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Low serotonin levels might explain some Long Covid symptoms, study proposes

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Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#121

Post by swah »

btheunissen wrote: post #112
thenerdhead wrote: post #32

For people who are obviously ignorant of long covid in this thread, go read these publications and watch these videos: https://www.thelancet.com/journals/laninf/article/PIIS1473-3... https://www.nature.com/articles/s41590-023-01601-2 https://www.nature.com/articles/s41586-023-06651-y https://www.youtube.com/watch?v=z189Z7tS1w4 https://www.youtube.com/watch?v=VYNMzaZk_iU The researchers here have a specific hypothesis…

I’d been suffering from some “depression lite” symptoms, mostly generalized anxiety since 2020, maybe long covid, who knows, and a reasonably small prescription of Xoloft has had a huge change in my mood/life.

That's interesting - did the psychiatrist explained it like that ? I feel the same way for so many months, but also wouldn't call depressed. Just always anxious, never rested, always in a mood... I attribute to work and other stresses though.

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#122

Post by gmd63 »

mcpackieh wrote: post #97
gmd63 wrote: post #77

Earlier quoted context omitted.

* short-term economic growth

Having most of the population holed up inside is bad for long-term economic growth too. Ineffectual internet-schooling replacing normal in-person schooling for more than a short time period would be particularly devastating to long-term economic growth.

That's conjecture and based on intermediate metrics such as report cards / SAT scores

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#123

Post by ck2 »

Common in this thread and every thread about long-covid is the lack of understanding that there is more than one kind of long-covid.

For the deniers here is the work of Brandon Gilles who was a hacker like us, who died from long-covid

he tried everything, methodically, with great research, to no avail

https://docs.google.com/document/d/1X3dNPgEuQ2j8x7w8OqLEDP7l...

https://twitter.com/BrandonGilles

https://discuss.luxonis.com/blog/2078-in-loving-memory-celeb...

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#124

Post by Manuel_D »

ChrisRR wrote: post #87
PrayagBhakar wrote: post #71

Earlier quoted context omitted.

I’m confused why folks think long covid isn’t real? Most disease have long lasting effects. Why not covid?

Just ignore them. These nutjobs are made not believing in covid the entire personality so that they could feel smart, and now they have to cling to that belief instead of accepting reality

There's a vast difference between denying the very existence of COVID-19 and skepticism of long-COVID. Nobody doubts the existence of Lyme disease. The existence of Chronic Lyme disease is generally rejected.

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#125

Post by interactivecode »

btheunissen wrote: post #112
thenerdhead wrote: post #32

For people who are obviously ignorant of long covid in this thread, go read these publications and watch these videos: https://www.thelancet.com/journals/laninf/article/PIIS1473-3... https://www.nature.com/articles/s41590-023-01601-2 https://www.nature.com/articles/s41586-023-06651-y https://www.youtube.com/watch?v=z189Z7tS1w4 https://www.youtube.com/watch?v=VYNMzaZk_iU The researchers here have a specific hypothesis…

I’d been suffering from some “depression lite” symptoms, mostly generalized anxiety since 2020, maybe long covid, who knows, and a reasonably small prescription of Xoloft has had a huge change in my mood/life.

Im curious to learn more. Was that with a one time prescription of xoloft or are you taking it regularly?

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#126

Post by local_crmdgeon »

mcpackieh wrote: post #80
local_crmdgeon wrote: post #63

Earlier quoted context omitted.

We over diagnose. It's taboo to discuss the fact that population is tumblr/twitter types, and not people that are well adjusted. It's a contagion, but it's not spread by a virus. Most people with Long COVID recover through increased exercise and improved diet. They're just depressed, which is of course a real illness, but it's more to do with burn out from social media hysteria. Any mention of this on HN results in i…

"It can't be depression because my wife has it. You need to do more research, please subscribe to doomerist facebook groups to read all about it."

We've both been downvoted to oblivion, which at this point means we're right. COVID really broke a lot of people mentally

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#127

Post by Podgajski »

ChrisRR wrote: post #95
Podgajski wrote: post #34

Earlier quoted context omitted.

