Live data from Hacker News

Psychedelic Mushrooms Hit the Market in Oregon

nytimes.com

151–160 of 317 posts

Re: Psychedelic Mushrooms Hit the Market in Oregon

#151

I'm a fairly drug-averse person. I have no qualms about other people using them, but it took us over 30 years to really understand the implications of legalized opioids. And that was after a lengthy and expensive FDA process. So respect to all of the early adopters who have nothing to lose and are willing to put their own sanity at risk. I just don't understand people who in one breath curse the Sackler family but th…

>but it took us over 30 years to really understand the implications of legalized opioids.

It took the EU all of ten seconds to reject opiates for minor use -- the opioid crisis is very much manufactured and endured in North America and is a regulatory failing of the FDA. The most crucial distinction here is the addictiveness of psilocybin vs opioids, mushrooms are not remotely addictive relative to opioids.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#152
post #19

Earlier quoted context omitted.

Counterpoint: SSRIs were transformative for my depression. Side effects were minor and manageable (eg, Wellbutrin worked well to prevent any sexual dysfunction). I was on them for several years and had no problem tapering off. My understanding is that this is a pretty typical experience. Rhetoric like this was actively harmful in dissuading me for years from trying what ended up being by far the most effective treatm…

Wellbutrin is not an SSRI, but a NDRI (norepinephrine and dopamine reuptake inhibitor). Some people respond better to the latter.

I take Wellbutrin and I’m not sure what it does for other people, but for me, it gives me a buffer of patience to draw from that I didn’t really have before. Negative or frustrating events don’t feel quite as urgent and I’m able to calmly move forward better than I can without it. Which is very helpful when you’re taking care of kids.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#153
post #3

What's missing from this article is that people are reaching for this because the standard medical treatment for these disorders, SSRIs, are pretty terrible. In the mild case, the common side effects are blunting of your emotions and sexual dysfunction. So you don't have panic attacks, but you live in a gray fog and your relationships suffer. In the worst case, they cause suicidal ideation. Psychedelics also have psy…

> In the mild case, the common side effects are blunting of your emotions

Isn't this the primary effect, more than a side effect? Atleast in my case, it's been super helpful, going from jumping between a 1 to 7 in mood, to just lie around 4-5-6.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#154

Earlier quoted context omitted.

I’m pretty agnostic, but what are you answers to seemingly untraceable questions of life, meaning, and existence? I’m starting to come around to the view that ridicule of religiosity is quite often more vacuous than spirituality.

That God kinda-became human to "sacrifice" himself (with no loss, got up 3 days later to live forever, nothing was sacrificed) in order to forgive the sins of people, but only if they believe it, isn't spiritual, it's silly. You owe someone something, and someone else or that person pays it for you -- but if you don't believe that happened, it never happened. Great stuff. I don't need to have an answer for life, the…

Yes, some of those things do sound silly... but they are not at all what most Christians believe.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#155

Earlier quoted context omitted.

Same here. Did it once and it saved my life. Point is it was only legally accessible to rich people. I.e. I had to fly to amsterdam pay for pre and post psychotherapy and multi day care. This is so wildly different to recreational use.

For what it’s worth you can find psilocybin in the US with with right network that does not require exorbitant costs or travel.

Any potential for incarceration or institutionalization is an exorbitant cost to factor into transacting with the "wrong" network.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#157
post #19

Earlier quoted context omitted.

Counterpoint: SSRIs were transformative for my depression. Side effects were minor and manageable (eg, Wellbutrin worked well to prevent any sexual dysfunction). I was on them for several years and had no problem tapering off. My understanding is that this is a pretty typical experience. Rhetoric like this was actively harmful in dissuading me for years from trying what ended up being by far the most effective treatm…

Same. I'm a big time psychedelic advocate, and relatively frequent consumer. Prozac actually saved my life. Psychedelics since have certainly enhanced it, but they could not accomplish what prozac did. I can go into more detail if interested.

Same here, but sertraline.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#158

Earlier quoted context omitted.

Wellbutrin is not an SSRI, but a NDRI (norepinephrine and dopamine reuptake inhibitor). Some people respond better to the latter.

I take Wellbutrin and I’m not sure what it does for other people, but for me, it gives me a buffer of patience to draw from that I didn’t really have before. Negative or frustrating events don’t feel quite as urgent and I’m able to calmly move forward better than I can without it. Which is very helpful when you’re taking care of kids.

This has been my experience with citalopram as well. The negative side effect though is that natural highs are lower, so I view it very much as a mood stabilizer.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#159
post #85
post #7

I'm not a medical person. Is there a readable summary of the research on therapeutic uses of magic mushrooms for laypeople?

There’s a bunch of fake studies that won’t replicate in 20 years when we’ll try to understand why we started frying peoples brain

Since millions of people have been taking mushrooms for thousands of years without this side effect, it seems unlikely we'll suddenly start finding fried brains.

Re: Psychedelic Mushrooms Hit the Market in Oregon

#160

Earlier quoted context omitted.

That God kinda-became human to "sacrifice" himself (with no loss, got up 3 days later to live forever, nothing was sacrificed) in order to forgive the sins of people, but only if they believe it, isn't spiritual, it's silly. You owe someone something, and someone else or that person pays it for you -- but if you don't believe that happened, it never happened. Great stuff. I don't need to have an answer for life, the…

Yes, some of those things do sound silly... but they are not at all what most Christians believe.

[flagged]
Post reply on HN