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My Left Kidney

astralcodexten.com

61–70 of 325 posts

Re: My Left Kidney

#61

Earlier quoted context omitted.

No, you can blame EAs for making stupid decisions and being generally bad people if they are making stupid decisions and being generally bad people. I'll second that I'm sorry for the bad experiences you've had with EAs. In my experiences, lots of them are simply good people trying to do more good. I hope you can have better experiences with them in the future.

I won't have better experiences with them in the future because the moment I discover someone is an EA I no longer have experiences with them, period.

This is deeply fallacious binary thinking.

Take anything you like. A cause, religious group, political party, sports fanbase, etc.

Some subset of each group are generally decent people, who do their best to be good to the people around them, and to live their lives in a generally moral and ethical manner.

Some subset of each group have no interest in morals or ethics, and attach themselves to the group for purely selfish reasons.

Judging the entire group based on the selfish or amoral subset is a logical fallacy of the most basic sort, and is bordering religiosity. This is even more problematic when you look at the kinds of negative EA situations that have (rightly) caused controversy. The high profile big money cases get attention.

If confronted with someone who ascribes to the EA philosophy and by all measurable indicators has done incredibly good things for the world, would you be willing to change your mind?

Re: My Left Kidney

#62

This does honestly kind of shock me, it’s respectable that he did something like this for a random person but I could never imagine myself doing it for anyone except close family. I used to think EA was some kooky AI safety Cult but if so many EA folks donate their kidney, my opinion of them has improved far more. They at least have balls!

> I used to think EA was some kooky AI safety Cult but if so many EA folks donate their kidney, my opinion of them has improved far more. They at least have balls!

They are both a kooky AI safety Cult and they do things like donate kidneys and fund malaria nets.

They are a kooky AI safety cult because there is a reasonable argument to make that AGI is the most plausible, preventable human extinction event[1] in the near future. If you believe that argument, then starting (or joining) a kooky AI safety cult seems like a really good idea.

1: It's not clear that an asteroid large enough to wipe out all humans could be prevented with technology we can develop in the next 100 years or so. Global warming is bad and all, but it might kill a couple billion people, not wipe us all out. Total global nuclear war probably won't even kill 100% of the population of all of the countries involved, and large parts of Africa are unlikely to get bombed at all.

Re: My Left Kidney

#63

It's human nature to feel good about themselves by doing certain "altruistic" things. Make no mistake the donor benefits more than the recipient.

> So in total, a donation produces about 10-20 extra quality-adjusted life years. How much would you say the donor benefits?

It depends on the QoL improvement factor you assign to self-satisfaction I suppose? Just multiply that by the expected number of years left in their life.

Re: My Left Kidney

#64
I know a few people who have donated kidneys (both to friends and strangers), and I find it admirable (and supererogatory).

At the same time, I think this post demonstrates a kind of selective unawareness that I’ve seen members of the EA community demonstrate. A significantly less charitable summary of Scott’s situation is “our prospective kidney donor is newly-married high-stress professional with a history of SSRI usage who has recently experienced significant negative public attention and belongs to an actively-imploding community/cult.” This is almost certainly what the UCSF administrators perceived, and his latent hostility to them almost certainly didn’t help.

This doesn’t necessarily justify their decision (maybe they are just bureaucrats), but it’s a framing that’s roughly as plausible as the bucolic EA one that’s presented. A community that has a self-stated mission in rationality should be able to see that.

Re: My Left Kidney

#65

This does honestly kind of shock me, it’s respectable that he did something like this for a random person but I could never imagine myself doing it for anyone except close family. I used to think EA was some kooky AI safety Cult but if so many EA folks donate their kidney, my opinion of them has improved far more. They at least have balls!

A lot of EAs, including the author of this piece, are also really into IQ, eugenics and "human biodiversity" (aka race science). Consider that Scott Alexander (aka squid314) once expressed a desire to donate to "Project Prevention", a eugenics charity formulated to pay undesirables to sterilize themselves [1][2].

[1] https://en.wikipedia.org/wiki/Project_Prevention [2] https://web.archive.org/web/20131230050925/http://squid314.l...

Re: My Left Kidney

#66

Hopefully the Ozempic breakthroughs will alleviate some of the need for kidney donation as it lowers the occurrences of End-Stage Renal Disease (ESRD).

There was recent news on an Ozempic study that shows reduced risk kidney conditions for diabetic patients.

> Based on the trial’s design, Ozempic needed to reduce the absolute risk of one of those kidney-related conditions by at least 3.5% when compared to placebo, or a relative risk reduction of around 16.5%, Akash Tewari, a Jefferies analyst who covers Lilly, wrote in a note to clients.

https://www.biopharmadive.com/news/novo-nordisk-ozempic-kidn...

Re: My Left Kidney

#67
While I've appreciated some of the author's articles in the past, I think the numbers in this one miss the mark quite a bit.

> the risk of dying from the screening exam was 1/660

> The usual rule of thumb is that one extra Sievert = 5% higher risk of dying from cancer, so a 30 mS dose increases death risk about one part in 660.

Well not quite. First of all, this assumes that exposure events are additive over a lifetime (rather than individual events being more damaging at higher doses). This does seem to be the case, though I'm curious if we really know.

More to the point, it's a 5% increase of chance of death from cancer. Combining 5% with 30mSv/1Sv, you get an extra 0.15% chance of dying of cancer indeed.

But the chance of dying of cancer in the U.S. is something like 17.5%, although that does increase (and then decrease) with advanced age. According to https://usafacts.org/articles/americans-causes-of-death-by-a... , something like 29% deaths in the 65-74 age group are cancer, while in the 75-84 year age group it drops again to 25%.

Regardless, this means if you figure out your lifetime chance of dying by cancer based on your current age, it's 30% at the most (in aggregate, obviously personal risk factors vary a lot from person to person).

A 0.15% increase in that is 0.045% additional chance of dying by cancer, or 1 in 2,222. Using the average mortality incidence of 17.5% its more like 1 in 3800. And for someone who's this concerned about dying of cancer and I assume limiting risk factors much more than the average citizen, perhaps it's a 1 in 5000 chance.

All in all you're much more likely to reduce your chance of death by cancer by much more than a CT will increase it, via a number of lifestyle changes: healthier eating, quitting alcohol, staying out of the sun.

Re: My Left Kidney

#70
This was actually really helpful to me as a person with CKD. Some of the possible risks & issues I’ve had clicked after reading it. I hadn’t considered that, even if I’m not actively dying of CKD, I could be experiencing degraded function in other ways. Useful to know.
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