Earlier quoted context omitted.
What, specifically, is different?
The machines are different. Multicore 64-bit chips are now standard for consumer PCs. RAM and persistent storage are faster and much more abundant. The architecture of the modern x86-64 is much more sophisticated than that of the 386 for which the earliest Linux was written. Vectorization, predictive branching, and asynchronous code are all front and center in the modern programmer's ecosystem. In short, hardware is…
The basic problem is that the kernel boundary is a trust boundary. You assume that anything in the kernel is legit and won't try to attack you, which simplifies things a lot. In the microkernel world the original idea was that all the servers would be just ordinary programs you could swap in and out at will. But then the threat model becomes muddied and unclear. Is it OK to run a server that's untrusted? If so, to what extent?
The Hurd seems under-designed as a consequence. To make that vision work you'd need to be willing to depart from UNIX way more, which really means being a research OS.