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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

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Re: Ozempic drug supresses desire to smoke, drink and more?

#101

Post by pixl97 »

NickC25 wrote: post #82
amanaplanacanal wrote: post #59

Earlier quoted context omitted.

Unfortunately, suggesting that people eat less and exercise more doesn’t seem to actually work that well. We’ve been trying that for decades and the obesity epidemic just keeps getting worse.

Probably because people aren't acting on it, or sticking with it long enough to actually see results. Especially in today's world when they can just take a pill and loose 10-15 pounds, nobody wants to do something they probably don't like doing (consistent exercise or healthy eating) as part of a short-term or long-term process. A lot of people, especially those in food deserts or without access to adequate nutrition…

Weight has been increasing for nearly 40 years now in the US among all groups. Trying to point this out as any kind of individual failure just has not, and is not going to work. It's tantamount to telling someone to stop smoking in 1950. Yes, some people did manage to, but the vast majority stopped smoking when their lungs no longer supported them living.

When pretty much everywhere you go is plastered in signs saying "EAT THIS YUMMY UNHEALTHY BULLSHIT" and said bullshit is cheap and highly available don't be surprised when we have society wide problems. Add to that our work practices commonly have us hold down a computer for 8 hours a day, it should be no surprise we are where we are.

Re: Ozempic drug supresses desire to smoke, drink and more?

#102

Post by renewiltord »

lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

[flagged]

Re: Ozempic drug supresses desire to smoke, drink and more?

#103

Post by pixl97 »

opportune wrote: post #79
rektide wrote: post #16

Earlier quoted context omitted.

I'm not that afraid of swallowing random chemicals but self injecting is a bit hardcore for me.

Steroid users do it all the time and I haven’t heard of steroid users dealing with infections much.

I'm sure its because most people aren't going to talk about illegal drug use and when it goes wrong.

Re: Ozempic drug supresses desire to smoke, drink and more?

#104

Post by User23 »

ortusdux wrote: post #44
lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

>>due to the fact that eating now makes her sick. Reminds me of the first FDA approved weight loss drug, Alli, that basically just gastrointestinally punishes you if you eat more than a few grams of fat. https://en.wikipedia.org/wiki/Orlistat#Side_effects

My favorite fat loss drug along these lines is dinitrophenol. It is the true miracle fat burning drug. It interferes with cellular metabolism in such a way that the body just nonstop oxidizes fat. Fat mass loss in the order of a pound a day or more is entirely possible and some bodybuilders use it to get to a ludicrously low bodyfat percentage. Unfortunately oxidizing that much fat generates a lot of heat, so much that an overdose can be lethal because your body literally roasts itself to death and titration is extremely difficult. Oh and blindness is a common side effect. And for added fun it’s an high explosive. Needless to say it’s not FDA approved.

Re: Ozempic drug supresses desire to smoke, drink and more?

#106

Post by TeMPOraL »

renewiltord wrote: post #102
lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

[flagged]

Not helpful. Drugs are drugs. Side effect happens. Sometimes not even related to the drug.

I don't know how you folks do it in the US, but I imagine there is a leaflet attached to the medication, and somewhere in it should be a phone number, physical address and/or an e-mail address of an institution that tracks drug side effects. If you're unlucky enough to have some weird reaction to a drug, it's good to let them know.

Re: Ozempic drug supresses desire to smoke, drink and more?

#107

Post by TylerE »

User23 wrote: post #104
ortusdux wrote: post #44

Earlier quoted context omitted.

>>due to the fact that eating now makes her sick. Reminds me of the first FDA approved weight loss drug, Alli, that basically just gastrointestinally punishes you if you eat more than a few grams of fat. https://en.wikipedia.org/wiki/Orlistat#Side_effects

My favorite fat loss drug along these lines is dinitrophenol. It is the true miracle fat burning drug. It interferes with cellular metabolism in such a way that the body just nonstop oxidizes fat. Fat mass loss in the order of a pound a day or more is entirely possible and some bodybuilders use it to get to a ludicrously low bodyfat percentage. Unfortunately oxidizing that much fat generates a lot of heat, so much th…

> And for added fun it’s an high explosive

Better not tell that to all the cardiac patients on nitroglycerin.

Re: Ozempic drug supresses desire to smoke, drink and more?

#108

Post by vrc »

lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

The risk of pancreatitis is also increased substantially [0]. And for people who may already be predisposed to pancreatitis but haven’t had an attack, severe pancreatitis has a 10-30% mortality rate [1]. But even mild acute pancreatitis will make you want to crawl out of your own skin in pain.

[0] https://www.hopkinsmedicine.org/news/media/releases/johns_ho...

[1] https://www.aafp.org/pubs/afp/issues/2007/0515/p1513.html

Re: Ozempic drug supresses desire to smoke, drink and more?

#109

Post by mastax »

glonq wrote: post #61

What happens when you reach your target weight with drugs like this? After having learned potentionally nothing about nutrition, exercise, and self-control, are you stuck on these meds for life out of fear of binge-eating back to your original weight? FWIW I'm on a hundred-pound roller coaster ride from 300lbs to 200lbs; currently ~215. I've learned a lot about discipline and sustainable habits along the way.

Presumably the dose can be altered such that for a given individual their appetite creates a caloric equilibrium at close to the target weight. I don't think this is something that is done currently.

The side effects of chronic use don't appear to be that significant and would need to be weighed against the side effects of chronic obesity.

Re: Ozempic drug supresses desire to smoke, drink and more?

#110

Post by rafaelero »

renewiltord wrote: post #102
lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

[flagged]

Right? For god sake folks, trust the randomized trials, not Internet nocebo screamers.
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