One sleepless night can rapidly reverse depression for several days in mice
news.northwestern.edu
One sleepless night can rapidly reverse depression for several days in mice
1–10 of 312 posts
Re: One sleepless night can rapidly reverse depression for several days in mice
#2What's your secret? I'm always manic
Re: One sleepless night can rapidly reverse depression for several days in mice
#3Queue people blogging about their monthly “sleep fast” for optimized mood and focus.
Re: One sleepless night can rapidly reverse depression for several days in mice
#4This must be why new parents always seem so bubbly and happy!
But seriously, that’s very interesting and explains what I’ve experienced. I’ve been in a depression since quitting my phd a couple months ago and not having a direction in life, but whenever I have trouble sleeping I end up feeling better the next day. Maybe I’ll trying utilizing it to get my portfolio looking better.
Re: One sleepless night can rapidly reverse depression for several days in mice
#5... in mice.
Re: One sleepless night can rapidly reverse depression for several days in mice
#6This must be why new parents always seem so bubbly and happy! But seriously, that’s very interesting and explains what I’ve experienced. I’ve been in a depression since quitting my phd a couple months ago and not having a direction in life, but whenever I have trouble sleeping I end up feeling better the next day. Maybe I’ll trying utilizing it to get my portfolio looking better.
I went several years more or less depressed and observed this phenomenon and utilized it. Night of Kerbal Space Program and next day the world is much better. For a while. Also, a lot fuzzier. And I couldn't code very well (just good enough to do my job so everyone was happy but I could feel slipping).
Therapy and SSRI:s worked much better in the end.
But, for sure in a pinch it does alleviate unbearable darkness. The problem is it gives some, and takes a god damn lot - especially when entering middle age, when you (or I at least) can't shrug off sleep debt as easily.
The interesting thing is that this apparently was not well known during my therapy. I discussed this effect with my therapist, and she was skeptical and non-plussed. No hard feelings there, I'm super pleased she was robustly evidence based. But very happy to read these results in any case to validate my personal discovery.
Re: One sleepless night can rapidly reverse depression for several days in mice
#7i have noticed i have a sleepless night every once and a while, maybe once a month, and i usually have been feeling bad emotionally leading up to it. and i do usually feel better the next day, despite expecting to feel bad from no sleep
Re: One sleepless night can rapidly reverse depression for several days in mice
#8... in mice.
It is very well established in humans too. https://en.wikipedia.org/wiki/Wake_therapy
Re: One sleepless night can rapidly reverse depression for several days in mice
#9Once I go past 24hr I get really loopy and giggly.
Re: One sleepless night can rapidly reverse depression for several days in mice
#10This must be why new parents always seem so bubbly and happy! But seriously, that’s very interesting and explains what I’ve experienced. I’ve been in a depression since quitting my phd a couple months ago and not having a direction in life, but whenever I have trouble sleeping I end up feeling better the next day. Maybe I’ll trying utilizing it to get my portfolio looking better.
I noticed something similar (see also: my comment about using magnesium and getting better sleep on the thread about deep sleep yesterday).
When I get ~5ish hours of sleep one night a week I am surprisingly more alert the next day but I also crash much harder by night. I cannot sustain multiple days of little sleep but one short night doesn't seem to have such a detrimental effect.