Live data from Hacker News

Chronic fatigue syndrome may have a post-viral infection origin

medicalxpress.com

271–280 of 348 posts

Re: Chronic fatigue syndrome may have a post-viral infection origin

#271

Earlier quoted context omitted.

Because 90 days is long enough to see results for most people, but not so long that it's an impossible time frame. Because drinking 10 lbs of vegetables is doable, but eating them is almost impossible raw. If you cook them, it's still hard to eat 10 lbs of vegetables and you've killed a lot of nutrients. Because it gives your body a break from digestion. You'll feel a lot better. Edit: even those that think the idea…

> You'll feel a lot better. But you don't say why and how it's relevant to the topic at hand. Anybody can come up with "eat vegetables". "Eat food. Not too much. Mostly plants."

Almost every human on earth has come up with 'eat vegetables', correct.

1, most people don't enough of it anyway.

2, I didn't say I came up with. I said I think a massive dose of vegetables for 90 days, that are ultra easy to digest because most fiber has been removed, is beneficial.

3, I didn't say mostly plants. I said all plants. If you try to do that, you'll have a LOT of trouble getting 1000+ calories doing it. Juicing them makes it possible.

But to your first point.. this thread was about people feeling terrible for months after an infection. We don't even know how or why they feel terrible. My advice was to try juicing vegetables, and not eating anything else, for 90 days. Because it has made MANY people that have tried it into believers.

Out of people that have tried it, I'd say 40% think it's a miracle process, 50% think it's very good for you, and 10% think they didn't feel any different.

Out of people that haven't tried it, 10% believe it would be great for them but they dont have the willpower to try it. The other 90% are usually negative about it without really having any good explanation.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#272
post #181

Earlier quoted context omitted.

Machine learning doesn't actually work very well for that. Attempts to apply it as you suggest in medical research have mostly not produced clinically useful results. More basic research into root causes is the only approach that is likely to lead to truly effective treatments.

Could you please explain it’s limitations/constraints for this use case.

The data is crap. Patient reported data is notoriously unreliable. Even data reported by clinicians is highly inconsistent between organizations so it takes a huge cleansing and normalization effort to get anything usable for clinical research. Applying ML to it tends to find a bunch of spurious correlations that aren't clinically actionable.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#273

Earlier quoted context omitted.

It's an issue when doctors deny it. For many years, for many doctors, that was the case with CFS.

There is still no identified viral mechanism for CFS. So yes, you will continue to find many doctors that deny that there is convincing evidence for viral causes of CFS because that is the reality of the current situation.

Doctors are not medical forensics. It shouldn't matter that the mechanism behind CFS isn't known, there's ample evidence that the condition is real. So I reject that casual dismissal.

However, there is no known way to treat CFS. That problem is a much more valid excuse for a doctor to do nothing. But a doctor that refuses to acknowledge a patient's troubles because they don't know how to treat it is a bad doctor.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#274
post #202

Earlier quoted context omitted.

Isn’t this the diet that killed Steve Jobs?

I think that was the cancer.

It's been widely speculated that his extreme diet is likely what caused or contributed to his pancreatic cancer. Supposedly he was also ignoring his doctor's medical advice and had some irrational belief that his fruit diet would cure his cancer.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#276
post #274

Earlier quoted context omitted.

I think that was the cancer.

It's been widely speculated that his extreme diet is likely what caused or contributed to his pancreatic cancer. Supposedly he was also ignoring his doctor's medical advice and had some irrational belief that his fruit diet would cure his cancer.

It's also been speculated that the cancer was from his early days at HP soldering.

But that was only a doctors opinion based on the doubling rate of the cancer.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#277
post #112

Physician here. Imo CFS is best understood as the endpoint of an evolution within the nervous system that is increasingly called "central sensitization syndrome." (CSS) This syndrome is caused by a chronic dissociative or avoidant stress response, usually having it's origin in early childhood adversity. Prior to developing CFS, most individuals have other manifestations of CSS, such as IBS, chronic pain, TMD, etc. Ev…

Hmm. The argument is that it lies within the nervous system (physically), but then you mention avoidance/dissociation (psychological)? This reminds me of a lot of physical/psychological/"it's all in your head" discussions with various sorts of CFS sufferer, most of whom have serious problems getting anyone to take seriously the possibility that it might not be all in your head. https://www.cfsselfhelp.org/pacing-tuto…

[deleted]

Re: Chronic fatigue syndrome may have a post-viral infection origin

#278

Earlier quoted context omitted.

Thank you! Seems like there are both positive small studies and self-reported anecdata available https://reddit.com/r/covidlonghaulers/s/2SzkM5ca5K https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250701/

That "study" doesn't even have a control but, then again, I wouldn't expect much from research around long covid.

Really hard to get proper funding for LDN. It is an already incredibly cheap drug in a minute dose... this treatment is not exciting to anyone except patients and a few passionate researchers.

Lots of studies showing "interesting results, needs more investigation" but high quality studies are very slow to come...

Re: Chronic fatigue syndrome may have a post-viral infection origin

#279
post #181

Earlier quoted context omitted.

Machine learning doesn't actually work very well for that. Attempts to apply it as you suggest in medical research have mostly not produced clinically useful results. More basic research into root causes is the only approach that is likely to lead to truly effective treatments.

Could you please explain it’s limitations/constraints for this use case.

If you gave me a 300 question health questionnaire on 15 occasions, spaced by several weeks each, you would likely get at least 3,000 unique answers.

Re: Chronic fatigue syndrome may have a post-viral infection origin

#280
post #189

I did not get covid but did get the vaccines + 2 boosters. I have been feeling tired etc for the last 6+ months turns out because of the work at home etc and my lifestyle I was not getting enough sunlight and had very low vitamin D levels. I am not white so need to spend longer time in sunlight according to my doctor.

Unless you've been getting weekly tests you can't be sure that you haven't been infected with SARS-CoV-2. Many infections are asymptomatic. You might not have noticed at the time.

unlikely you need to meet people to get infected I work in very small firm of 6-7 people and live in a city where the spread was effectively controlled and rapidly vaccinated unlike most countries though it is not impossible. I am not a very social person hence the lack of sunlight.
Post reply on HN