Live data from Hacker News

CVS ditches common cold meds after FDA advisers say they're useless

arstechnica.com

151–160 of 275 posts

Re: CVS ditches common cold meds after FDA advisers say they're useless

#151
post #65

Wasn't this the one they substituted with a half arsed version because the real deal was being bulk bought and cooked into meth? I guess new version being useless for meth cooking isn't the only thing it is useless at

and it's done nothing to curtail the availability of methamphetamine.

But, sure, it's put a lot of grandma's in jail

https://reason.com/2009/09/30/put-down-the-cold-pills-grandm...

Re: CVS ditches common cold meds after FDA advisers say they're useless

#152
post #18

Earlier quoted context omitted.

It's already easy to buy the stuff that works. You just have to go up to the counter and ask. You have to show ID, just like you do for liquor (and, because purchases of psuedoephedrine are rate-limited, they're going to log your purchase). You'll need to get over that, because I don't think the rate limit is going anywhere: psuedoephedrine essentially is methamphetamine, and it's the worst conceivable kind: the kind…

> You just have to go up to the counter and ask. You have to show ID, just like you do for liquor (and, because purchases of psuedoephedrine are rate-limited, they're going to log your purchase) Up to the counter and ask...when the counter is open that is increasingly a problem as pharmacies close and hours are limited (the two nearest me close at 6pm, right at the end of working hours). Show ID...that the pharmacist…

> Show ID... [...] (not all of us drive or have a driver license).

Your objection is irrelevant. States give photo IDs which are just like drivers licenses except they don't say "drivers license", you don't have to pass any driving tests, and you can't drive with them. Otherwise they look and work the same and every employee trained to look at drivers licenses will accept them without hesitation.

Re: CVS ditches common cold meds after FDA advisers say they're useless

#153

Earlier quoted context omitted.

> What health and wellness items can I order for same-day delivery? We've got you covered on health and wellness items including over-the-counter medicine, vitamins, first aid items, family planning items, feminine care products, home diagnostic tests, and more to help you feel better in a pinch. https://www.doordash.com/p/medicine-delivery Just checked and you totally can buy psuedo via door dash ¯\_(ツ)_/¯ https://i…

Interesting, when I search on DoorDash everything that comes up is phenylephrine. No pseudoephedrine to be found. What state do you live in?

Not today, officer ╭∩╮(︶_︶)╭∩╮

/s

Re: CVS ditches common cold meds after FDA advisers say they're useless

#154

Earlier quoted context omitted.

You might be thinking of aspirin, which is toxic at fairly low dosages. Acetaminophen (aka Tylenol) is much, much safer.

Acetaminophen has a narrow therapeutic index and can cause severe and irreversible liver injury in doses around 10 g. A single tablet usually contains 500 mg, but because it's a component of so many other "combo" cold meds, including some syrups, it's easy for people to overdose while mixing OTC products to get over a flu. Aspirin has a lower standard dose (325 mg), higher LD50 (probably around 20-25 g), and is gener…

> Ibuprofen is probably the safest option?

Are you kidding? Ibuprofen like most NSAIDS is terrible on the GI tract and the kidneys. People with healthy kidneys are usually fine with short courses, but even people with relatively mild chronic kidney disease should avoid NSAIDs.

People in their 20s that overuse NSAIDs end up needing kidney transplants. it's not that uncommon. The most common cause of peptic ulcer disease of this demographic (affluent westerners) after H pylori is NSAID use.

> It has fallen out of favor because it's known to cause an exceedingly rare but deadly syndrome in a tiny percentage of children

This has really nothing to do why aspirin has less common use among adults. Aspirin has poor analgesic effects relative to the doses and the risks of GI complications.

> acetaminophen results in tons of hospitalizations every year.

The impact of NSAID related complications is far greater in terms of kidney transplants and upper endoscopy interventions, and related ICU stays.

Re: CVS ditches common cold meds after FDA advisers say they're useless

#155

My understanding is that they are only removing products that ONLY contain Phenylephrine, which means they will still sell it when it is part of multiple-ingredient formulations, which are in themselves kind of a scam. For example, many OTC "severe cold/flu" formulations contain: - Acetaminophen. Potentially helpful for the body aches that come with the flu, but a lot of the time when I'm sick, I don't exactly need o…

>If you have a fever it can reduce it, but for a minor fever I'm not sure that is necessary.

I think it's generally good to have a mild fever since it's how your body makes itself inhospitable to viruses

Re: CVS ditches common cold meds after FDA advisers say they're useless

#156

psuedoephedrine is the only one that works.

