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FDA Approves First Oral Treatment for Postpartum Depression

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Re: FDA Approves First Oral Treatment for Postpartum Depression

#22

Earlier quoted context omitted.

Or , a helpful drug that helps people in a risky situation.

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I like how you start of with something substantiated, and then follow it with something fringe and unsubstantiated

Please tell me you’re at least selling coffee mugs to your flock

Re: FDA Approves First Oral Treatment for Postpartum Depression

#24
I wonder how much of post-party depression is caused by isolation.

In the past, new mothers were surrounded by a whole village of women who would help care for the woman and the baby.

Many times now, women are isolated with maybe the father present. And even then there are pressures to get back to work.

This isn’t to discount or minimize postpartum depression, but if we as a society set up people for failure which require them to take a pill to get better, maybe something needs to be rethought.

Re: FDA Approves First Oral Treatment for Postpartum Depression

#25
post #18

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For 99.9999% of humanity's history, penicillin was "never needed".

Antidepressant usage is universal throughout Europe. It makes more sense to treat postpartum depression, not less, because it's so likely to have a straightforward chemical cause. That's why there is an oral treatment specifically targeting it.

Re: FDA Approves First Oral Treatment for Postpartum Depression

#26
post #18

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Postpartum depression is much lower in places where mothers get a lot of sunshine, live among numerous family and friends, eat whole diets, walk a lot, and don't suddenly go from rat-race identity-capturing careers to soloing a screaming infant inside all day.

I'm not saying PPD is non-existent in those societies, just that in western societies like the US I'm more surprised when new mothers don't get PPD than I am when they do.

Re: FDA Approves First Oral Treatment for Postpartum Depression

#27

Earlier quoted context omitted.

[flagged]

I like how you start of with something substantiated, and then follow it with something fringe and unsubstantiated Please tell me you’re at least selling coffee mugs to your flock

[flagged]

Re: FDA Approves First Oral Treatment for Postpartum Depression

#29
post #3

https://en.wikipedia.org/wiki/Zuranolone "An orally active inhibitory pregnane neurosteroid, zuranolone acts as a positive allosteric modulator of the GABAA receptor." Interesting. I was expecting another SSRI or something similar.

The inhibitory effect seems a bit surprising.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139029/#:~:tex....

https://en.wikipedia.org/wiki/Pregnanolone#Biological_functi...

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