Earlier quoted context omitted.
Hair of the dog is a myth
Not if you never stop drinking!
Drink enough to wake up the next day still drunk and you're all good :)
Alcohol without the hangover – scientists are finding ways
291–297 of 297 posts
Re: Alcohol without the hangover – scientists are finding ways
#292The (main) problem with alcohol-free 'beer'/'wine'/etc. isn't the lack of drunkenness feeling? Especially beer has improved a lot but it's not there yet, I don't see how developing synthetic 'alcohol' will help when we still can't remove, or make the drink without causing, real alcohol? As for hormone shots to treat an already acquired hangover... It seems niche/less than ideal - I don't think many people would want…
I'm not a chemist, so this may be false, but I've heard it's almost impossible to make NA drinks that are very similar to the real thing. The reason I heard is that whilst ethanol has no flavor itself it does enable/carry (whatever that means) interactions between other chemicals meaning there are flavors present that will never be there without ethanol. Would love to know if that's actually true...
Very naively and also as not-a-chemist though I would think that just because that's how A drinks do it doesn't mean we can't achieve a NA drink with the same taste by a different mechanism?
I can't really think of a great example, but crisp (US: chip) flavours sometimes seem recognisable despite the actual ingredients being a concoction of a few not-what-the-flavour-is things.
Re: Alcohol without the hangover – scientists are finding ways
#293Earlier quoted context omitted.
Yeah you can certainly get in a state where your brain gets chemically unbalanced and addicted to the dopamine hit of a drink. I could never have one drink, once I'd had one my brain would want more and more and all logic would go out the window, it would be a death spiral until I blackout. Even though I'm a smart guy and know that will happen. I recently started on Naltrexone which is a opioid blocker which stops th…
I have naltrexone and while it’s no miracle drug it does help. I find it makes me feel weird and sick for 2-3 days after I take it, but it does help a lot with cravings. If you’re doing the Sinclair method you have to be really diligent to take it at least 45 minutes before your first drink or it won’t be as effective. If you take it daily you also are supposed to wear a bracelet since it effectively makes you immune…
Yeah I do the Sinclair method. I wasn't a daily drinker, it was once or twice a week socially, but it was unstoppable binge drinking.
It certainly works in my case. Now when I have another drink, I choose to do it, and it feels like I'm wading against water forcing myself to get it. Before, my brain would go on autopilot and order them automatically.
Re: Alcohol without the hangover – scientists are finding ways
#294[flagged]
Actually it’s been observed that some animals willingly seek fruits that have fallen and have started fermenting to get some buzz. Such animals don’t have an alcohol industry and a logistics network though.
And a few fermented fruits and a "buzz" are not a hangover. A hangover means you have overdone it.
Re: Alcohol without the hangover – scientists are finding ways
#295[flagged]
What's the purpose of live if you won't allow yourself to enjoy it a bit? So yeah, I'll do it, have fun and socialise with my friends. Of course within bounds, we're adults after all. I bet/hope there are less harmful alternatives out there but unfortunately there's not a lot research afaik on different chemicals.
I've actually enjoyed and done much more sober than I ever did during my entire drinking years.
But to stay on point, the original article is "Alcolhol without the hangover" - keyword "hangover". A hangover is a symptom you have overdone it, not just a few drinks with friends while socializing. It's more like, "I can't remember what we did after 6 beers and then shots", sort of mentality, and not eating or drinking enough water. That is when you have poisoned yourself.
40% of convicted murderers used alcohol before or during the crime.
70% of all drunk-driving fatalities were with drivers with a blood-alcohol level of 0.15%+.
Re: Alcohol without the hangover – scientists are finding ways
#296Earlier quoted context omitted.
This is on par with the trend of biohacking ... from ozempic, ADHD meds, transgender hormone therapies, to cheating hangovers ... You can't cheat nature, for long at least.
As someone who had their appendix removed yesterday, I’m grateful that cheating nature can actually be done safely and effectively.
Well, the appendix has gone from we don't know it's function, or it is a useless appendage, to it might have a role in our immune system [1].
[1] https://www.news-medical.net/health/Why-do-Humans-have-an-Ap...
Re: Alcohol without the hangover – scientists are finding ways
#297Earlier quoted context omitted.
NAC (N-acetyl-cysteine) is a precursor to glutathione, which is used up by your liver to break down the primary toxic metabolite of alcohol: acetylaldehyde. NAC is known as an OTC hangover "preventative," but don't take it chronically because it is a mucolytic and messes with other processes. Aside: as a non-alcoholic fermentation, kombucha contains a lot of acetylaldehyde, so avoid it during a hangover.
> Aside: as a non-alcoholic fermentation, kombucha contains a lot of acetylaldehyde, so avoid it during a hangover. Does that make kombucha bad for you?
I'm not sure, but it puts pressure on your liver if you combine it with alcohol since alcohol is also broken down into acetyl-aldehyde.