A New Mode of Cancer Treatment

#1

Post by atomroflbomber » Thu, Aug 03, 2023, 8:12 AM UTC

A New Mode of Cancer Treatment
science.org

Re: A New Mode of Cancer Treatment

#2

Post by lelag » Thu, Aug 03, 2023, 9:52 AM UTC

If 2023 ends up giving us AGI, room-temperature superconductors, Starships and a cure for cancer, I think we will able to call it a good year...

Re: A New Mode of Cancer Treatment

#3

Post by WithinReason » Thu, Aug 03, 2023, 9:55 AM UTC

lelag wrote: post #2

If 2023 ends up giving us AGI, room-temperature superconductors, Starships and a cure for cancer, I think we will able to call it a good year...

It's time we got compensated for the whole COVID thing

Re: A New Mode of Cancer Treatment

#4

Post by flobosg » Thu, Aug 03, 2023, 9:56 AM UTC

Not a medical chemist, but I noticed that three AOH1996 molecules are binding to PCNA. Would it make sense to chain together three AOH1996 molecules with flexible linkers for, I don't know, increased specificity or something like that?

Re: A New Mode of Cancer Treatment

#5

Post by [deleted] » Thu, Aug 03, 2023, 10:14 AM UTC

[deleted]

Re: A New Mode of Cancer Treatment

#6

Post by irdc » Thu, Aug 03, 2023, 10:21 AM UTC

flobosg wrote: post #4

Not a medical chemist, but I noticed that three AOH1996 molecules are binding to PCNA. Would it make sense to chain together three AOH1996 molecules with flexible linkers for, I don't know, increased specificity or something like that?

Maybe. But a bigger molecule will be less soluble and less capable of getting into the cell.

Re: A New Mode of Cancer Treatment

#7

Post by gadders » Thu, Aug 03, 2023, 10:58 AM UTC

WithinReason wrote: post #3

lelag wrote: post #2

If 2023 ends up giving us AGI, room-temperature superconductors, Starships and a cure for cancer, I think we will able to call it a good year...

It's time we got compensated for the whole COVID thing

[flagged]

Re: A New Mode of Cancer Treatment

#8

Post by treprinum » Thu, Aug 03, 2023, 11:07 AM UTC

lelag wrote: post #2

If 2023 ends up giving us AGI, room-temperature superconductors, Starships and a cure for cancer, I think we will able to call it a good year...

There is still the threat of WW3...

Re: A New Mode of Cancer Treatment

#9

Post by vazma » Thu, Aug 03, 2023, 11:07 AM UTC

lelag wrote: post #2

If 2023 ends up giving us AGI, room-temperature superconductors, Starships and a cure for cancer, I think we will able to call it a good year...

I think humanity deserves it after so many consecutive weird years

Re: A New Mode of Cancer Treatment

#10

Post by ImHereToVote » Thu, Aug 03, 2023, 11:15 AM UTC

gadders wrote: post #7

WithinReason wrote: post #3

Earlier quoted context omitted.

It's time we got compensated for the whole COVID thing

[flagged]

The US Federal government paid for the gain of function research under the Trump administration. This is still the most likely source for the novel part of the virus.