Waking up in the mornings helps reset my mental state sometimes. I wonder if it's related. If I have an early morning, I usually find that I'm more productive and have more energy to work out or focus on tasks. There's nothing more depressing than a cycle of waking up at 2pm because you stayed up until 5am. Waking up so late makes me feel like I'm wasting my life.
One sleepless night can rapidly reverse depression for several days in mice
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Re: One sleepless night can rapidly reverse depression for several days in mice
#32... in mice.
Are we talking about that small mammal that is a nocturnal species?
Re: One sleepless night can rapidly reverse depression for several days in mice
#33I have a prescription for ketamine and when I take it at night it causes poor sleep and noticeable lethargy the next day. It's not a great thing.
But I think "reversing depression" is codeword for manic and euphoria sensations. It's not targeting the core of what is depression.
Re: One sleepless night can rapidly reverse depression for several days in mice
#34This must be why new parents always seem so bubbly and happy! But seriously, that’s very interesting and explains what I’ve experienced. I’ve been in a depression since quitting my phd a couple months ago and not having a direction in life, but whenever I have trouble sleeping I end up feeling better the next day. Maybe I’ll trying utilizing it to get my portfolio looking better.
There's something about getting 2-3 hours of sleep that makes me feel like I'm on top of the world throughout the day. I've always assumed it was a kind of wild delirium.
The sleep quality is super lossless and actually gainful when you compress it by allowing a slight sleep debt to accrue
Re: One sleepless night can rapidly reverse depression for several days in mice
#35Having suffered from severe depression for over forty years, this reminds me of when I was 17, 18, etc. and suddenly discovered that if I stayed up for two days, the problem went away. So I knew this a very long time ago; but it always seemed to me that, besides smoking, this was just about one of the worst habits you could develop. By my mid-twenties, I had stopped.
Re: One sleepless night can rapidly reverse depression for several days in mice
#36Earlier quoted context omitted.
I noticed something similar (see also: my comment about using magnesium and getting better sleep on the thread about deep sleep yesterday). When I get ~5ish hours of sleep one night a week I am surprisingly more alert the next day but I also crash much harder by night. I cannot sustain multiple days of little sleep but one short night doesn't seem to have such a detrimental effect.
I wonder if this is why ADHD people struggle with sleep.
We have many reasons aha. Always good to start chipping away at the list ;)
Re: One sleepless night can rapidly reverse depression for several days in mice
#37What about all the other studies claiming that poor sleep causes depression? Not sure what to trust these days. Gut tells me poor sleep won't make you ahem "your brain feel slap-happy, loopy and almost giddy" (very scientific).
From the article >Chronic sleep loss is well studied, and it’s uniformly detrimental effects are widely documented,” Kozorovitskiy said. “But brief sleep loss — like the equivalent of a student pulling an all-nighter before an exam — is less understood.
I guess it also depends on what your past has been.
After going through a "sleep-deprived burnout cycle", I found that any all-nighter will pull me back into the emotions I got at that time, even if I feel originally great physically & mentally.
So, YMMV!
Re: One sleepless night can rapidly reverse depression for several days in mice
#38... in mice.
It is very well established in humans too. https://en.wikipedia.org/wiki/Wake_therapy
Indeed, the article title is a little misleading! Sleep depravation producing short-term improvements in human depression has been well known for some time. What the authors actually propose is an underlying mechanism to that improvement, in mice...
Re: One sleepless night can rapidly reverse depression for several days in mice
#39Weird, whenever I pull an all nighter my mood is usually noticeably depressed for the following two days.
I also used to be a bit of an insomniac, and one sleepless night could easily throw off my circadian rhythm, creating all sorts of extra anxiety, which translates into demand avoidance, stress and furthering depression.
Re: One sleepless night can rapidly reverse depression for several days in mice
#40i have noticed i have a sleepless night every once and a while, maybe once a month, and i usually have been feeling bad emotionally leading up to it. and i do usually feel better the next day, despite expecting to feel bad from no sleep
I always thought it was related to anxiety. After staying up late it feels like I'm forced to focus on what's important because I don't have the mental capacity to let my mind wander and worry about stuff.