My all-time favorite was GPSS (General Purpose Simulation System) which would simulate transactions in a model...think of cars arriving from four directions at a traffic light. You could tweak the car arrival times and the length of red/green lights and get different outputs for 'wait time'.
I loved it so much, I asked my professor if there were good opportunities for a career using GPSS. He answered 'no' (LOL) and so I never pursued it.