Still suffering from this myself. I used to train for hours a day nearly every day (BJJ/Calisthenics/KettleBells.) Totally obliterated my exercise capacity after I got Covid twice, first time acute symptoms lasted for 6 weeks, second time was shorter at 3 weeks. Years later and I'm still not the same. It hit hard.
The burden of Long Covid “so large as to be unfathomable”
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Re: The burden of Long Covid “so large as to be unfathomable”
#22There's a popular opinion I've seen on HN that "long Covid" isn't a real phenomenon but it's pretty easy to reject that out of hand. There have been several studies, including a recent quadruple blinded one (where participants, care providers, investigators and outcomes assessors are all blinded to treatment/control groups) that show some interventions have statistically significant benefits to treating it; https://w…
I have all of my running data on Garmin that shows pre and post COVID (at least 3 bouts).
I'm now 90 seconds/km slower, doing the same volume and all other things being equal (except age). My diet hasn't changed, I walk the same distances, climb the same number of stairs, steps per day, weight is the same, etc.
I just cannot get going. Laboured breathing, occasional randomly high heart rate at what would previously have been a LSR (long slow run) pace, where I'd been firmly in zone 3, now randomly hitting zone 5 for bit.
Re: The burden of Long Covid “so large as to be unfathomable”
#23Hasn't there been lots of evidence in the past year suggesting that Covid was created in a lab? If we were to go down this path:
1. Covid created in a lab (not proven, but high enough probability to be considered a reasonable option):
https://oversight.house.gov/release/covid-origins-hearing-wr...
2. If Covid was created in a lab, this de-facto means that Covid has potential as a biological weapon. I don't see how this could be framed any other way. Even if researching novel viruses is in good faith, it doesn't eliminate the reality that they will always have inherit value as biological weapons.
3. Can someone explain to me why there isn't an extremely aggressive campaign to pin down: a. Where it came from b. All parties involved in it's funding and creating c. Passing laws and sanctions to eliminate further continuation of said research. If it was done by China, then they should publicly be held accountable and action should be taken until that is done by all countries.
In this line of assuming Covid was created in a lab, it was one of the most devastating events to the human race in recent history. Many people died and many more people will likely suffer from effects of long covid. It completely warped the global economy.
Is there no attempt at pinning this down and holding people accountable because it can't be proven that it was lab created 100%?
There's a million lesser events every single day that seemingly get more time, money, and energy spent on holding people accountable for infinitely smaller mistakes, accidents, and wrong doings.
Re: The burden of Long Covid “so large as to be unfathomable”
#24Hasn't there been lots of evidence in the past year suggesting that Covid was created in a lab? If we were to go down this path: 1. Covid created in a lab (not proven, but high enough probability to be considered a reasonable option): https://oversight.house.gov/release/covid-origins-hearing-wr... 2. If Covid was created in a lab, this de-facto means that Covid has potential as a biological weapon. I don't see how th…
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Re: The burden of Long Covid “so large as to be unfathomable”
#25There's a popular opinion I've seen on HN that "long Covid" isn't a real phenomenon but it's pretty easy to reject that out of hand. There have been several studies, including a recent quadruple blinded one (where participants, care providers, investigators and outcomes assessors are all blinded to treatment/control groups) that show some interventions have statistically significant benefits to treating it; https://w…
There are some major qualifiers to this study:
1) The ages and BMI:
> The median age was 45 years (IQR 37–54) and median BMI was 29·8 kg/m2
2) The diagnosis of long COVID-19 was done by survey — this has been shown to be an unreliable method of assessing persistent symptoms of disease. This is in part because people will tell you they have symptoms if you give them a cause and ask. The diversity of the claimed presentation of symptoms is an indicator (e.g. > 50 different symptoms by article-in-support [1])
3) The hazard ratio 95% confidence interval extends to 0.99 when treatment is started within three days. This is not a strong result. 1.0 is no effect.
[1] https://www.medicalnewstoday.com/articles/symptom-burden-sur...
Re: The burden of Long Covid “so large as to be unfathomable”
#26Hasn't there been lots of evidence in the past year suggesting that Covid was created in a lab? If we were to go down this path: 1. Covid created in a lab (not proven, but high enough probability to be considered a reasonable option): https://oversight.house.gov/release/covid-origins-hearing-wr... 2. If Covid was created in a lab, this de-facto means that Covid has potential as a biological weapon. I don't see how th…
1. Very well could have been.
2. Virologists have legitimate reasons for wanting to study more dangerous forms of viruses before they appear in the wild.
3. China.
Re: The burden of Long Covid “so large as to be unfathomable”
#27Earlier quoted context omitted.
I think there are a couple of things going on: Long COVID is real, but I bet most people that think they have it don’t. On the other hand, I doubt long COVID is all that novel compared to what happens with other viruses as well. I think there’s some pushback because the media acts like long COVID is some terribly novel and huge thing, when neither are probably true. All that said I’m glad more research is happening o…
Also, millions upon millions of people contracted COVID. Hence a higher number of long-COVID cases. Research into this is a very good thing so. That the media is over selling it, sure they do. Heck, we had almost two straight days of life coverage of lionesse-turned-out-to-be-a-boar in Germany. At the same time there were elections in Spain, a vote on the justice system in Israel, among other things. Those two alone…
Sure. I also have a young daughter in daycare so I've had a cold about every 2 months for the past year and a half. Obviously those haven't been as bad as the two times I had COVID, but we don't really know if that means long term effects are less likely...and people get a lot of colds.
Re: The burden of Long Covid “so large as to be unfathomable”
#28There is a lack of hard scientific evidence definitively proving this. However you may know in your bones that this is real, from lived experience or from people you know. Please keep that in mind when you dismiss other things that lack definitive scientific evidence. We as humans seem to pick and choose which currently unverified things to believe and which to dismiss.
Re: The burden of Long Covid “so large as to be unfathomable”
#29There's a popular opinion I've seen on HN that "long Covid" isn't a real phenomenon but it's pretty easy to reject that out of hand. There have been several studies, including a recent quadruple blinded one (where participants, care providers, investigators and outcomes assessors are all blinded to treatment/control groups) that show some interventions have statistically significant benefits to treating it; https://w…
The intervention is Metformin during Covid onset?
I had the same question. Apparently people who had already been taking Metformin for diabetes were at lower risk of severe Covid [1], which explains why Metformin is being studied.
Looks like the same authors found that Metformin as a treatment after Covid diagnosis did not significantly reduce the the risk of hospitalization or death, even though it does reduce incidence of long Covid.
[1] https://www.covid19treatmentguidelines.nih.gov/therapies/mis...
Re: The burden of Long Covid “so large as to be unfathomable”
#30Earlier quoted context omitted.
Also, millions upon millions of people contracted COVID. Hence a higher number of long-COVID cases. Research into this is a very good thing so. That the media is over selling it, sure they do. Heck, we had almost two straight days of life coverage of lionesse-turned-out-to-be-a-boar in Germany. At the same time there were elections in Spain, a vote on the justice system in Israel, among other things. Those two alone…
Sure. I also have a young daughter in daycare so I've had a cold about every 2 months for the past year and a half. Obviously those haven't been as bad as the two times I had COVID, but we don't really know if that means long term effects are less likely...and people get a lot of colds.
Good news is, as soon as kids grow out of those childcare and pre-school disease magnet super spreader phase, so do you. The cycle seems to repeat with each child so...