Live data from Hacker News

Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

161–170 of 504 posts

Re: Ozempic drug supresses desire to smoke, drink and more?

#161
post #61

What happens when you reach your target weight with drugs like this? After having learned potentionally nothing about nutrition, exercise, and self-control, are you stuck on these meds for life out of fear of binge-eating back to your original weight? FWIW I'm on a hundred-pound roller coaster ride from 300lbs to 200lbs; currently ~215. I've learned a lot about discipline and sustainable habits along the way.

[deleted]

Re: Ozempic drug supresses desire to smoke, drink and more?

#162

Yes. On a compounded semaglutide. I can finally control my hunger and a nice unexpected effect has been losing a desire to drink large quantities of alcohol. I don’t drink during the week anyway, but it seems to be the volume that turns me off to drinking. Thus a few cocktails are all I can tolerate. For context, Im 30, male, would be defined as a binge drinker on weekends. Oh, and I’ve given up nicotine entirely. I…

I'd hazard a guess that nicotine is one of the two or three most addictive substances known to humanity. Opiates/heroin is probably worse, world of warcraft is probably third :-) The drug probably helped.

[deleted]

Re: Ozempic drug supresses desire to smoke, drink and more?

#163

Yes. On a compounded semaglutide. I can finally control my hunger and a nice unexpected effect has been losing a desire to drink large quantities of alcohol. I don’t drink during the week anyway, but it seems to be the volume that turns me off to drinking. Thus a few cocktails are all I can tolerate. For context, Im 30, male, would be defined as a binge drinker on weekends. Oh, and I’ve given up nicotine entirely. I…

I'd hazard a guess that nicotine is one of the two or three most addictive substances known to humanity. Opiates/heroin is probably worse, world of warcraft is probably third :-) The drug probably helped.

Don’t forget caffeine!

Re: Ozempic drug supresses desire to smoke, drink and more?

#164
post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

Yeah, that's definitely always been my challenge with weight loss. I have zero problem with self control -- I can easily cut calories in half or less (e.g. 1000-1200 cal/day), but it's simply that my body suffers immensely. I lose all energy, can't concentrate on anything, and my immune system weakens so I start getting colds constantly. I'm sure I'd easily lose weight with Ozempic but I'd still be suffering health i…

That reaction may have to do with too much cutting, as another commenter alluded to, but it may also have to do with the types of nutrients you are missing when cutting.

Re: Ozempic drug supresses desire to smoke, drink and more?

#165
post #57
post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

Your relative’s sad story reminds me of a short story I read a few years ago about a miracle pill that leaves about 90% of its takers perfectly slim and able to stay that way eating anything, after a few truly disgusting initial days of elimination, but kills the other 10% gruesomely. Because it’s so wonderfully effective for the majority, there ends up being a ton of social and economic pressure for anyone even slig…

Thank you, thank you so much for sharing that. It's been a while since the last time my mind was blown away that much.

Re: Ozempic drug supresses desire to smoke, drink and more?

#166
post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

I started Wegovy about 5 months ago. The first couple months you feel sick but after it passes your appetite is extremely curbed (in a good way). Would highly recommend people to try it as it's made me healthier in pretty much every way.

Bold move to name their pharmaceutical like a Chinese Amazon “brand” of AliExpress-sourced electronics.

Re: Ozempic drug supresses desire to smoke, drink and more?

#167

Earlier quoted context omitted.

I'd hazard a guess that nicotine is one of the two or three most addictive substances known to humanity. Opiates/heroin is probably worse, world of warcraft is probably third :-) The drug probably helped.

Don’t forget caffeine!

I like caffeine, unfortunately even small amounts tend to make me irritable and sick at the end of the day. Wasn’t always like that

Re: Ozempic drug supresses desire to smoke, drink and more?

#168

Yes. On a compounded semaglutide. I can finally control my hunger and a nice unexpected effect has been losing a desire to drink large quantities of alcohol. I don’t drink during the week anyway, but it seems to be the volume that turns me off to drinking. Thus a few cocktails are all I can tolerate. For context, Im 30, male, would be defined as a binge drinker on weekends. Oh, and I’ve given up nicotine entirely. I…

I'd hazard a guess that nicotine is one of the two or three most addictive substances known to humanity. Opiates/heroin is probably worse, world of warcraft is probably third :-) The drug probably helped.

Society makes it hard as well. It’s unacceptable to be falling asleep high on opiates. Hitting a vape on a video call with coworkers is considerably more acceptable.

Re: Ozempic drug supresses desire to smoke, drink and more?

#169

Earlier quoted context omitted.

>>due to the fact that eating now makes her sick. Reminds me of the first FDA approved weight loss drug, Alli, that basically just gastrointestinally punishes you if you eat more than a few grams of fat. https://en.wikipedia.org/wiki/Orlistat#Side_effects

> The manual for Alli makes it clear that orlistat treatment involves aversion therapy, encouraging the user to associate eating fat with unpleasant treatment effects. Christ. This is like Crohn's disease in pill form. One too many teaspoons of olive oil and you're in for an unpleasant evening...

I don't have a colon (but I do still have a functioning anus). The effects from orlistat are very similar to what I experience 24/7. If you're under 30 or so, eventually your sphincter gets much, much stronger and the excess oil stops affecting you nearly as much. You can hold it in indefinitely until your normal "need to go" timing. This takes about a year or so to train, and you'll have quite a few accidents in the meantime.

I still can't eat too much salmon in one sitting though :-( I don't get diarrhea but I do get stuck on the toilet for ages after.

Re: Ozempic drug supresses desire to smoke, drink and more?

#170
post #151

I’ve been on Mounjaro since August. Down almost 60lbs, and it’s been a life changer. Have I had some gastrointestinal issues, sure, but expected. I feel great and my brain seems to be functioning as well as when I was in my 20’s. Now, when I go to the bar with friends, I end up having maybe 2 beers and although enjoyable, I don’t feel that light switch turning on which encourages me to drink more. Can I force myself…

the most surprising thing to me is how you’re describing normal behavior that I can relate to all my life, but the community of strugglers is so big that this is a whole testimonial people feel comfortable and exalted to share

like thats not something I’m deriding its just news to me

makes me wonder what this drug actually does, flush gut bacteria? just the right ones?

Post reply on HN