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Psychedelic scientist sends brains back to childhood

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Re: Psychedelic scientist sends brains back to childhood

#71
post #65
post #57

Earlier quoted context omitted.

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> Very few conservatives in 2023 are riled up by homosexuality. This is absolutely not the case at the populist grassroots level. There are regular panics and outpourings of hatred for pride events, books mentioning homosexuality are outright banned in schools, gay teachers are targeted for harassment and fired. My state just passed a law banning drag shows, which have been a part of gay culture for decades. Genuine…

I don’t live in a red state but I was raised in the most socially conservative area of Canada and I do have a number of religious and evangelical friends though I was raised atheist. Granted I do now live in the gayest neighbourhood in Canada.

The level of homophobia I witnessed and experienced in the nineties was on another order than what exists today, there is absolutely no comparison (I’m not gay but was routinely called a fag even by strangers because I was a skinny kid with long hair and had gay friends). In the nineties I would read conservative magazines that had ads in them pushing conspiracy theories about how the NAZI leadership were all gay. DOMA was a huge issue that ate up a lot of national politics in 2004, even California voted against gay marriage in a referendum. In 2012 Obama was still compelled to campaign in defense of DOMA and was openly supportive of marriage only between men and women (though interestingly the earliest activists for marriage equality came from the centre-right (Sullivan and Rauchman)).

Now the nuttiest MAGA republicans all love George Santos, who was a literally drag queening in Brazil and Peter Thiel who got a massive cheer when he keynoted the 2016 convention and said “I am proud to be gay. I am proud to be a Republican. But most of all I am proud to be an American.” Unthinkable even 4 years prior. One poll of gay men in 2020 shows 46% support for Trump. [0] On the more traditional Republican side of things (Dispatch conservatives and Reason Libertarians) it’s hard to find many living authors who are more valourized than Deirdre McClosky who has been trans for 30 years.

It’s possible that homophobia has increased a bit in the last few years amongst social conservatives, but it still isn’t close to anything like it was even a decade ago. So if it has increased, and if young people are reverting to viewing sex as a binary according to a recent Pew poll [1] the question is why. Partly it’s the weird corporate and state monomania around the topic. But more than that, as I stated above, it seems to me to be mixed with blowback to gender ideology which has been conflated with gay rights, even though it is a very different and contradictory thing with a whole separate host of questions around medical ethics and educating children that many don’t find to be consistent with the positive message that universalized gay rights - you’re fine the way you were born and you don’t need to change anything to be accepted.

[0] https://www.nbcnews.com/feature/nbc-out/trump-applauds-poll-...

[1] Most favor protecting trans people from discrimination, even as growing share say gender is determined by sex at birth - https://www.pewresearch.org/social-trends/2022/06/28/america...

Re: Psychedelic scientist sends brains back to childhood

#72

Earlier quoted context omitted.

Can you expand on this? I find it hard to understand what similarities you see to what children today are being “exposed” to and Charles Manson drugging people with LSD and convincing them to kill other people.

I think they're suggesting that young children--in their critical (mental) periods--can somehow turn gay or transgendered due to exposure/normalisation of gay and trans people. Except there's no science to back this up. All the scientific articles I've ever seen on the topic of gender and sexuality seem to indicate that the critical period for those attributes develop in the womb and not during childhood. The most li…

> I think they're suggesting that young children--in their critical (mental) periods--can somehow turn gay or transgendered due to exposure/normalisation of gay and trans people.

My personal belief is that the exposure/normalization is good because it helps people discover themselves. And I read that comment somewhat differently: exposure to these concepts might be controversial because parents have such different impressions of what is "right", so they might end up accidentally brainwashing their child. It already happens a lot, and people obviously don't want more of it.

Re: Psychedelic scientist sends brains back to childhood

#73

Interesting factoid in the preamble: the biochemical basis of the addictive nature of social media? > "Oxytocin and serotonin, she found, work together in a brain region called the nucleus accumbens to produce the good feelings that come from social interaction." LSD and similar drugs can definitely improve one's 3D-visualization capabilities, but I think this requires putting in a fair amount of work on the concepts…

> "Oxytocin and serotonin, she found, work together in a brain region called the nucleus accumbens to produce the good feelings that come from social interaction."

Well, this supports my hypothesis on why talking to people was a really good coping mechanism for ADHD. As far as I can tell, oxytocin isn't dampened(?) like dopamine presumably is.

(I say presumably because of the specific symptoms I had and also the specific ways in which stimulants help with them, but I've never had my brain dissected or anything to confirm, seeing as I'm still alive and all.)

Re: Psychedelic scientist sends brains back to childhood

#75
post #57

Earlier quoted context omitted.

I think you're right. On one side, you see adults who believe that sexuality and cross-gender identification are immutable, or at least practically immutable. Their goal is to expose e.g. heterosexual kids to the idea that some of their peers will be different from them so that they aren't shocked and scandalized by it later, then lash out unfairly as a result of prejudice against the unknown. On the other side, you…

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The LGB alliance are a weird one to mention, they have basically no grassroots members at all -- they popped up out of nowhere a few years ago, the average LGBT person in the UK doesn't know they exist at all.

