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One sleepless night can rapidly reverse depression for several days in mice

news.northwestern.edu

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Re: One sleepless night can rapidly reverse depression for several days in mice

#71

Post by Obscurity4340 »

nehal3m wrote: post #28
catchnear4321 wrote: post #18

Earlier quoted context omitted.

plenty of people force themselves to stay up all night once in a blue moon for mental health reasons, all without blogging about it.

Really, this is a thing? I’ve never heard about it. I used to stay up late sometimes when I was younger, but that was because the world went to sleep and I felt at peace doing my own thing. It wasn’t because I was trying to feel better the next day, in fact it tended to screw the next day up.

There's something to it. Also with dissociatives. Something about these substances or practices can help "reset" you like pulling the plug on an electrical device and forcing it to reboot with refreshed state

Re: One sleepless night can rapidly reverse depression for several days in mice

#72

Post by hotnfresh »

Waterluvian wrote: post #45
Hard_Space wrote: post #35

Having suffered from severe depression for over forty years, this reminds me of when I was 17, 18, etc. and suddenly discovered that if I stayed up for two days, the problem went away. So I knew this a very long time ago; but it always seemed to me that, besides smoking, this was just about one of the worst habits you could develop. By my mid-twenties, I had stopped.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

I can get to sleep without it. I just can't be sure I'll be able to get to sleep without it. Like 30%-40% odds I'll have serious sleep trouble if I don't take it, so I take it most nights.

Amazing stuff, much better than the sleeping pill prescription I had years back (Lunesta).

Re: One sleepless night can rapidly reverse depression for several days in mice

#73

Post by 1980phipsi »

Waterluvian wrote: post #45
Hard_Space wrote: post #35

Having suffered from severe depression for over forty years, this reminds me of when I was 17, 18, etc. and suddenly discovered that if I stayed up for two days, the problem went away. So I knew this a very long time ago; but it always seemed to me that, besides smoking, this was just about one of the worst habits you could develop. By my mid-twenties, I had stopped.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

My brother basically needs THC to sleep.

Or strenuous physical activity all day.

Re: One sleepless night can rapidly reverse depression for several days in mice

#74

Post by micromacrofoot »

bobbylarrybobby wrote: post #61
Waterluvian wrote: post #45

Earlier quoted context omitted.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

If you cannot fall asleep without a drug then I'd say the drug has already caused issues

well the issue was not being able to fall asleep without a drug

so falling asleep with a drug is an improvement

Re: One sleepless night can rapidly reverse depression for several days in mice

#75

Post by teaearlgraycold »

bdamm wrote: post #69
Waterluvian wrote: post #45

Earlier quoted context omitted.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

Being unable to sleep is a common withdrawal symptom for cannabis use disorder. Congratulations, you are habituated, and long-term problems are likely accumulating as you are losing out on REM sleep and probably developing emotional and physical conditions related to cannabis use. Good luck!

Yeah. I used to smoke a tiny bit every day and it really fucked me up.

Re: One sleepless night can rapidly reverse depression for several days in mice

#77

Post by m463 »

chupapimunyenyo wrote: post #70

> Chronic sleep loss is well studied, and it’s uniformly detrimental effects are widely documented,” Kozorovitskiy said. I believe he didn't say "it's", he probably said "its".

sort of interesting how your/you're, its/it's, shrimps/softwares and others sort of unconsciously makes what you're reading less authoritative in a 4th wall way.

Re: One sleepless night can rapidly reverse depression for several days in mice

#78

Post by SkyPuncher »

jvm___ wrote: post #52

https://www.reddit.com/r/hangovereffect/ This sub-reddit is dedicated to people who've noticed this effect for ADHD and probably depression as well. Drinking alcohol somehow causes the same 'reversal' of symptoms, either motivation or other mood problems. Lots of discussion as to what causes it - and questions/theories on how to reproduce without alcohol. Alcohol causing sleeplessness, or sleep that's not the usual q…

Shame that I cannot view that without the app

Re: One sleepless night can rapidly reverse depression for several days in mice

#79

Post by Waterluvian »

Loughla wrote: post #60
Waterluvian wrote: post #45

Earlier quoted context omitted.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

So I feel like you exactly identified the long term problem in the same paragraph. I learned years ago that any chemical that helps you sleep ensures that you can't sleep without it. I've used everything from thc to Benadryl to lavender and everything in between. It all had the same effects: slowly degrading effectiveness and sleeplessness without it. Pro-tip: find the source of your insomnia. Is it chemical or is it…

Yeah. I’ve tried. My problem is that 3-4 days of no sleep and I’m just about ready to sign off from this life.

I’ve managed with 5mg THC pills for years. Never had to increase the dosage. I’ve never ever slept well. But back before kids it was easier to just sleep in if I had to.

As best as I can tell, the cause is my adhd or related. My brain will simply. Not. Stop. Racing.

Re: One sleepless night can rapidly reverse depression for several days in mice

#80

Post by johnnyanmac »

bdamm wrote: post #69
Waterluvian wrote: post #45

Earlier quoted context omitted.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

Being unable to sleep is a common withdrawal symptom for cannabis use disorder. Congratulations, you are habituated, and long-term problems are likely accumulating as you are losing out on REM sleep and probably developing emotional and physical conditions related to cannabis use. Good luck!

damn, so I'm screwed and I don't even get to enjoy the upsides of cannabis. Rough world.
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