The "Hello World" example is a really good example of why React, Vue, etc are better than something more minimal like this library if you're optimizing for speed. The page will show nothing until the script runs, which requires downloading the VanJS lib and the script itself. You could inline them into the page, but that gets seriously messy at scale. A modern React app that's using some serverside rendering for the…
If you know what you are doing you can achieve full state restoration of a large SPA before CSS paints to the screen. In my personal app I am able to complete state restoration within the first 80ms of page load on old hardware. Vue and React are not capable of providing this.