih.g...

Could you provide something way more specific than a DDG search?

Re: Nicotine (2016)

#24

[flagged]

Even though I personally wouldn’t agree with them, I could understand why someone might think that nicotine or cannabis stuff isn’t relevant to this site, but how is Internet regulation stuff not?

Re: Nicotine (2016)

#25

Earlier quoted context omitted.

No, I mean nicotine as I clearly indicated in my comment. It's not harmless and its ridiculous to think a drug that constricts the vessels and blood flow in your body would be so.

Like caffeine?

Is that a counterpoint? Pointing to something unrelated from the conversation. Maybe both arnt great for you?

Re: Nicotine (2016)

#26

Earlier quoted context omitted.

You mean smoking is terrible for you. As the cited studies indicate, nicotine itself (delivered by patched / gum) is fairly harmless. Not completely risk free, but nothing at all like smoking.

No, I mean nicotine as I clearly indicated in my comment. It's not harmless and its ridiculous to think a drug that constricts the vessels and blood flow in your body would be so.

> It's not harmless and its ridiculous to think a drug that constricts the vessels and blood flow in your body would be so.

Why? Because it increases blood pressure?

That's a problem if it's chronic and severe, afaik a milk vasoconstrictive effect isn't going to kill you.

Re: Nicotine (2016)

#27

Nicotine is just terrible for you. Smoking is linked to alzheimers and I watched my grandfather smoke his pipe and decline cognitively with that disease. Im not sure if its only proven from the toxins in smoke or the nicotine but I would assume constricting the blood vessels (with nicotine) leads to plaque buildup in the body and brain. Because of the vessel constriction is stops healing in the body as well all the w…

You mean smoking is terrible for you. As the cited studies indicate, nicotine itself (delivered by patched / gum) is fairly harmless. Not completely risk free, but nothing at all like smoking.

There's some studies suggesting nordic Snus (like all natural chew w/o chemicals added) is fairly harmless. Anecdotally I've read people highly addicted to it, so very suspicious of any claim that nicotine itself isn't addictive and just smoking is.

Re: Nicotine (2016)

#28
Nicotine is a stimulant but weirdly enough, it has always improved my sleep (even when taken close to sleep). I never really understood why.

Re: Nicotine (2016)

#29
post #14

Earlier quoted context omitted.

The article wasn’t talking about smoking, and nicotine is not addictive.

https://en.wikipedia.org/wiki/Nicotine > Nicotine is highly addictive. https://nida.nih.gov/publications/research-reports/tobacco-n... > Is nicotine addictive? Yes. --- If nicotine wasn't addictive, why would people find that nicotine patches or nicotine gum helps with withdrawals from various tobacco products?

Addiction is complex. Folks are generally addicted to a combination of things. For example they’ll do a particular drug, sit in a particular environment, with or without a social element, with or without food. Utilizing one of the elements without the others helps break the association. Its the same thing on a smaller level.

Re: Nicotine (2016)

#30

Earlier quoted context omitted.

Nicotine not addictive? That’s a bold claim.

The article cites some fairly convincing studies that the addictiveness is from tobacco’s other (non-nicotine) chemicals including MAOIs. Is smoking addictive? Absolutely, but not because it contains nicotine.

The articles seems much more inconclusive than your comment implies. On one hand, yes, they point out that MAOIs may be confounding. But they also say:

“additional work since 2002 has clearly shown that nicotine alone does have some addictive properties”

And, frustratingly, they point out that addiction effects can’t be parsed out using smokers because of the confounding effects of other chemicals present in tobacco yet they quote a study using smokers to support the non-addiction claim.

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