They perform no advocacy to speak of within the UK except for pursuing attack lines against trans people. They're based at 55 Tufton Street which just so happens to also be where a bunch of very curiously linked conservative think tanks promoting anti-climate change, anti-immigrant populist politics are centered. They're mysteriously mixed closely with American groups like the heritage foundation. Oddly they started getting cited a bunch by openly transphobic BBC journalists, ostensibly for "balance" when discussing the rights of trans people.

I cannot think of a more obvious example for astroturfing than this group. They have literally zero presence in real people's lives the way you'd expect a charity to, they instead pop up wherever anti-trans rhetoric appears online and in papers, providing a denigrating voice to whoever needs it. They provide no services and give no advice -- here's to hoping they lose their charitable status when the Good Law Project's appeal concludes later this year.

Re: Psychedelic scientist sends brains back to childhood

#76

Earlier quoted context omitted.

Can you expand on this? I find it hard to understand what similarities you see to what children today are being “exposed” to and Charles Manson drugging people with LSD and convincing them to kill other people.

I think they're suggesting that young children--in their critical (mental) periods--can somehow turn gay or transgendered due to exposure/normalisation of gay and trans people. Except there's no science to back this up. All the scientific articles I've ever seen on the topic of gender and sexuality seem to indicate that the critical period for those attributes develop in the womb and not during childhood. The most li…

Sexuality is so culturally determined though. I mean it seems rather obvious you will get more experimentation in sexuality without rigid taboos and religious dogma against experimentation.

We pretend like people don't get turned on by their own hand.

Re: Psychedelic scientist sends brains back to childhood

#77
post #47

Earlier quoted context omitted.

Nah. That would be because one political party sustains itself by keeping it's voter base on a treadmill of fear and outrage, is moving strongly towards authoritarianism, and has a large contingent specifically intent on implementing a flavor of religious fascism called Dominionism (cf. "Seven Mountians Mandate"). These latest "topics in the culture wars" are simply that, the latest usable tools that can be used, alo…

"That would be because one political party sustains itself by keeping it's voter base on a treadmill of fear and outrage," Pot calling the kettle black right here

Right.

Fear of a concerted effort to remove rights to everything from free speech, to reading books, to healthcare, to voting and actively destroying the independence of institutions whose independence is required to maintain democracy is exactly the same as fabricated fear ginned up with lies about minorities such as trans, Jews, and blacks.

If you want to play at the pot-kettle game level, I'd point out that your statement is mere spouting of the standard line of the deluded herd. Not suitable for this forum. Please bring some facts next time.

Re: Psychedelic scientist sends brains back to childhood

#79
post #53

Earlier quoted context omitted.

Beginning of my MD PhD program a guy who was big in that field and tried small scale trials gave a whole schpill about how big pharma was unfairly blocking this. Then I spent over an hour talking to him about it. This field has a huge challenge finding a consistent and reproducible outcome to aim for. When I pressed the guy he was pretty clear that there were participants in these studies that has pretty bad outcomes…

> When I pressed the guy he was pretty clear that there were participants in these studies that has pretty bad outcomes and would have been in bad shape if there wasnt a medical team on hand Are you aware of source-able examples of this? I’ve been paying attention to the field for awhile, and I was under the impression that between pre-screening (people at risk for psychosis and a few other specific psychiatric issue…

TBH Id have to dig into my notes more than I care to now, but recall looking up his and his coauthors research at the time and the verbage was very similar to what you described. But that's kind of the point. Requiring a specific controlled setting with a medical team and someone to guide the individual through throughout the process is a lot of work to require for "good" outcomes.

The only time you can expect a drug will get approval without large reproduction of quantifiable outcomes is treating some aspect of a rare disease.

Re: Psychedelic scientist sends brains back to childhood

#80
post #53

Earlier quoted context omitted.

> When I pressed the guy he was pretty clear that there were participants in these studies that has pretty bad outcomes and would have been in bad shape if there wasnt a medical team on hand Are you aware of source-able examples of this? I’ve been paying attention to the field for awhile, and I was under the impression that between pre-screening (people at risk for psychosis and a few other specific psychiatric issue…

TBH Id have to dig into my notes more than I care to now, but recall looking up his and his coauthors research at the time and the verbage was very similar to what you described. But that's kind of the point. Requiring a specific controlled setting with a medical team and someone to guide the individual through throughout the process is a lot of work to require for "good" outcomes. The only time you can expect a drug…

> Requiring a specific controlled setting with a medical team and someone to guide the individual through throughout the process is a lot of work to require for "good" outcomes.

Honestly this sounds like an incredibly small amount of work when considering the work involved in traditional therapy and/or psychiatric treatment, which plays out on a timescale of years if not an entire lifetime for some, and collectively requires a “medical team” numerous times.

And when the outcomes involve radical (lasting) improvement to everyday experience for individuals with treatment-resistant depression, I strongly question the urge to trivialize this with scare quotes about “good” experiences and their apparent cost.

> The only time you can expect a drug will get approval without large reproduction of quantifiable outcomes is treating some aspect of a rare disease

The good news is that there’s been quite a bit of progress, and growing interest in medical circles due to the positive outcomes. I’d strongly recommend looking at the latest studies/results; it sounds like you may be operating on some very dated information.

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