Live data from Hacker News

Psychedelic Mushrooms Hit the Market in Oregon

nytimes.com

271–280 of 317 posts

Re: Psychedelic Mushrooms Hit the Market in Oregon

#271

Earlier quoted context omitted.

For what it’s worth you can find psilocybin in the US with with right network that does not require exorbitant costs or travel.

Heck, It’s grows in many part of the country!

More like most parts of the country! There's at least one species of psilocybin mushroom for most states. The Shroomery is a great starting resource.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#272

Earlier quoted context omitted.

Prozac is my fun drug. It makes me hypo manic with one 20mg dose. I have schizoaffective disorder, bipolar type So I am prone to being more sensitive to SSRI. This is mostly to do with my genetically odd 5HT2A receptors. Depression is no longer really a part of my life anymore after I found I was zinc deficient. But now I do tend towards the manic and have issues with psychosis still so I need to be careful with my s…

How do you get the right amount of zinc? Are there other minerals you're supposed to take with zinc? I know that sometimes balancing one thing causes another thing to go out of balance.

My doctor is great and test both my zinc and copper regularly. So I only take zinc when my levels are getting close to the low level.

Zinc can inhibit the observe shows copper, so that’s why the copper tested.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#273

Earlier quoted context omitted.

I believe that we are pretty sure that serotonin has nothing to do with how SSRIs alleviate depression, despite the name.

I believe the only thing we are pretty sure about is that we don't know why SSRIs work. What we believe we know is that low serotonin in the brain does not directly cause depression, and artificially lowering serotonin in individuals does not induce depression (at least not in the way researchers have done so, within the time limits they measured). None of this necessarily means that SSRI activity downregulating the…

You know why SSRIs work for some people and don’t work for others, because the people who it doesn’t work for don’t have depression caused by serotonin deficiency. Their depression is most likely caused by too much GABA.

Depression is a multi causal disorder.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#274
I find it odd that most states legalize pot before they legalize/decriminalize shrooms. Psilocybin mushrooms are native to a lot more states than cannabis. It's an odd experience to walk down the streets of NJ and see a patch of Psilocybe Ovoideocystidiata growing in a mulch bed and to think, "Wow! A natural fungal felony with freewill and a means to reproduce, turning other people's mulch beds into felonies!"

Re: Psychedelic Mushrooms Hit the Market in Oregon

#275

Earlier quoted context omitted.

That God kinda-became human to "sacrifice" himself (with no loss, got up 3 days later to live forever, nothing was sacrificed) in order to forgive the sins of people, but only if they believe it, isn't spiritual, it's silly. You owe someone something, and someone else or that person pays it for you -- but if you don't believe that happened, it never happened. Great stuff. I don't need to have an answer for life, the…

Consider you are developing a genetic algorithm with the goal of creating a cohort of entities that have the ability to pursue light. Each generation, you initialize a set of start states based on the prior generation and let things play out according to your rules. In the end, you persist those that found the light by taking their information and carrying it on in some sense in the next generation. The information o…

[deleted]

Re: Psychedelic Mushrooms Hit the Market in Oregon

#276
post #13

Earlier quoted context omitted.

> We know that the microdosing also turned into macrodosing on a lot of occasions. It's pretty easy to slip into this. I don't have a good answer for solving this but criminalization is definitely a bad answer, so we will have to find a way to discourage such tendencies. It may be that it is mostly or entirely a cultural thing in which case public understanding of the drug is a prerequisite, so I'm glad more are star…

This thread found me at the perfect time I swear. A friend of mine just gave me a huge amount of shrooms. I've always been excited about microdosing, so I tried my first .4 grams the other day and felt a great layer of good vibes that day. I was going to increase the dose, knowing it's not really microdosing and figuring I could do this on a regular basis. I'm now taking this thread as a sign to slow my roll.

over a year ago, on this platform, you were praising how amazing elon was. do you still think so?

Re: Psychedelic Mushrooms Hit the Market in Oregon

#277
post #240
post #237

Earlier quoted context omitted.

> Those are MENTAL withdrawal symptoms, not PHYSICAL ones. That is an interesting line to draw. Are "MENTAL withdrawal symptoms" not neurological in nature? Are "hallucinations or the shakes or seizures" not based in neurology?

The DTs from alcohol withdrawal can outright kill you. That’s the line I draw. Similar for other meds that have very unpleasant effects if you don’t taper off over weeks or even months.

Still neurological in nature.

Delirium tremens is a severe form of alcohol withdrawal. It involves sudden and severe mental or nervous system changes.

Delirium tremens may also be caused by head injury, infection, or illness in people with a history of heavy alcohol use.

https://medlineplus.gov/ency/article/000766.htm

Re: Psychedelic Mushrooms Hit the Market in Oregon

#278

Earlier quoted context omitted.

> We know that the microdosing also turned into macrodosing on a lot of occasions Do you know how frequent the macrodosing became? I have never seen or heard (anecdotal) of microdosing leading to a psychotic break. But frequent use (more than once every three weeks) of large quantities will almost certainly harm you in the long run.

The last time we hung out before all this went down, we had a few drinks then she broke out the acid, saying we would just microdose and it would be mostly like a really strong cup of coffee. Of course we ended up doing another microdose, which I'd estimate ended up at about 1/4 of a serious acid trip. I assume stuff like that happens a lot in her Phish group. Other times we've hung out at a party she's broken acid/e…

Thank you for sharing your experiences; I'm sure it's hard to see your friend go down that road.

From my experience, the psychedelics will "tell you" to slow down, but it's up to the individual to make that choice.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#279
post #46

Earlier quoted context omitted.

[flagged]

I’m pretty agnostic, but what are you answers to seemingly untraceable questions of life, meaning, and existence? I’m starting to come around to the view that ridicule of religiosity is quite often more vacuous than spirituality.

Yeah, I'm 100% atheist, but often feel horrified by the shallow understanding of religion and theology that many other atheists exhibit. I want shake them and say "do you really think you're smarter than Thomas Aquinas?"

Sure, he was wrong... but not worthy of ridicule. It's just so easy and satisfying to assume that disagreement indicates stupidity.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#280
post #257

Earlier quoted context omitted.

Ayahuasca is a classical psychedelic and the interaction risk with SSRIs is extremely high.

Ayahuasca contains monoamine oxidase inhibitors compounds too, those are the cause of the interaction. Dimethyltryptamine itself does not carry the same interaction risk. It's a mix of monoamine oxidase inhibitors and dimethyltryptamine to prevent the stomach acid decomposing active drug.

I’m just clarifying because you said it was low risk and there’s at least one case of it being high risk.
Post reply on HN