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Study shows antibodies against PEG in 83% of the German population

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Re: Study shows antibodies against PEG in 83% of the German population

#111
post #109

Footnote: PEG = polyethylene glycol in this context. So the study is related with people developing allergy to cosmetics and industrial products.

It's also in candy and medicine (and antifreeze and ...)

RV anti-freeze, not the kind in your gas vehicle's radiator which is ethylene glycol.

Re: Study shows antibodies against PEG in 83% of the German population

#112
post #59
post #46

Earlier quoted context omitted.

i think it's almost certainly something about industrially-mass-produced food that tubs of butter don't share, so i think you're a bit closer to the mark. and sugary drinks are surely an especially bad food even among industrially-mass-produced foods clearly calorie density alone is not it. and i don't think it's even as simple as 'palatability'. even if you mix cacao, butter, sugar, vanillin, and citric acid into ca…

Modern fast food is deliberately engineered to make it as addictive as possible while still being palatable and cheap to produce, in order to maximize sales. That sounds more nefarious than I intended, so let me rephrase it. Modern fast food is the result of rapidly iterating, debugging, and optimizing recipes in a huge market for the last 70 years, leaving only the best selling, low cost, consistently reproducible r…

this is clearly a thing that has happened, and it is a crucial link in the chain, but there's still a missing link.

wouldn't it be more profitable if those recipes happened to have low caloric density, like coca-cola? then you could sell each customer six meals a day instead of three, and they'd be more profitable because they'd mostly be made out of water, which is cheaper than deodorized canola oil and palm oil, much less potatoes, texturized soy protein, mechanically separated chicken, and beef. you'd maybe have to include enough cellulose and xanthan gum to make it seem solid, but that wouldn't overcome the cost savings from removing the expensive calorie-bearing ingredients. it's even legal!

yet fast-food consumers have been gravitating to the macronutrient-rich menu items, not texturized carboxymethylcellulose jello, which would undoubtedly be widely available if it sold well. so they are following their homeostatic regulatory system to seek calories

their homeostasis is just broken

what broke the homeostasis?

i don't think it's an intentional thing or even a means to improve sales. if wendy's breaks your homeostatic feedback and mcdonald's doesn't, will that help them competitively? no, because their metabolically damaged customers will still eat at mcdonald's, except for the most loyal ones. if wendy's goes out of business, it'll take a generation for mcdonald's to see the result in terms of declining sales. even then, they're unlikely to be able to recognize that the demise of wendy's is the reason for their troubles

it's plausible that it's nothing more than 'ultra-palatable food makes you overeat, which disrupts your homeostasis'. but i'm skeptical of that because people seem to be able to eat very palatable food occasionally, or even often, without disrupting it

Re: Study shows antibodies against PEG in 83% of the German population

#113
post #30

Earlier quoted context omitted.

olive oil has been widely available for the last 7000 years, butter for ten thousand years, but the obesity pandemic is only 50 years old

Let's be real though - sugar tends to be a lot more palatable than butter, especially when baked or dissolved in acid. I could eat an entire bag of crunch bars, but set me down with a box of sticks of butter and I'm not going to make much progress. Fats also tend to be more filling, and aren't as addictive as sugar, especially refined sugar. So I think the real cause here is we've discovered novel ways for making hug…

Fruits are not calorically dense. A huge ripe pear can be incredibly delicious and sweet, and only has like 100 calories. The best peach you've ever eaten is like 60-80. It would be pretty challenging to eat a calorically problematic portion of them.

A better example is probably nuts. Nuts are super calorically dense, and it's easy to loads of them.

Re: Study shows antibodies against PEG in 83% of the German population

#114
post #30

Earlier quoted context omitted.

I think the primary cause of the obesity epidemic is the widespread availability of cheap calorie dense food and a few hundred million years of evolution devoted to making biological machines designed to consume as much calorie dense food as they could find.

olive oil has been widely available for the last 7000 years, butter for ten thousand years, but the obesity pandemic is only 50 years old

People are reaching for expense, but I think that's the wrong explanation, it's cost/availability + palatability + caloric density. Olive oil has maybe one or two of those, but it's missing the key ingredient of palatability. Not many people want to guzzle olive oil.

