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Daily energy expenditure through the human life course

research.brighton.ac.uk

11–20 of 256 posts

Re: Daily energy expenditure through the human life course

#11
post #8

Super useful outcome, especially given I find that people think that after reaching even young ages 24, 25 even begin thinking that metabolism has some extreme drop off right after reaching young adulthood

Such rumors are created and spread by people who want an excuse rather than a solution. This wont help them since they want to cling to their excuses, but it can help others ignore those rumors.

I found the misconception useful because it prompted me to invest time in improving my diet in my 20s, before it was too late. Even if my metabolism has stayed the same since then, the no-vegetables-or-fruits approach would have caught up with me at the same time "low metabolism" would.

Re: Daily energy expenditure through the human life course

#13
This was completely expected, at the macro level this is easily observed by measuring the outputs of metabolism and bodily function, mainly heat and physical activity. All humans have a baseline bodily temperature, meaning that the inner metabolism also is the same across all humans.

Re: Daily energy expenditure through the human life course

#14

Super useful outcome, especially given I find that people think that after reaching even young ages 24, 25 even begin thinking that metabolism has some extreme drop off right after reaching young adulthood

According to the paper this is "Fat-free mass-adjusted expenditure", and testosterone DOES start to slowly decline after around age 25. The trouble people have with starting to gain weight easier as they enter their 30s and 40s is caused by this since they'll lose muscle mass as such hormones decline, which causes fat gain assuming similar food intake and activity levels, this effect is not included by adjusting for fat-free mass.

Re: Daily energy expenditure through the human life course

#15

Another sobering result for the fitness industry, that convinces 30 year old men to be on TRT.

TRT is great for people who have true hypogonadism that can’t be fixed by other means. I had a friend growing up whose testosterone was under 100ng/dL no matter what he tried with his doctor. Finally got TRT and felt normal again.

However, after the honeymoon period the experience made him realize that not everything is explained and fixed by testosterone. He still had some mental health issues, he still had to work for gains at the gym, wasn’t suddenly full of boundless motivation. All this despite being put toward the upper end of the range for a long time.

This seems to be playing out with a lot of young people going to TRT clinics: The TRT clinics are prescription writing factories that will find an excuse to give almost anyone TRT. They make claims that the normal ranges are wrong and the only correct result is to be at the top of, or above, the reference range. They start people on insane beginning doses like 250mg/week because it gives them a rush to feel like it’s “working”, especially before their natural production shuts down.

The clinics also try to lock people into getting their prescriptions from the clinic in a subscription model. They basically get people hooked, literally dependent on testosterone because their endogenous production has shut down, and then require them to order the testosterone through their pharmacy to continue receiving the prescriptions. If they go to a family doctor, the family doctor will probably decline to continue writing such high dose prescriptions because high doses generate significant side effects, so the person returns to the TRT clinic.

It’s really bad out there. I think we’re headed for tighter regulation of these clinics soon, or at least I hope so. Every time I listen to the radio I get several ads for different clinics every hour promising men they will lose weight, be better in bed, have more energy, conquer the world.

Re: Daily energy expenditure through the human life course

#16
post #10

Earlier quoted context omitted.

I agree with your observation, but at the same time, I do think that what a lot of these people might be expressing is their observation of the disconnect between their socially implanted expectations (you're an adult when your 18/21! you are now -mature-), and their experience reality. Which is that for many (most?) people who go through the typical North American education pipeline through university/college (and I…

I some times make the following observation: When I was 15, I thought I had grown up quite a lot and looked back on my 10-year old self as someone who was just getting started. When I was 20, I thought I had grown up quite a lot and looked back on my 15-year old self as someone who was just getting started. When I was 25, I thought I had grown up quite a lot and looked back on my 20-year old self as someone who was j…

[deleted]

Re: Daily energy expenditure through the human life course

#17

Super useful outcome, especially given I find that people think that after reaching even young ages 24, 25 even begin thinking that metabolism has some extreme drop off right after reaching young adulthood

According to the paper this is "Fat-free mass-adjusted expenditure", and testosterone DOES start to slowly decline after around age 25. The trouble people have with starting to gain weight easier as they enter their 30s and 40s is caused by this since they'll lose muscle mass as such hormones decline, which causes fat gain assuming similar food intake and activity levels, this effect is not included by adjusting for…

I also think 30-40 is more likely caused by life just being more complicated! Juggling kids is basically a full time job, and many families are two income families. Hard to hit the gym when your child, who cannot be left alone, increases your effective work hours to 80-90/week minimum no vacation no breaks.

Re: Daily energy expenditure through the human life course

#18
This doesn't seem to line up anecdotally;

The first outlier I see is female health and PCOS, starting in mid 20s for women.

The next outlier I see is insulin resistance and pre and diabetes based metabolism decline.

From a hormone perspective, nose, ear, chin (femalr), and head hair seem to be going under significant change.

Re: Daily energy expenditure through the human life course

#19
post #13

This was completely expected, at the macro level this is easily observed by measuring the outputs of metabolism and bodily function, mainly heat and physical activity. All humans have a baseline bodily temperature, meaning that the inner metabolism also is the same across all humans.

"Humans are spherical cows"

Re: Daily energy expenditure through the human life course

#20

Another sobering result for the fitness industry, that convinces 30 year old men to be on TRT.

TRT is great for people who have true hypogonadism that can’t be fixed by other means. I had a friend growing up whose testosterone was under 100ng/dL no matter what he tried with his doctor. Finally got TRT and felt normal again. However, after the honeymoon period the experience made him realize that not everything is explained and fixed by testosterone. He still had some mental health issues, he still had to work…

I had low testosterone due to a brain injury, and going on TRT was absolutely life changing. I do wonder if it could be largely beneficial for older men in the same way hormone replacement therapy for post menopausal women is.

That said, permanently messing with your hormones as a younger person for no good reason is insane and I would try to talk anyone I knew out of it.

Fun fact: I had an endocrinologist at the University of Minnesota medical clinic tell me that going on TRT wouldn’t affect my fertility. Cue IVF 8 years later…

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