And it works really well.

I have some debilitating allergies during the summers and it's basically benadryl or pseudoephedrine. If I want to stay remotely functional, I need pseudoephedrine.

Re: CVS ditches common cold meds after FDA advisers say they're useless

#157
post #146

Earlier quoted context omitted.

Well if you have a passport, which is federal ID, of course you don't need a state ID. But there are plenty of people who have criminal records that would prevent them from getting a passport, as well as plenty of people who just don't want the couple week process and complexity of getting a passport, or don't want to carry a bulky book when all they need is 1 page from it, and who have no intention of leaving the co…

> or don't want to carry a bulky book when all they need is 1 page from it, and who have no intention of leaving the country US passports are available in card form for exactly these people. They work the same as a book-style passport within the US, but can't be consistently used for international travel. https://travel.state.gov/content/travel/en/passports/need-pa...

TIL, thanks!

Re: CVS ditches common cold meds after FDA advisers say they're useless

#158

Earlier quoted context omitted.

You might be thinking of aspirin, which is toxic at fairly low dosages. Acetaminophen (aka Tylenol) is much, much safer.

Acetaminophen has a narrow therapeutic index and can cause severe and irreversible liver injury in doses around 10 g. A single tablet usually contains 500 mg, but because it's a component of so many other "combo" cold meds, including some syrups, it's easy for people to overdose while mixing OTC products to get over a flu. Aspirin has a lower standard dose (325 mg), higher LD50 (probably around 20-25 g), and is gener…

> Ibuprofen is probably the safest option?

I've heard it can damage the stomach lining if taken at the wrong time relative to eating. But yeah probably still the least-bad first-resort painkiller.

Re: CVS ditches common cold meds after FDA advisers say they're useless

#159
post #18

Earlier quoted context omitted.

It's already easy to buy the stuff that works. You just have to go up to the counter and ask. You have to show ID, just like you do for liquor (and, because purchases of psuedoephedrine are rate-limited, they're going to log your purchase). You'll need to get over that, because I don't think the rate limit is going anywhere: psuedoephedrine essentially is methamphetamine, and it's the worst conceivable kind: the kind…

It's not easy in my state. It goes like this: go to inside counter of an open pharmacy (can't use drive thru for it). Wait, for a long time (aren't all of your pharmacies massively overloaded with 30-60m lines? ours are). Ask for a 96-count sudafed (generic or regular) and hope they have it. If they don't, get 48. If they don't, get 24 (forget that I need 2 tabs every day as prescribed by my doctor -- yet can only bu…

> Sudafed is one of the hardest to acquire substances out there

What!?? Regardless, this tip might be helpful: you can get it online with a script without insurance for $2.40 [1]

If you need a script you can probably get it from Amazon Clinic Dr chat too for $33 without insurance all via messages only. [2]

For the record I've never used it and haven't considered it much beyond my recent amazement how theres a 'startup' for every prescription med now (and Amazon is entering the market strong too).

[1] https://pharmacy.amazon.com/Pseudoephedrine-Oral-Tablet/dp/B...?

[2] https://clinic.amazon.com/cough-cold-flu-treatment/dp/B0CK3K...

Re: CVS ditches common cold meds after FDA advisers say they're useless

#160

My understanding is that they are only removing products that ONLY contain Phenylephrine, which means they will still sell it when it is part of multiple-ingredient formulations, which are in themselves kind of a scam. For example, many OTC "severe cold/flu" formulations contain: - Acetaminophen. Potentially helpful for the body aches that come with the flu, but a lot of the time when I'm sick, I don't exactly need o…

The market is essentially just one step beyond basic snake oil. Instead companies mix various "approved" ingredients to create some branded concoction that they hope will stick from psychosomatic effects. For example "Excedrin" is just aspirin+acetaminophen+caffeine yet so many people swear by it rather than popping the two simple pills and considering if they really need another cup of coffee. The worst is when brand names are abused with suffixes to mean wildly different drugs, as if affinity for a corporate brand should come before consideration of the active ingredients.

Similar deceit happens with cleaning products, where "Clorox" spray or "Clorox" wipes aren't bleach at all. Rather the spray is just some mild acid (a poorer disinfectant), and the wipes are quat (aka "Lysol", makes your pets sick). This kind of thing should be patently illegal - any brand should be required to have consistent active ingredients.

Of course this isn't even considering the criminalization of well-working pseudoephedrine due to the government's dark ages persecution of drug-users-plus-everyone-else.

Post reply on HN