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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

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Re: Ozempic drug supresses desire to smoke, drink and more?

#91

Post by ex3ndr »

lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

Super weird since once you get thyroid problems, you have to drop this medication.

Re: Ozempic drug supresses desire to smoke, drink and more?

#92

Post by znpy »

ortusdux wrote: post #58
spondylosaurus wrote: post #52

Earlier quoted context omitted.

> The manual for Alli makes it clear that orlistat treatment involves aversion therapy, encouraging the user to associate eating fat with unpleasant treatment effects. Christ. This is like Crohn's disease in pill form. One too many teaspoons of olive oil and you're in for an unpleasant evening...

I remember grabbing a pamphlet when it was new and reading their recommendation to wear dark colored pants and bring a change of clothes to work.

Jesus Christ on a bike, that’s beyond dystopian, that’s completely f—-ked up.

Does the fda allow that?

Re: Ozempic drug supresses desire to smoke, drink and more?

#93

Post by aidenn0 »

op00to wrote: post #86
ortusdux wrote: post #58

Earlier quoted context omitted.

I remember grabbing a pamphlet when it was new and reading their recommendation to wear dark colored pants and bring a change of clothes to work.

[flagged]

I want to frame this comment as an example of (the generalized form of) Poe's law.

Re: Ozempic drug supresses desire to smoke, drink and more?

#94

Post by contravariant »

Avshalom wrote: post #87

"Semaglutide does not dull all pleasure, people taking the drug for weight loss told me. They could still enjoy a few bites of food or revel in finding the perfect dress; they just no longer went overboard. Anhedonia, or a general diminished ability to experience pleasure, also hasn’t shown up in cohorts of people who take the drug for diabetes, says Elisabet Jerlhag Holm, an addiction researcher at the University of…

I'm not sure it is pleasure driving people to go overboard. I'm pretty sure it is dissatisfaction that is driving excess. In which case a drug that means you're more easily satisfied is far from bleak.

If anything the opposite is far more bleak. Imagine if there was a drug that meant you're less easily satisfied, who on earth would want that?

Re: Ozempic drug supresses desire to smoke, drink and more?

#96

Post by op00to »

glonq wrote: post #61

What happens when you reach your target weight with drugs like this? After having learned potentionally nothing about nutrition, exercise, and self-control, are you stuck on these meds for life out of fear of binge-eating back to your original weight? FWIW I'm on a hundred-pound roller coaster ride from 300lbs to 200lbs; currently ~215. I've learned a lot about discipline and sustainable habits along the way.

What happens when someone who was previously deeply depressed but feels better goes off an antidepressant? They learn to handle life, or they return to the drug if further treatment is needed. It’s not a moral failing.

Re: Ozempic drug supresses desire to smoke, drink and more?

#97

Post by 015UUZn8aEvW »

mym1990 wrote: post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

>From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

This is true of every weight loss intervention: Weight Watchers, low-carb, keto, Whole 30, etc. Once people stop complying with them, they gain the weight back.

Most people don't realize how dismal the stats on long-term weight loss are. Almost no one maintains a substantial amount of weight loss for many years by following "just eat healthy and exercise" advice. The only intervention that does reliably work is bariatric surgery. The jury is still out on the new GLP drugs.

Re: Ozempic drug supresses desire to smoke, drink and more?

#98

Post by pixl97 »

throwaway5959 wrote: post #95

Wasn’t this the plot of the Firefly movie? It didn’t work out well for them.

I mean the opposite where we're fattening up ourselves like lambs for the slaughter isn't working out great either. We've had recent downward trend in longevity.

Re: Ozempic drug supresses desire to smoke, drink and more?

#99

Post by vrc »

ortusdux wrote: post #44
lumb63 wrote: post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

>>due to the fact that eating now makes her sick. Reminds me of the first FDA approved weight loss drug, Alli, that basically just gastrointestinally punishes you if you eat more than a few grams of fat. https://en.wikipedia.org/wiki/Orlistat#Side_effects

Never trust a fart on orlistat. The horror stories I’ve read of people soiling themselves after eating seemingly normal meals is nuts. On par with Olestra/Haribo sugar-free stories. Also it makes absorbing fat soluble vitamins a huge issue.

Re: Ozempic drug supresses desire to smoke, drink and more?

#100

Post by tetrep »

contravariant wrote: post #94
Avshalom wrote: post #87

"Semaglutide does not dull all pleasure, people taking the drug for weight loss told me. They could still enjoy a few bites of food or revel in finding the perfect dress; they just no longer went overboard. Anhedonia, or a general diminished ability to experience pleasure, also hasn’t shown up in cohorts of people who take the drug for diabetes, says Elisabet Jerlhag Holm, an addiction researcher at the University of…

I'm not sure it is pleasure driving people to go overboard. I'm pretty sure it is dissatisfaction that is driving excess. In which case a drug that means you're more easily satisfied is far from bleak. If anything the opposite is far more bleak. Imagine if there was a drug that meant you're less easily satisfied, who on earth would want that?

> If anything the opposite is far more bleak. Imagine if there was a drug that meant you're less easily satisfied, who on earth would want that?

That sounds like stimulants. You wouldn't be motivated to do things if you were satisfied, so any drugs that motivate people would seem to need to have to have such an effect.

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