Alcohol without the hangover – scientists are finding ways • Hacker News Board

Re: Alcohol without the hangover – scientists are finding ways

#101

Post by spiderice » Sat, Jul 29, 2023, 9:36 PM UTC

anthony_d wrote: post #72

SomeRndName11 wrote: post #57

Earlier quoted context omitted.

Precisely. Most people "enjoy" alcohol because it is socially accepted drug, but for many people so many other substances would be a lot more enjoyable, without collateral damage of alcohol for society. Alcohol is a poor choice for recreational drug for many, for the exceptions those who likes depressants.

Sounds like you didn’t actually read the comment you’re responding to. Any chance you work in politics?

GP's comment is a perfectly acceptable response to GGP's comment. Yours however..

Re: Alcohol without the hangover – scientists are finding ways

#102

Post by boomskats » Sat, Jul 29, 2023, 9:36 PM UTC

I've had a subscription to David Nutt's Sentia Spirits [0] for a few months, which uses an extract from GABA Labs. I enjoy the mild effect and I do think they're onto something, but I have to mix it as it tastes a bit soapy (that's the red, I've yet to try sentia black).

I like the idea that the subscription to Sentia funds the development of Alcarelle (the product mentioned in the article), but the overwhelming reason I subscribe to it is just to support Professor David Nutt[0]. He is a true scientist with true integrity and will be remembered as being on the right side of history. The way he was treated by the UK government at the hands of big booze is an absolute tragedy.

[0]: https://sentiaspirits.com/ [1]: https://en.wikipedia.org/wiki/David_Nutt

Re: Alcohol without the hangover – scientists are finding ways

#103

Post by thehappypm » Sat, Jul 29, 2023, 9:38 PM UTC

andrewstuart wrote: post #85

A hangover is primarily dehydration. Just drink alot of water during your drinking session or before bed.

It’s a lot if things, but also a buildup of acetaldehyde, which is really nasty.

Re: Alcohol without the hangover – scientists are finding ways

#104

Post by thoughtegting » Sat, Jul 29, 2023, 9:38 PM UTC

Some DHM (Dihydromyricetin) before heading out for drinks does the trick for me every time

Re: Alcohol without the hangover – scientists are finding ways

#105

Post by thehappypm » Sat, Jul 29, 2023, 9:38 PM UTC

dgb23 wrote: post #33

1ba9115454 wrote: post #10

I've switched to alcohol free beers. They're a bit sweeter but for me it's fine.

I like drinking a beer or two sometimes during the week. It’s tasty, cool and calming. Alcohol free beer is great for that. However most alcohol free beers don’t taste nice. Takes a bit of shopping around to find a brand that doesn’t taste like Ovomaltine.

Brew Dog is great

Re: Alcohol without the hangover – scientists are finding ways

#106

Post by Frost1x » Sat, Jul 29, 2023, 9:39 PM UTC

jdjdjdjdjd wrote: post #96

I have discovered that for me personally, taking magnesium before, during or shortly after having drinks greatly reduces hangovers. I typically get really strong headaches the day after from 2-3 drinks. If I take a 100mg magnesium supplement it is massively reduced. Alcohol depletes magnesium from your body so I guess it counters that.

I just hydrate and take a multivitamin when I do plan on drinking a bit. And drink lots of water after.

Re: Alcohol without the hangover – scientists are finding ways

#107

Post by mstipetic » Sat, Jul 29, 2023, 9:41 PM UTC

gdprrrr wrote: post #86

quaffapint wrote: post #40

Earlier quoted context omitted.

I have been on the hunt for the past year in the mid-atlantic area of the US looking for Moosehead for example makes a Moosehead Light for the states at 4%, but they also offer Cracked Canoe which is only 3.2% but not sold in the states (available in the Canada, UK and Costa Rica of all places where I tried it).

Here in Germany, it's common to mix beer and sprite 50:50 for a 2,5% drink. It keeps more of the beer taste than you'd think.

It most certainly does not

Re: Alcohol without the hangover – scientists are finding ways

#108

Post by ttul » Sat, Jul 29, 2023, 9:42 PM UTC

PedroBatista wrote: post #53

Oh great, I'm sure this will end as well as the pain pills from Purdue.. There is a sizable minority of people who don't have a "governor" when it comes to drinking, we call them alcoholics. Then there is a big group of people who have some moderation, but part of that "moderation" are the hangovers and by the late 20's they start to hurt much more than consecutive nights of boozing can offer. Let's hope this is yet…

David Nutt is an esteemed scientist. He previously chaired the UK’s Advisory Council on the Misuse of Drugs. He is “ David Nutt is a Fellow of the Royal College of Physicians, Royal College of Psychiatrists and the Academy of Medical Sciences.”

Source: Wikipedia

Re: Alcohol without the hangover – scientists are finding ways

#109

Post by miduil » Sat, Jul 29, 2023, 9:43 PM UTC

I've been three+ years sober, really can recommend. Life is much different now, things that used to be fun aren't anymore - but I'm making strong connections nevertheless.

Re: Alcohol without the hangover – scientists are finding ways

#110

Post by wincy » Sat, Jul 29, 2023, 9:44 PM UTC

Animats wrote: post #95

That's GABA Labs.[1] They've been working on this for years. They have a product, called "Sentia". It's plant-based and "natural", which avoids some regulatory problems. Their better product is an entirely synthetic molecule. It's self-limiting. It's said to produce a pleasant buzz, but more of it won't produce drunkenness. You can buy Sentia. It's insanely expensive.[2] [1] https://gabalabs.com/ [2] https://sentiasp…

It’s less expensive than a good quality whiskey. Honestly I might try some. 50cl == 500ml, so a liter for £54 doesn’t strike me as even “very expensive”, unless I’ve made some major metric maths error.