You shouldn’t be surprised at this at all. There is zero profit motive for the amount of money it would take to do a vitamin D trial since no one can patent vitamin D.

I always feel like the people who make these sort of comments have never actually read a medical journal. A huge amount of study does not lead to patentable medication, but is either performed by research groups, or is performed as part of R&D of another products and then published in papers.

I have been reading medical journals for 12 years and I have collaborated on a study that is looking into manganese transport and/or deficiency as a possible cause of ME/CFS and Long Covid.

There is a difference between something that could never be patented (Vitamins), and the possibility of something working becoming patented (Prozac for example).

The first does not get the funding but from benefactors, as in the case of the study I collaborated with.

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#128

Post by thenerdhead »

PathOfEclipse wrote: post #113
VikingCoder wrote: post #100

I still think about the HN commentor who told me confidently, "there is no theoretical basis for long-term consequences of COVID-19." [1] [1] https://news.ycombinator.com/item?id=23875391

Thanks for pointing me to that comment so I could upvote it. His comment is not accurate in that there are plenty of theories, but the general idea behind the claim is far more accurate than what probably many that frequent HN believe about long COVID. Long COVID is poorly understood and the research around it has overall been inconclusive, and much of it very low-quality: https://vinayprasadmdmph.substack.com/p/long…

> Long COVID is poorly understood and the research around it has overall been inconclusive

This is far from the truth. Over 400 long covid publications a month for the last couple years. Science has pushed this forward to be more conclusive and defined.

Covid contrarians like Vinay are nothing but minimizers with MDs. They cherry pick what serves their narrative while ignoring the rest.

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#129

Post by PathOfEclipse »

thenerdhead wrote: post #128
PathOfEclipse wrote: post #113

Earlier quoted context omitted.

Thanks for pointing me to that comment so I could upvote it. His comment is not accurate in that there are plenty of theories, but the general idea behind the claim is far more accurate than what probably many that frequent HN believe about long COVID. Long COVID is poorly understood and the research around it has overall been inconclusive, and much of it very low-quality: https://vinayprasadmdmph.substack.com/p/long…

> Long COVID is poorly understood and the research around it has overall been inconclusive This is far from the truth. Over 400 long covid publications a month for the last couple years. Science has pushed this forward to be more conclusive and defined. Covid contrarians like Vinay are nothing but minimizers with MDs. They cherry pick what serves their narrative while ignoring the rest.

I like how you couldn't be bothered to provide a single citation or reference to back up anything you just said. If I wanted to learn how I am wrong, you certainly failed to deliver.

> Over 400 long covid publications a month for the last couple years.

Let's just assume that statement is true. I said nothing about the quantity of research on long COVID; I said it was inconclusive and largely low-quality. If anything, your factoid could support my "low quality" assertion given how little benefit has been derived from said research.

Re: Low serotonin levels might explain some Long Covid symptoms, study proposes

#130

Post by thenerdhead »

PathOfEclipse wrote: post #129
thenerdhead wrote: post #128

Earlier quoted context omitted.

> Long COVID is poorly understood and the research around it has overall been inconclusive This is far from the truth. Over 400 long covid publications a month for the last couple years. Science has pushed this forward to be more conclusive and defined. Covid contrarians like Vinay are nothing but minimizers with MDs. They cherry pick what serves their narrative while ignoring the rest.

I like how you couldn't be bothered to provide a single citation or reference to back up anything you just said. If I wanted to learn how I am wrong, you certainly failed to deliver. > Over 400 long covid publications a month for the last couple years. Let's just assume that statement is true. I said nothing about the quantity of research on long COVID; I said it was inconclusive and largely low-quality. If anything,…

https://www.ncbi.nlm.nih.gov/research/coronavirus/docsum?fil...

https://academic.oup.com/nar/article/51/D1/D1512/6814452

In his video on the paxlovid trials he doesn't even know what the arm sizes are. Let alone take a minute to read the trial designs:

> The placebo includes ritonavir, which does not have an effect on the virus, but will help ensure people don’t know whether they are in the Paxlovid or placebo group.

https://medicine.yale.edu/cii/research/paxlc-study/

I don't care to further argue with you. I used to like Vinay, for what it is worth. But not anymore.

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