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Modafinil and Startups

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Re: Modafinil and Startups

#41
post #15

What I found with more experimentation of days both with and without Modafinil was that actually, I was just as productive if I was well rested, healthy, well fed with healthy foods and working on something I cared about. This, I think, is the most interesting part of the entire piece. He talks at length about the benefits of Modafinil: On the good side, those tasks which I did line up got done, and with great energy…

That is my own main takeaway... Which is why I don't take Modafinil anymore.

Did you post this once before? The entire article and especially the conclusion/takeaway sounds so very familiar! (but the publication date is today)

Re: Modafinil and Startups

#42
post #22

Modafinil is also compared to amphetamines (which are often used either for recreation or to treat ADHD), since its effect is somewhat similar. Generally, the comparison states that amphetamines are bad for you and that Modafinil is not as bad because it "works differently", but there is probably more overlap than the proponents of Modafinil would like you to think. There is one massively huge difference between amph…

Addiction is not just in the mind

Addiction, in rats at least, appears to be more in the environment than the body. Rat Park[0] is a fascinating experiment demonstrating this.

[0] http://en.wikipedia.org/wiki/Rat_Park

Re: Modafinil and Startups

#43
I have taken 200mg of Modafinil daily for more than 5 years.

Before it, I could go to sleep just about anywhere and just about any time. I could easily sleep for 12 to 14 hours a day if I let myself. When I had a work commute of about an hour and a half, I would have to pull over, sometimes four or five times, during the afternoon drive home to take cat naps because I couldn't keep my eyes open. It didn't matter how much or how little coffee I drank, it didn't matter how much I slept the day before, and it didn't matter whether I was eating my typical diet which was fairly healthy, or if I had unusual amounts of junk food that week.

Caffeine doesn't work "normally" for me. I like the taste of coffee, I usually have one cup a day that I sip throughout the morning. However, I don't have a Folgers moment. I am not groggy until I get my first cup. If I drink a soda or coffee or even have a shot of espresso in the afternoon, I don't get a sudden boost of energy. I don't even get the boost of energy from energy drinks. When I drink a lot caffeine or other energy drinks in a short period of time, I find that they will give me a mild case of the jitters, but even then, they don't counteract my actual drowsiness. Hence, I've never gone higher than my typical cup of coffee in the morning and frequently a soda in the afternoon. More than that has almost all down-sides and no up-sides for me.

I took a sleep study, and I was not diagnosed with narcolepsy because that diagnosis is very specific. You must immediately fall into REM sleep. I was diagnosed with a "we have no idea what you have" condition of excessive daytime drowsiness and received a prescription for Provigil. Originally, it was a 100mg dose, but when that was not effective, it went up to 200mg.

It is a bit of a wonder drug for me, but certainly not in the terms that it was described in this article. It doesn't make me hyper focused or give me unusually sharp focus, it just removes the incapacitating drowsiness I suffered in the afternoon. I've actually found that music is more distracting to me during work hours since I started taking it. While I still enjoy listening to various types of music for recreation, I don't play music while working anymore.

I would definitely say it is not addicting in the manner that coffee is. On vacations and at times I didn't have my prescription with me, I've gone weeks without taking it. There are no withdrawal symptoms, other than the fact that I would be excessively drowsy again, especially in the afternoon. If I stop drinking caffeine, I will suffer migraines for about two weeks.

I will agree with the part about broad focus vs narrow focus. I can think better about large system design late in the evening. When I am working on an architecture problem during the afternoon, I find myself frequently rat-holing. I'll focus on one specific part and just keep going back to it over and over rather than spending enough time at the higher level.

Re: Modafinil and Startups

#46

What I found with more experimentation of days both with and without Modafinil was that actually, I was just as productive if I was well rested, healthy, well fed with healthy foods and working on something I cared about. This, I think, is the most interesting part of the entire piece. He talks at length about the benefits of Modafinil: On the good side, those tasks which I did line up got done, and with great energy…

I was just as productive if I was well rested, healthy, well fed with healthy foods and working on something I cared about.

Those are four conditions that are difficult to fulfill 24/7. I'd go so far as to say that it's difficult to have a normal social life and always be well-rested and fueled with healthy foods. Case in point: I have a dance class on Wednesday nights that breaks up after ten o'clock. No way I'm sleeping until 1am or 2am on those nights. But I exercise in the mornings, so I can't stay up until 1am or 2am every night. My life is an engineering exercise, and like any engineering exercise, there are a lot of compromises. I'm curious about using Modafinil judiciously to make up the gap once in a while, possibly at the once-per-few-months frequency he says would be okay. It's incredible what our body will do -- virtually anybody can run a marathon, for example -- but it takes a lot of orchestration to convince our body to release its miserly grip on our resources and do the job we'd like it to do.

Re: Modafinil and Startups

#47

I have taken 200mg of Modafinil daily for more than 5 years. Before it, I could go to sleep just about anywhere and just about any time. I could easily sleep for 12 to 14 hours a day if I let myself. When I had a work commute of about an hour and a half, I would have to pull over, sometimes four or five times, during the afternoon drive home to take cat naps because I couldn't keep my eyes open. It didn't matter how…

Clearly you have a medical condition you're treating with modafinil which will make the way you respond a bit different than a "normal" person. It's interesting to hear the differences in response.

Re: Modafinil and Startups

#48
I would agree that occasional use isn't a good idea. I've done that and it really is more trouble than it's worth. That said I still do it. If I have a day where I'm extra lazy I'll take a Nuvigil (Armodafinil, which is the active isomer of Modafinil) and be productive but with some side effects which include

Headaches

Nervousness

Some inability to focus between tasks

I've also found dosage has a sweet spot. I wouldn't take less than 150mg of Nuvigil as lower dosages make me strangely more nervous.

Re: Modafinil and Startups

#49

What I found with more experimentation of days both with and without Modafinil was that actually, I was just as productive if I was well rested, healthy, well fed with healthy foods and working on something I cared about. This, I think, is the most interesting part of the entire piece. He talks at length about the benefits of Modafinil: On the good side, those tasks which I did line up got done, and with great energy…

The conditions aren't mutually exclusive. You can be "healthy, well fed with healthy foods", exercise, and still use modafinil to counteract lack of sleep. I completely agree that eating properly and exercising (or not) will have a huge impact on productivity but they do not make up for sleep.

Re: Modafinil and Startups

#50

What I found with more experimentation of days both with and without Modafinil was that actually, I was just as productive if I was well rested, healthy, well fed with healthy foods and working on something I cared about. This, I think, is the most interesting part of the entire piece. He talks at length about the benefits of Modafinil: On the good side, those tasks which I did line up got done, and with great energy…

Taking a pill, however, is much easier than keeping a proper diet and sleep schedule and working only on what you like...

And no matter how awesome your project, there will be times that you must push through the muck.
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