Everything here could be summarized under the headline "solve people's annoying, day-to-day problems (in an original manner)". There are some great perspectives here, but I have a (little) problem with the premise of "solve people's annoying problems". I understand that this probably was a business talk to people interested in entrepreneurship, and, certainly this is great advice for people wanting to build a profitable business. But in the end, this is all it is: "how to make lots of money from software? Answer: solve people's annoying problems".
In a society where engineers are arguably playing an increasingly important role, I think this outlook is too limited. This perspective is what I would expect in a CPA convention. If engineers are so smart, powerful and essential, is this what you want to inspire them to do? Have them make cooler gadgets, easier "content consumption experience", better to-do lists to make people more "productive" and, lastly, possibly provide better health so that they would live longer to buy more gadgets and "consume" more "content"?
If engineers are so smart, powerful and essential, why not inspire them to find ways to alleviate poverty and promote justice, education and equality? Well, you say, this is not a job for engineers. Well, if engineers are expected to think of new ways to book sleeping arrangements or sell clothes, their insight can surely be turned to loftier goals. I don't want to be caught saying anything positive about Facebook, but for better or worse, they have changed the way people around the world communicate with each other, compete with each other, and see themselves as part of society. So, yes, engineers are certainly capable of achieving some great feats.
Many lawyers make lots of money. Lots. And probably many of them became lawyers for that purpose. But It's hard for me to imagine - and maybe I'm wrong about this - but it's hard for me to imagine a well known lawyer delivering a keynote speech at a lawyers convention, where his main points are tips for making lots of money. Lawyers may be hypocritical (and they are), but at least many of them separate their business goals from their sources of inspiration. So why should engineers be inspired only by business tips? Is money the main source of inspiration for us? Doctors and lawyers make money, too, but they aspire for - or, at least, are inspired by - more. Even writers, directors and actors aspire for more than making money, or even "delivering content" or providing entertainment. They dream that, perhaps, some of their work might carry some Truth. Give people a new perspective about life, maybe even change people's lives - but not by making them simply more "productive". Peh, productivity - if there ever was a more overrated and servile word.
Anyway, we should aspire to do the same. Fellow engineers, do whatever makes you feel good about yourselves. Do whatever you need to make lots and lots and lots - piles - of money. By all means, solve people's annoying problems; that's a great advice. But don't aspire to that. You should dream about solving humanity's serious problems. You should dream of making this a truly better world - in every respect.