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Alcohol without the hangover – scientists are finding ways

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211–220 of 297 posts

Re: Alcohol without the hangover – scientists are finding ways

#211

Earlier quoted context omitted.

Alcohol and caffeine are the only two drugs I can think of (okay, in some circles maybe cannabis too) where the response to "I cut this thing out of my life" is often "why?" or "you know you could still do a little?" One exercise to illustrate the ridiculousness and disrespect of phrases like that is to replace "alcohol" with "crack". "I don't do crack anymore" would basically never be responded to with "you know, yo…

"Alcohol is humanity's oldest friend. How could I abandon a friend?" - Yang Wenli The difference is the huge influence alcohol has had on all human cultures throughout history. Yes, it's poison, but it's our poison.

Plus 1 to the LOGH reference using it as if it was real historical person who said that.

Re: Alcohol without the hangover – scientists are finding ways

#212
post #209

Earlier quoted context omitted.

* spending the evening playing video games that I've already spent a ton of hours on and am not getting any kind of new experience out of anymore * hanging out at a bar and talking to intoxicated people * house parties In exchange, new things are fun: * skateboarding * learning Japanese * building an arcade cabinet in my basement (I'm a software developer, very little experience with wood working and other hardware s…

* skateboarding * learning Japanese * building an arcade cabinet in my basement (I'm a software developer, very little experience with wood working and other hardware stuff) * waking up in the morning and being excited for the day I don't know about building an arcade cabinet, but all of these other things are both more fun and more efficient with alcohol. All of the Japanese I have learnt has been due to alcohol. Yo…

you sound insane

Re: Alcohol without the hangover – scientists are finding ways

#213
post #186

Alcohol without the hangover? What an invention! Scientists are working on this. I mean, other scientists devote their lives to fighting cancer, AIDS, heart disease. These guys go, "No, I'm focusing on hangovers. Oh, sure, thousands of people are dying needlessly, but this, ptooey. That's gotta stop. You ever try and watch football the next day? It's almost impossible. I'm devoting my life to that."

Ha! Nice riff on Seinfeld’s seedless watermelon bit! https://youtu.be/ZB39jT0qq3Y

Re: Alcohol without the hangover – scientists are finding ways

#214
post #18

Looks like a rebranding of GHB

I think you're right. I've always wondered why they don't water down GHB to be the equivalent of a low ABV drink. The only scary thing about GHB is its relative potency to volume. It's honestly a wonderful drug.

I presume it's down to the "therapeutic index" (how close a fun dose is to a dangerous dose) (although alcohol is much the same).

I agree it is a nice drug but one friend of mine did have his family stage an intervention because of his abuse of it.

Re: Alcohol without the hangover – scientists are finding ways

#216

There are many other alcohols, 2M2B( https://en.wikipedia.org/wiki/Tert-Amyl_alcohol ) for example, which are "alcohol without the hangover" in a sense. I seem to remember a scientist looking into ways to deliver these alcohols(absorbed in cellulose IIRC). You'll note that these chemicals, like alcohol, can also lead to overdoses and since they are much more potent it is even more difficult to ensure one does not ove…

I hope you can see that your friends are alcoholics. Drinking 18 of any alcoholic drink shouldn't be considered normal as much as the surroundings might indicate otherwise.

Re: Alcohol without the hangover – scientists are finding ways

#217

Earlier quoted context omitted.

Alcohol and caffeine are the only two drugs I can think of (okay, in some circles maybe cannabis too) where the response to "I cut this thing out of my life" is often "why?" or "you know you could still do a little?" One exercise to illustrate the ridiculousness and disrespect of phrases like that is to replace "alcohol" with "crack". "I don't do crack anymore" would basically never be responded to with "you know, yo…

"Alcohol is humanity's oldest friend. How could I abandon a friend?" - Yang Wenli The difference is the huge influence alcohol has had on all human cultures throughout history. Yes, it's poison, but it's our poison.

Yep, carry a vice for long enough and it becomes a virtue. It takes a great mind to see this for the folly it is. So can't fault a normal person for not being able to.

Re: Alcohol without the hangover – scientists are finding ways

#218
As someone with severe Asian flush, with an overactive ADH gene (gene that converts of alcohol to acetaldehyde) and 2 defective ALDH2 alleles (gene that breaks down acetaldehyde into harmless byproducts), I wish there is a way to repair these genes using MRNA. I don't feel even the mildest buzz from alcohol but I instantly get a hangover when I drink.

Re: Alcohol without the hangover – scientists are finding ways

#219

I love my IPAs but I have to admit that the UK does social beer right. 3% or even 2.5% ales are the way to go if you want to socially drink. We have a concept of a "session" beer in the US, which is lower ABV but the selection of really good, really low gravity beers is the best in the UK as far as I can tell.

This exists in the US too, it’s called Coors Light (4%). It just tastes like donkey piss.

Re: Alcohol without the hangover – scientists are finding ways

#220
post #165

Earlier quoted context omitted.

Alcohol and caffeine are the only two drugs I can think of (okay, in some circles maybe cannabis too) where the response to "I cut this thing out of my life" is often "why?" or "you know you could still do a little?" One exercise to illustrate the ridiculousness and disrespect of phrases like that is to replace "alcohol" with "crack". "I don't do crack anymore" would basically never be responded to with "you know, yo…

That’s an absurd comparison… crack is no where near as harmful as alcohol

You had me in the first half, not gonna lie... :P
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