So is the suicide rate at higher elevations due to people being generally less doped up?
The anesthetic effect of air at atmospheric pressure
81–90 of 205 posts
Re: The anesthetic effect of air at atmospheric pressure
#82Anecdotally, as a mountaineer, I love the effect of a little less atmospheric pressure. Not loads less, above 3000m it starts getting inconvenient. But 1000-2000m my mind feels more clear and focused than at sea level. I wonder if this is related?
I feel the same effect at 400m, and... well, I'm certain there's no physical effect involved.
It's just that the mountain I most usually hike on is 400m high from its sea-level base.
Re: The anesthetic effect of air at atmospheric pressure
#83Earlier quoted context omitted.
Cake does not generally contain grasses...and if it were true that there were trains of gut flora that converted sugars to opioids almost everyone in America would live in a perpetual state of intoxication. Sugar withdrawal is also not even remotely similar to opioid withdrawal.
Cake usually contains flour, which is made from wheat, which is a form of grass...
No, wheat is made from the seeds, i.e., the grain, of wheatgrass, not the grass.
That some bacteria are able to eat the cellulose or other cells in grass is absolutely unrelated to their ability to consume the completely different structures and nutrients in a seed.
Re: The anesthetic effect of air at atmospheric pressure
#84How fast could you watch youtube videos if you switched to helium?
Re: The anesthetic effect of air at atmospheric pressure
#85Earlier quoted context omitted.
"We’re basically continuously narked, we’re just so used to it we don’t even know." Just because one direction on the gradient means that we respond in a way that looks like a narcotic does not mean that the other direction will respond in the opposite manner. I'm sure the nootropics folks would have discovered being super not high by now if it were as easy as breathing a mixture that doesn't have nitrogen in it.
as siblings commented, pure oxygen gets you high. a couple of breaths of pure oxygen will relieve pain and induce euphoria. I am not entirely clear on the definition of "narcotic" so i may be being redundant. My issue, though, is i can't find a way to safely generate oxygen for a decent price. I know electrolysis works, but these atomic sieves look safer. They're also difficult to acquire without a prescription, at l…
All you need is zeolite crystals and a compressor. Zeolite fixes nitrogen under pressure, so you can use it to separate nitrogen from oxygen. This is how those "oxygen concentrators" work. I'm sure you get can hold of a relatively-cheap chinese one, they don't have dangerous parts or controlled substances. But it wouldn't be that hard to build one from scratch either.
https://www.aliexpress.com/w/wholesale-oxygen-concentrator.h...
Re: The anesthetic effect of air at atmospheric pressure
#86> It concluded that the nitrogen in ambient air slightly but measurable impairs human performance
So would a modified cabin air mix improve the performance of pilots?
Re: The anesthetic effect of air at atmospheric pressure
#87Earlier quoted context omitted.
Cake usually contains flour, which is made from wheat, which is a form of grass...
No, wheat is made from the seeds, i.e., the grain, of wheatgrass, not the grass. That some bacteria are able to eat the cellulose or other cells in grass is absolutely unrelated to their ability to consume the completely different structures and nutrients in a seed.
sugar is a grass, or corn syrup, which is from a grass...
edit: also opiate and opioid are different, i'm talking about the brain chemical, not the drug.
Re: The anesthetic effect of air at atmospheric pressure
#88Earlier quoted context omitted.
as siblings commented, pure oxygen gets you high. a couple of breaths of pure oxygen will relieve pain and induce euphoria. I am not entirely clear on the definition of "narcotic" so i may be being redundant. My issue, though, is i can't find a way to safely generate oxygen for a decent price. I know electrolysis works, but these atomic sieves look safer. They're also difficult to acquire without a prescription, at l…
All you need is zeolite crystals and a compressor. Zeolite fixes nitrogen under pressure, so you can use it to separate nitrogen from oxygen. This is how those "oxygen concentrators" work. I'm sure you get can hold of a relatively-cheap chinese one, they don't have dangerous parts or controlled substances. But it wouldn't be that hard to build one from scratch either. https://www.aliexpress.com/w/wholesale-oxygen-con…
> Sorry, your search "oxygen concentrator" did not match any products. Please try again.
i thought it might be because of the /w/wholesale path, so i went to aliexpress (i have an account) and searched on the main page, and it gave the same result. Curiously, "oxygen concentrat" as the search term brings up alleged devices. This dovetails with my very short comment that such devices are hard to find without prescriptions, in the US.
Searching for similar things on amazon only brings up carrying cases and accessories for the "well known" brand(s) of oxygen concentrators. And for some reason both sites show results for these things that blow air in your face for whatever reason...
Re: The anesthetic effect of air at atmospheric pressure
#89Earlier quoted context omitted.
Grog was at least 10% alcohol, plus lime juice. Navy rum was 65% or 130 proof. That's more than enough to inhibit most waterborne diseases such as cholera (inhibited in wine at 6.25% abv, though wine has tannins and phenols).
Yikes, I just checked, and Captain Morgan's is 35% Alcohol. I'm aware of Bacardi 151 (75.5% alcohol) which is like fire water to me. Can't imagine drinking something so concentrated regularly.
If I remember correctly, the lower ranking navy members weren't even allowed access to the strong stuff. Only the officers who had to dilute it before giving it to the others.
Re: The anesthetic effect of air at atmospheric pressure
#90The action potential is an electrical manipulation of reversible abrupt phase changes in the lipid bilayer. Normally the lipid bilayer is in a liquid phase but the the switching out of monovalent sodium for bivalent calcium ions changes the number of phospholipid carboxyl head groups each ion is electrostatically associated with. This changes the heat capacity and causes the lipid membrane to become a solid/gel phase…
Yeah, physician (pathologist, specifcally) with a degree in physics here. I'm going through articles in other tabs right now just because I'm skeptical enough to consider crazy ideas (always good to build bulwarks), this is, at best hypothetical, but mainly the chain of causality in the above statements is a hot mess.
I spend a lot of time looking at cell membranes. More than almost all of humanity. The naive Fluid Mosaic Model is certainly incomplete, but let's let Dr. Nicholson himself (the author of the original description) have a chance to provide his update first (1). So, yes, there's lot of other stuff going on, but certainly the basic organizing concepts are intact.
I'll allow the idea that the transfer of ions across the membrane is a thermodynamic effect. Of course it is. The whole nitrogen vs helium thing works well enough in my mind with just "thermodynamics". Yeah, sure.
But this statement "The action potential itself is the propagation of this solid phase" does not pass the sniff test for me. The action potential is a self-propagating electric field tripping channels along the way, propagating along inner and outer surfaces of the membrane, the channels are what make it self-propagating. Nothing about the concept of "solid" makes sense at these scales in a biological system. Everything is just more or less bound, and that neighbor-to-neighbor binding is entirely secondary to the mammoth electrical field whipping down the axon.
(1) Nicholson GL, de Mattos GF. A Brief Introduction to Some Aspects of the Fluid–Mosaic Model of Cell Membrane Structure and Its Importance in Membrane Lipid Replacement. 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708848/