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Serotonin booster leads to increased functional brain connectivity

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51–60 of 293 posts

Re: Serotonin booster leads to increased functional brain connectivity

#52

Earlier quoted context omitted.

The main reason it's not too exciting to me is much simpler. They tested it for 6 days. You can do all sorts of wonderful stuff with a drug for a few days. But for most drugs, the effects simply cease if you keep taking it due to tolerance. And there doesn't seem to be a huge amount of leeway to up the dose either because it's a laxative.

I think this is a overly pessimistic take. It would be nice to see a longer term study. And no people shouldn't be buying this in IndiaMart but critical analysis of studies isn't just about being as pessimistic as possible. It's overly pessimistic as it's not constructive. Instead of asking for longer term studies you declare the effect probably won't last. There are loads of criticisms one could make of the study an…

It’s the case with many nootropics, for many people, so I don’t think this is especially pessimistic.

Re: Serotonin booster leads to increased functional brain connectivity

#54
post #33

Something in our industrial processes must be screwing with people's serotonin levels because Psychedelics and other serotenergic drugs are becoming the defacto treatment method for a whole host of ailments. I personally suffer from IBS, migraines, sleeping problems, and mood swings, if I haven't taken a dose of psychedelics in the last 6 months. Now, getting regular exercise, eating well, staying hydrated, sleeping…

100-150 years ago we were using heroin, cocaine, and morphine for such things as cough syrups, hay fever, cola. Ancient Romans used cannabis and opium for insomnia and earaches. Wild animals get drunk on rotten fruit, cats stone themselves on catnip. So you're not wrong to wonder why people take stuff, but none of that's new .

Just because it's one of my favourites, we even have evidence of it in rock art:

https://www.atlasobscura.com/articles/psychedelic-mushroom-a...

Re: Serotonin booster leads to increased functional brain connectivity

#55

Earlier quoted context omitted.

yes, actually all the improvements mentioned in the article reminiscence me of positive effects of psychedelics. They happen to act on serotonin receptors, too.

Do you mind if I ask you - how have you had an account here since 7/5/12 and you only have 1 karma point? I'm flattered that you're responding to my post.

Not the parent, but one reason is if they never comment/post. How else would they get karma?

Re: Serotonin booster leads to increased functional brain connectivity

#56

I remember during my PhD, already 5 or more years ago, the term "functional connectivity" was frowned upon by the computational neuroscience community and the concept was considered out of date.

Perhaps "computational neuroscience" is not the be all end all of neuroscience though...

(not that you said so, but someone might think that if comp. neurosc. dismisses it, then it's necessarily bogus)

Re: Serotonin booster leads to increased functional brain connectivity

#57

Something in our industrial processes must be screwing with people's serotonin levels because Psychedelics and other serotenergic drugs are becoming the defacto treatment method for a whole host of ailments. I personally suffer from IBS, migraines, sleeping problems, and mood swings, if I haven't taken a dose of psychedelics in the last 6 months. Now, getting regular exercise, eating well, staying hydrated, sleeping…

>Now, getting regular exercise, eating well, staying hydrated, sleeping 8 hours a night, spending time with friends, sexual and emotional fulfillment, and performing fulfilling labor, that will get you 80% or even 100% towards fixing most, if not all your problems.

Each of those is quite harder to achieve these days (due to work pressure, everpresent and ever-promoted processed foods, screen time, a borked dating scene, the abundance of crap jobs, and so on), even more so all of them combined...

Re: Serotonin booster leads to increased functional brain connectivity

#58
I wish we stopped treating serotonin as a button that automatically improves mood. It is bullshit. Let's recognize the complexity of neural signaling. Whenever people call serotonin the happiness hormone I want to throw up. Such people would probably never believe that if you inject serotonin, the result is extreme pain at the injection site.

Re: Serotonin booster leads to increased functional brain connectivity

#59
post #34

Could this potentially help schizophrenia, emotional regulation, impulsivity, reward processing, ADHD etc because of an improvement in functional connectivity?

Anecdotally, I've used it on and off for about 10 years now and personally notice a strong correlation with impulse control. I have an OCD diagnosis and the only two things that have worked to manage symptoms are consistent journaling, exercise, yoga, meditation and therapy (all together), and 5-HTP.

Re: Serotonin booster leads to increased functional brain connectivity

#60
post #55

Earlier quoted context omitted.

Do you mind if I ask you - how have you had an account here since 7/5/12 and you only have 1 karma point? I'm flattered that you're responding to my post.

Not the parent, but one reason is if they never comment/post. How else would they get karma?

Which I think is the point of person you're responding to. His comment has someone get out of one's ten year silence. Pretty flattering indeed.

Ironically, I would not have understood that if not for your comment.

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