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Benzene Exposure Alters Endocrine Activity

ncbi.nlm.nih.gov

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Re: Benzene Exposure Alters Endocrine Activity

#41

Post by hammock »

refurb wrote: post #34
hammock wrote: post #3

Benzene is everywhere, particularly in trace amounts in otherwise harmless products. Benzene is a building block for the production of many chemicals, including plastics, synthetic fibers, rubber, resins, dyes and pharmaceuticals, and residual amounts may remain in the final products. Benzene is used as a solvent and cleaning agent in printing, paint manufacturing, electronics, etc. Benzene contributes to the overall…

The dose makes the poison. Currently chemical analysis techniques can detect compounds down to picograms/L. That's billionth's of grams per liter. So saying "this material has benzene in it", doesn't really tell you anything about the level of exposure or risk. Very few compounds are toxic at that kind of exposure.

The study in question literally says a small dose is about as effective as a massive dose.

Re: Benzene Exposure Alters Endocrine Activity

#43

Post by mrguyorama »

EatingWithForks wrote: post #26
xkcd-sucks wrote: post #8

Earlier quoted context omitted.

If you're into super ~metal~ dystopian weight loss aids that are available today, check out https://en.wikipedia.org/wiki/2,4-Dinitrophenol

Yeah frankly I'd rather fat people stay fat and focus on lifestyle changes to health, fat or not, than eating life threatening explosives to get thin.

I agree with your opinion, but the other way to look at it is that most fat people know they are fat, "want" to do something about it, but just don't because losing weight is really hard, from a human level. Millions of years of evolution are working against you to lose fat stores, because 99.99% of people who have ever done that starved to death.

If sketchy drugs are the only ACTUAL way to get the 3/4ths of the country to lose weight and be healthier, shouldn't we try it?

Though, the end result of that is probably finding out that if you are a "healthy" weight from drugs, but your diet is still mainly mcdonalds and steaks and food made mostly of butter, you probably will have just as many health problems. And there's no exercise drug.

Re: Benzene Exposure Alters Endocrine Activity

#44

Post by angst_ridden »

Back in the day, I worked at a print shop as a press operator for AB-Dick 360CD printing presses.

We'd clean the ink off the rollers between separations with benzene. We didn't have any special ventilation (or even use gloves, for that matter). The first few times you did it, you'd get quite a headrush.

It's 40 years on, now, and I haven't yet experienced any health effects that I can directly link to that exposure. I'm sure I'm dumber than I would have been had I avoided the exposure, although I also grew up in the era of leaded gasoline. Based on what I've read, I'm more likely to experience Parkinson's, anemia, and various cancers in the future.

Re: Benzene Exposure Alters Endocrine Activity

#45

Post by mistrial9 »

nimos wrote: post #38
refurb wrote: post #34

Earlier quoted context omitted.

The dose makes the poison. Currently chemical analysis techniques can detect compounds down to picograms/L. That's billionth's of grams per liter. So saying "this material has benzene in it", doesn't really tell you anything about the level of exposure or risk. Very few compounds are toxic at that kind of exposure.

A lot of chemicals seem to have effects on the endocrine system. I wonder if there is potentially an issue with them in aggregate. Such that the dose of any single chemical isn't problematic but all of them together with similar effects causes a problem.

you are right -- keyword search "body burden" or "forever chemicals"

Re: Benzene Exposure Alters Endocrine Activity

#47

Post by karmakaze »

All I recall besides being one of many carcinogens is that it's in cigarette smoke. From a Dutch health page. [https://www.rivm.nl/en/tobacco/harmful-substances-in-tobacco...]

> For smokers, tobacco smoke is the most important source of exposure to benzene. It is released in the smoke when tobacco is burned. Non-smokers are also exposed through tobacco smoke when they inhale smoke passively. A typical smoker inhales an average of ten times more benzene per day than a non-smoker.

Re: Benzene Exposure Alters Endocrine Activity

#49

Post by refurb »

hammock wrote: post #41
refurb wrote: post #34

Earlier quoted context omitted.

The dose makes the poison. Currently chemical analysis techniques can detect compounds down to picograms/L. That's billionth's of grams per liter. So saying "this material has benzene in it", doesn't really tell you anything about the level of exposure or risk. Very few compounds are toxic at that kind of exposure.

The study in question literally says a small dose is about as effective as a massive dose.

That's because it's a terribly designed study. Their lowest dose shows maximum effect, they should have also tested 0.1 mg/kg.

And 1mg/kg of body weight is way more than any person would be exposed to unless you like drinking gasoline.

Re: Benzene Exposure Alters Endocrine Activity

#50

Post by zinclozenge »

mikeodds wrote: post #29
zinclozenge wrote: post #17

Earlier quoted context omitted.

I took a standard DNP fat loss dose, the effects (weight loss and others) are vastly overstated. You'd have to take well in excess of any recommended dose to get to the point where the waste heat production would become dangerous. You're more likely to develop a cataract as a deleterious effect. I'd wager most of my weight loss came from the fact that I just wasn't eating because I felt awful.

were you training at the same time? any noticeable effects if so?

I tried, but DNP basically gave me a perpetual fever (aka pyrexia) so I didn't train. I assume it would have had a pretty noticeable effect though.
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