Re: Study shows antibodies against PEG in 83% of the German population

#115
post #19

i guess they'll just have to use lalr(1) more seriously, i wonder if something like this is a cause of the obesity pandemic: an unrecognized widespread immune response to a novel food additive provoking continuous low-level inflammation though probably not peg itself; e1521 is not in that many foods, not like xanthan gum or nanoparticles of titanium dioxide

> i guess they'll just have to use lalr(1)

I see what you did there. :-) I myself was momentarily confused when I saw "PEG".

Re: Study shows antibodies against PEG in 83% of the German population

#116
post #114
post #30

Earlier quoted context omitted.

olive oil has been widely available for the last 7000 years, butter for ten thousand years, but the obesity pandemic is only 50 years old

People are reaching for expense, but I think that's the wrong explanation, it's cost/availability + palatability + caloric density. Olive oil has maybe one or two of those, but it's missing the key ingredient of palatability. Not many people want to guzzle olive oil.

> Not many people want to guzzle olive oil.

I myself find good olive oil to be quite tasty, far more so than soybean or canola, and I don't think I'm in a tiny minority there. Dipping bread directly in olive oil (sometimes seasoned with a little garlic or whatever) is very common in Mediterranean diets.

Re: Study shows antibodies against PEG in 83% of the German population

#117
post #39

Earlier quoted context omitted.

Both of those until very recently were extremely expensive to the point of luxury for many, as well as much more difficult to effectively use a lot of cheap and easily. Effectively zero people are chugging bottles of Olive Oil they buy from the corner store. There just is no comparison whatsoever to modern processed foods set for immediate consumption and tuned for maximum taste and pleasure response. Edit: to refute…

> Culture has simply changed, and (bad) food has gotten to be incredibly cheap and easy to access. It’s Gresham’s “law”: “bad money drives out good”, but applied to food. https://en.m.wikipedia.org/wiki/Gresham's_law

people hoard good food in their vaults while giving other people their bad food as quickly as they can, because the government has decreed that bad food is equivalent to good food?

that's total nonsense. gresham's law doesn't apply to food

Re: Study shows antibodies against PEG in 83% of the German population

#118
post #113

Earlier quoted context omitted.

Let's be real though - sugar tends to be a lot more palatable than butter, especially when baked or dissolved in acid. I could eat an entire bag of crunch bars, but set me down with a box of sticks of butter and I'm not going to make much progress. Fats also tend to be more filling, and aren't as addictive as sugar, especially refined sugar. So I think the real cause here is we've discovered novel ways for making hug…

Fruits are not calorically dense. A huge ripe pear can be incredibly delicious and sweet, and only has like 100 calories. The best peach you've ever eaten is like 60-80. It would be pretty challenging to eat a calorically problematic portion of them. A better example is probably nuts. Nuts are super calorically dense, and it's easy to loads of them.

not if you have to shell them yourself

Re: Study shows antibodies against PEG in 83% of the German population

#119

Earlier quoted context omitted.

I get a colonoscopy every n years. Where n is some number between 1 and 5, depending on whether they found polyps or something the previous time. It's not that onerous, except that I assume going under propofol + midazolam comes with cognitive risks each time, and this might be cumulative. With that in mind, no idea how the risk/reward math of regular endoscopy/colonoscopy checkups works out.

Having seen now 3 people die of colon cancer in their early 30s, I can see why early and frequent detection makes sense.

Damn... see any patterns, in lifestyle, diet etc?

Re: Study shows antibodies against PEG in 83% of the German population

#120
post #30

Earlier quoted context omitted.

I think the primary cause of the obesity epidemic is the widespread availability of cheap calorie dense food and a few hundred million years of evolution devoted to making biological machines designed to consume as much calorie dense food as they could find.

olive oil has been widely available for the last 7000 years, butter for ten thousand years, but the obesity pandemic is only 50 years old

This is extremely disingenuous. You cannot drink anything more than a little bit of olive oil without serious gastric consequences, which is why most of history involves using a little bit of vegetable oil here and there for the other desirable properties. Nevermind the fact that nobody could afford large quantities of ANY food, and even after we brought the potato, a way more efficient means of growing calories, to europe, most people still couldn't afford more than sufficient quantities of calories. Even then, there are arguments to be made that such potato growing was an important element of significant population growth after it became popular.

Meanwhile, you average normal person nowadays CAN eat a bag of potato chips in one sitting, without gastric consequences. Then they can compensate for eating half a pound of salt by following it up with half a candy bar for something sweet. Or maybe they got a milkshake with their burger or something.

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