Live data from Hacker News

Gene-Engineered Mouth Bacteria

lanternbioworks.com

161–170 of 312 posts

Re: Gene-Engineered Mouth Bacteria

#161
post #17

Earlier quoted context omitted.

Tooth decay or brain and liver damage? Or reducing sugar?

Our body can assimilate 1 Alcoholic Unit per day without any problems. I doubt those bacteria would produce anything in that order of magnitude so I truly don't understand your reply. Did you just blindly write: "alcohol therefore bad"?

Unless it gets past the stomach, into the intestine and ferments most of the carbs you eat instead of traces of the carbs ingested

Re: Gene-Engineered Mouth Bacteria

#162

Earlier quoted context omitted.

It seems hard to believe the ethanol producing bacterial strain would dominate your oral microbione for life from one application. But I’m willing to have an open mind and see some data. They need to get the data off of the Google drive and presented in a better way. I don’t click unknown Google drive links if I can avoid it.

Brushing your teeth and using mouthwash wipes out the majority of the micro biome. Application of the new strain shortly after could totally replace it wholesale. That said, I can’t imagine there’s not other side effects that just aren’t known yet. The sample size and reporting (as far as we know) is just too small and meaningless.

Does brushing and mouthwash really eliminate your microbiome? I heard it does precious little. Most of the microorganisms live below the gumline and surfaces. If that were true it would eliminate caries! Please post links

Re: Gene-Engineered Mouth Bacteria

#163

This is certainly an interesting idea, but there's absolutely no way for anyone to judge whether the claim on this page is bulletproof true, something plausible worth researching more, or just total nonsense. But the fact that there isn't a single link to any scientific paper or evidence whatsoever, or even a single person's name linked to the site (or source of funding or anything ), makes me assume this is just spa…

[deleted]

Re: Gene-Engineered Mouth Bacteria

#164
post #160
post #97

Earlier quoted context omitted.

Patent hell should be over if this was invented in 1985.

who knows. maybe invented as a concept and then developed as a concrete dentistry protocol, which then got parented recently?

Good point. But that would be odd then to present it as solved in 1985 if only recently was figured out how to put it into a protocol. That would be a new innovation rather than “been around forever but never used.”

Re: Gene-Engineered Mouth Bacteria

#165

Earlier quoted context omitted.

Water also just dissolves the sugar and reduces the amount sitting in and on our teeth. I do this same thing and haven’t had a cavity in a very long time.

Is the rinsing needed, strictly speaking? Is there something special about spitting the water out afterwards instead of e.g. swallowing it?

Who said they spat it out? Rinse doesn’t necessarily imply spitting something out. You spit out mouth wash after rinsing because you can’t drink mouth wash. But sugary water is something you can drink.

Re: Gene-Engineered Mouth Bacteria

#166

Earlier quoted context omitted.

Ray Kurzweil will outlive us all, if taking 200 pills a day works: https://www.wired.com/2008/03/ff-kurzweil/#:~:text=He%20is%2... .

I just cant take this seriously. Why are Americans so afraid of death?

I don't subscribe to his belief system, but logically if you enjoyed life, why wouldn't you want to prolong it?

Re: Gene-Engineered Mouth Bacteria

#167

"This has, to our knowledge, caused no ill effects since." That's the kicker. Damn near everything has side effects. How and why the FDA approves some things but not others is a quagmire, but the truth is that almost everything has side effects. Sometimes it feels like every approved drug ad you see on TV will have some lawsuit 20-30 years later. Look at where we are right now with ozempic. We know one of the side ef…

Ozempic and thyroid cancer? Not really.

https://healthnews.com/news/possible-thyroid-cancer-risks-wi...

Re: Gene-Engineered Mouth Bacteria

#168
post #135

Earlier quoted context omitted.

$20k per dose Jesus H Christ. Rent seeking galore. Hopefully the patent has run out by now and others can get in on the action and make it affordable. There’s no way in hell this could possibly cost $20k. Is capitalism ever going to produce innovation that’s affordable to regular people again and not just benefiting the profiteering VC parasite class?

> Hopefully the patent has run out by now and others can get in on the action and make it affordable. The patent has run out, and in the ~20y since it expired no one has tried to revive the idea. Why are you faulting the people who are finally picking the idea back up instead of all the people who could have but didn't over the last ~20y?

I’m faulting them because it’s nothing more than a get rich quick scheme. Another comment even noted they are slightly tweaking it so they can get another patent for it.

The government should be funding this and making it available to the general population at an affordable price instead of just having the free market “figure it out” and making something affordable only to the ultra rich. But the US is a country where the government isn’t allowed to do anything and everything has to be left to the free market which nowadays is nothing more than a bunch of hyper capitalistic rent seekers that are only interested in maximizing profit at the expense of everyone else.

Re: Gene-Engineered Mouth Bacteria

#169
post #34

Probiora seems similar, but less sticky (it recommends a daily dissolvable tablet instead a once a decade tablet) and instead of producing ethanol, produces hydrogen peroxide. https://probiorahealth.com/product/probiora/

Interesting product, but the site has one of the worst GDPR controls ive seen - silently redirects to Google if you attempt to view the site from an EU IP address. Thought my computer is going nuts

Australia as well.

Re: Gene-Engineered Mouth Bacteria

#170

A conversation with my friend who was a dentistry student, ~2013. > [The friend, let's call her L, trying to dissuade me from drinking some fizzy drink] > J: But I won't get a cavity if the liquid doesn't touch my teeth. > L: Cavities are caused by the ensuing low ph environment, not by contact with teeth > J: Does that mean I can drink as much of it as I want as long as I rinse my mouth with water afterwards? > L, w…

I pretty much stopped getting cavities when about 10 years ago I stopped enjoying sweet foods and drinks. (Dessert, pastries, juice, soda, etc)

Yes I understand that refined breads, such as white bread on sandwiches, will still cause tooth decay; but I found simply drastically cutting down sugary foods & drinks was enough.

Post reply on HN