21–30 of 257 posts
Earlier quoted context omitted.
At least I get eggs from a neighbor and not “big egg”; I keep thinking about getting my own chickens but that’s not the way I want to feed Mr. Fox who lives in my neighborhood too.
Well, your free range chickens aren't truly free range if they don't have to fend off the occasional (and free range) fox! Nothing is more natural and free range than the occasional murder between animals.
"For more than 150 trials, Carlisle got access to anonymized individual participant data (IPD). By studying the IPD spreadsheets, he judged that 44% of these trials contained at least some flawed data: impossible statistics, incorrect calculations or duplicated numbers or figures, for instance. And in 26% of the papers had problems that were so widespread that the trial was impossible to trust, he judged — either bec…
Earlier quoted context omitted.
Both of those are substances that should be harmful based on the effects of the major ingredients: e.g. caffeine is addictive and when I am deprived of it my schizotypy flares up and I have paranoid episodes (I yell at my wife “why the hell are you always standing where I want to go next?”) I have had two doctors tell me three other reasons why I should quit. Look in the medical literature and it seems outright spamm…
Furan content in coffee too. Very low amount but still. Coffee prevents headaches for me so I'll always drink it. And no it's not related to physical dependence although at this point the withdrawal will guarantee a headache.
I often chuckle that same people who vehemently defend vaccine safety studies also decry studies that show processed seed oils, glyphosate, aspartame, and hundreds of other molecules or compounds are unsafe over time. That's the beauty of medical studies! Whether they're good or bad, your own biases mean you can simply ignore the ones that don't align with your opinions. Oh, before I forget! Red meat and saturated fa…
Do you think well-funded RCTs (like those that support vaccine safety) are just as weak as any old observational study?
While we're on the subject, how many studies period are faked or flawed to the point of being useless? It seems to me that the scientific community's reaction to the replication crisis has been to ignore it.
They've always known so there hasn't actually been any new information from which to spur action. In the academic circles I've run in there has always been a strong mistrust of reported results and procedures based on past difficulties with internal efforts replicating results. Basically a right of passage for a grad student to be tasked with replicating work from an impossible paper.
"For more than 150 trials, Carlisle got access to anonymized individual participant data (IPD). By studying the IPD spreadsheets, he judged that 44% of these trials contained at least some flawed data: impossible statistics, incorrect calculations or duplicated numbers or figures, for instance. And in 26% of the papers had problems that were so widespread that the trial was impossible to trust, he judged — either bec…
You don't need "big pharma" for this. Researchers at universities also do these kinds of things because it helps them advance their careers.
... into the multi-billion dollar companies GP is talking about.
While we're on the subject, how many studies period are faked or flawed to the point of being useless? It seems to me that the scientific community's reaction to the replication crisis has been to ignore it.
Those are two wildly different things. Most things are flawed. Deliberately fabricating results is anathema to advancing science.
Yes I work with these IPD spreadsheets every day and they all have typos often in the time/date column (issues with midnight and new years are very common) this can result in an erroneous reporting of something like average drug exposure or clearance if 1 or 2 subjects have uncaught errors in the reported data I would expect 26% or more studies have these flaws but faked data is a different thing entirely and 26% fak…
Earlier quoted context omitted.
At least I get eggs from a neighbor and not “big egg”; I keep thinking about getting my own chickens but that’s not the way I want to feed Mr. Fox who lives in my neighborhood too.
Well, your free range chickens aren't truly free range if they don't have to fend off the occasional (and free range) fox! Nothing is more natural and free range than the occasional murder between animals.