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Tea as Hepatoprotective Agent: A Revisit

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Re: Tea as Hepatoprotective Agent: A Revisit

#21
post #9

Earlier quoted context omitted.

Avoid drinking liquids hotter than 140 f. One interesting "test" - take a sip of the liquid, and it does not seem that hot, put your finger in your mouth with the liquid and your finger might feel too hot.

140 degrees Fahrenheit = 60 degrees Celsius

As another data point, this is generally hotter than most “hot” water taps in your kitchen or bathroom.

Re: Tea as Hepatoprotective Agent: A Revisit

#22

Meta: I'd not realised that Sci-Hub was a permitted site on HN. It appears that it has been since at least 2019 looking at the site submission history link. I'm not in the least displeased to learn this.

Just curious, why did you think it wouldn’t be?

Re: Tea as Hepatoprotective Agent: A Revisit

#25

Meta: I'd not realised that Sci-Hub was a permitted site on HN. It appears that it has been since at least 2019 looking at the site submission history link. I'm not in the least displeased to learn this.

If this is the meta-thread ... this presentation is horrible for mobile and defeats HN's forewarning about PDFs.

Re: Tea as Hepatoprotective Agent: A Revisit

#26
post #9

Earlier quoted context omitted.

Avoid drinking liquids hotter than 140 f. One interesting "test" - take a sip of the liquid, and it does not seem that hot, put your finger in your mouth with the liquid and your finger might feel too hot.

140 degrees Fahrenheit = 60 degrees Celsius

140 degrees Fahrenheit = 344 kelvin

Re: Tea as Hepatoprotective Agent: A Revisit

#27
post #6
post #3

I've been a dedicated tea drinker since my teens, so this is great news. OTOH what I worry about is oesophageal cancer. Not sure of the prevalence.

Don't know any stats from the top of my head, but I recall that oesophageal cancer is caused by drinking _hot_ tea, not by drinking tea per sé.

> drinking hot tea, not by drinking tea per se.

It is unclear to me that there is any way to drink tea than other than piping hot.

I have heard horror stories that suggest people have attempted to drink cold tea but I figure such tales are merely intended to provoke disgust.

Re: Tea as Hepatoprotective Agent: A Revisit

#29

Earlier quoted context omitted.

Hey doc. Well, I had consistently low WBC counts (leukopenia), skin infections, sinus infections, lung infections (and nodules), as well as recurrent fungal infections. Doctors offered no explanation. In 2014 I had my genome run on 23andMe and through digging and getting a second genome run I confirmed that I was homozygous for rs1049564 (and other SNPs) in my PNP gene. I was finally able to push for a PNP activity t…

Wow. I applaud this effort. Been working on studying pharmacogenetics / pharmacogenomics / toxicogenomics focused on phenols such as catechins in tea. (Activity 'C' of https://docs.google.com/document/d/11f2bzMRbAgCJyoaEmxXKVytl... ) Would love to understand how you researched this, as locating relevant research literature has been challenging. (updating my user page with contact)

Hey Rick, it took a lot of time and a lot of emails to people researching the topic. But the key was the doctor's constantly diagnosing me and then diagnosing me with Lupus. Finding the link with Lupus and PNP SNPs was the key. The Lupus diagnosis was always back and forth because apparently PNP deficiency lowers immunoglobulin levels as well and that is the test that gets you in the door to the rheum only when it is high.

Many other phenol's and polyphenols seem to give me issues as well.

Also, you might take a look at the interaction between riboflavin and catechins. There is something going on there I do not quite understand:

https://www.mdpi.com/1422-0067/9/10/1908

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837740/

Re: Tea as Hepatoprotective Agent: A Revisit

#30
post #27
post #6

Earlier quoted context omitted.

Don't know any stats from the top of my head, but I recall that oesophageal cancer is caused by drinking _hot_ tea, not by drinking tea per sé.

> drinking hot tea, not by drinking tea per se. It is unclear to me that there is any way to drink tea than other than piping hot. I have heard horror stories that suggest people have attempted to drink cold tea but I figure such tales are merely intended to provoke disgust.

Cold tea does indeed provoke disgust. Iced tea, on the other hand, is quite its own art form.
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