It's funny thinking back to the hype cycle of Itanium back in the heady days where performance was doubling every year, desktop was king and this was the future . Turns out it was more like IBM's MCA / PS2 rather than the future. Compatibility and ubiquity wins. As nearly always.
It was quite a bit worse than that. If you ignore the horror of IBM vendor lock-in, which in retrospect made the whole thing untenable, and the overpriced nature of the systems, MCA was a fine thing for its time. The PS/2s had some nice features. They were compatible with everyone's DOS and Windows stuff, even if IBM would have preferred you use OS/2, and so on.
Itanium was a piece of crap, even if you could somehow ignore the cost and lock-in.