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The anesthetic effect of air at atmospheric pressure

pubmed.ncbi.nlm.nih.gov

91–100 of 205 posts

Re: The anesthetic effect of air at atmospheric pressure

#91
post #79
post #65

Earlier quoted context omitted.

Yikes, I just checked, and Captain Morgan's is 35% Alcohol. I'm aware of Bacardi 151 (75.5% alcohol) which is like fire water to me. Can't imagine drinking something so concentrated regularly.

The only reason I'd ever buy everclear (95% ethanol) is for cleaning optics.

It's also great for doing various tinctures/extractions if you get into the more exotic side of cooking/food/mixology

Re: The anesthetic effect of air at atmospheric pressure

#92
post #76

Earlier quoted context omitted.

neuroscientists are just mad that "gut feeling" is actually the truth, and we're generally being manipulated by the billions of microbes in our guts. Simple example: why do people crave cake when they're on a diet that doesn't allow cake? There are microbes that convert stuff in grasses (corn, etc) into opioids. Opioids are great, make us feel great, and if we are used to having opioids and suddenly stop, we go into…

Huh? Relevance? This has nothing to do with the biophysics of action potentials.

"neuroscientists" and the like go deep in the weeds with what/how different chemicals interact with cells, neurons, etc; but in general i don't read a lot of papers that try to answer "why". Scientists studied automobiles and discovered that applying pressure to a lever in the car causes the motion of the car to slow and possibly stop. End of paper, we proved cars stopped when we put pressure on a lever. No mention of friction anywhere.

I've been balking about this since at least 2006-2007 online and in person, and it took about a decade for studies that showed "why", not just "how/what". Then again, most people don't know that our bodies have dedicated receptors for nicotinoids, cannibinoids, opioids. Most people also don't know that tomato ketchup has nicotine in it, or that nearly all grasses contain the precursors to opioids in them. Once your intestines get a substance, nearly all bets are off as to what comes out, at what rate, and what volume.

So, essentially, that neuroscientists disagree isn't novel. They're laser focused on the post hoc, rather than the cause(s).

Re: The anesthetic effect of air at atmospheric pressure

#93
post #79
post #65

Earlier quoted context omitted.

Yikes, I just checked, and Captain Morgan's is 35% Alcohol. I'm aware of Bacardi 151 (75.5% alcohol) which is like fire water to me. Can't imagine drinking something so concentrated regularly.

The only reason I'd ever buy everclear (95% ethanol) is for cleaning optics.

Good solvent for shellac as well, without the nasty smell and headache from denatured alcohol fumes. Costs more though, since it’s sold and taxed for consumption.

Re: The anesthetic effect of air at atmospheric pressure

#95
post #68
post #50

Earlier quoted context omitted.

"We’re basically continuously narked, we’re just so used to it we don’t even know." Just because one direction on the gradient means that we respond in a way that looks like a narcotic does not mean that the other direction will respond in the opposite manner. I'm sure the nootropics folks would have discovered being super not high by now if it were as easy as breathing a mixture that doesn't have nitrogen in it.

You'd hope mind-hackers would've explored & confirmed/refuted/quantified the effect, but stuff like this often lies underexplored for decades, despite hints like this 1975 study – which actually shows the 'gradient' of clearer thinking continues in the other direction, no hand-wavy extrapolation required. It's what they found! In 1975! How long did it take for society to fully recognize, & remediate, the effects of e…

Expense report: scuba regulator for "deep work" sessions.

Re: The anesthetic effect of air at atmospheric pressure

#96
post #85

Earlier quoted context omitted.

All you need is zeolite crystals and a compressor. Zeolite fixes nitrogen under pressure, so you can use it to separate nitrogen from oxygen. This is how those "oxygen concentrators" work. I'm sure you get can hold of a relatively-cheap chinese one, they don't have dangerous parts or controlled substances. But it wouldn't be that hard to build one from scratch either. https://www.aliexpress.com/w/wholesale-oxygen-con…

> Sorry, your search "oxygen concentrator" did not match any products. Please try again. i thought it might be because of the /w/wholesale path, so i went to aliexpress (i have an account) and searched on the main page, and it gave the same result. Curiously, "oxygen concentrat" as the search term brings up alleged devices. This dovetails with my very short comment that such devices are hard to find without prescript…

AliExpress search is kinda wonky, it sometimes just breaks for a bit on specific search terms, or maybe it'll work but only for certain sort orders.

The link is giving search results for me (although admittedly I'm not in the US, so if they're doing any country-specific filtering for US clients I wouldn't know about it).

Re: The anesthetic effect of air at atmospheric pressure

#97
post #65

Earlier quoted context omitted.

Grog was at least 10% alcohol, plus lime juice. Navy rum was 65% or 130 proof. That's more than enough to inhibit most waterborne diseases such as cholera (inhibited in wine at 6.25% abv, though wine has tannins and phenols).

Yikes, I just checked, and Captain Morgan's is 35% Alcohol. I'm aware of Bacardi 151 (75.5% alcohol) which is like fire water to me. Can't imagine drinking something so concentrated regularly.

Few people are regularly pounding rum shots.

Re: The anesthetic effect of air at atmospheric pressure

#98
post #79

Earlier quoted context omitted.

The only reason I'd ever buy everclear (95% ethanol) is for cleaning optics.

Good solvent for shellac as well, without the nasty smell and headache from denatured alcohol fumes. Costs more though, since it’s sold and taxed for consumption.

I can't practically get everclear since I live in California, where it's illegal. I use 99% IPA for shellac, it's not denatured but you wouldn't want to drink it anyway.

Re: The anesthetic effect of air at atmospheric pressure

#99
post #79
post #65

Earlier quoted context omitted.

Yikes, I just checked, and Captain Morgan's is 35% Alcohol. I'm aware of Bacardi 151 (75.5% alcohol) which is like fire water to me. Can't imagine drinking something so concentrated regularly.

The only reason I'd ever buy everclear (95% ethanol) is for cleaning optics.

Fun fact: Vodka is usually distilled to a high purity close to everclear using a reflux still, then diluted with water to get down to 40%.

Re: The anesthetic effect of air at atmospheric pressure

#100

Earlier quoted context omitted.

as siblings commented, pure oxygen gets you high. a couple of breaths of pure oxygen will relieve pain and induce euphoria. I am not entirely clear on the definition of "narcotic" so i may be being redundant. My issue, though, is i can't find a way to safely generate oxygen for a decent price. I know electrolysis works, but these atomic sieves look safer. They're also difficult to acquire without a prescription, at l…

Someone else in this thread mentioned diving. When I was doing my advanced open water course, we did an exercise to demonstrate nitrogen narcosis. Super simple test: we had a card with the numbers 1-16 written on a 4x4 grid in random order. You have to tap the numbers in order and it’s a timed exercise. We did it on the surface in the boat and again at 30m depth; my performance was maybe 20% slower, my buddy was more…

Wouldn't being underwater make you slower just due to the extra resistance of water vs air?
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