361–370 of 406 posts
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I think you misunderstood something in the comment I replied to, which stated: > Not only that, but if people can improve their condition with three treatments to the point that they no longer need their daily dose of anti-depressant or ADHD medication (or alcohol / opiates / etc. for the self-medicating cohort) then overall drug consumption will drop steeply. The key thing here is the claim being made that three dos…
How would you know if you didn't at least try? The claim that the only way that ADHD symptoms can be managed successfully is with daily use of a fairly powerful stimulant-class drug seems equally implausible.
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People seem to think they can just take a load of mushies and it can solve all lives problems. The great art requires a lot of hard heart work and suffering.
Well, its like people who describe Ketamine therapy. The process itself can be deeply traumatizing, even if the after-effects make up for it. I've heard it described as deep hallucinations, often touching on dark places in your psyche, while you can't get up or do much or get away from it. On the plus side, it can make you face some difficult internal issues, but on the downside, not everyone actually responds well t…
I cannot imagine doing this substance without someone else there. There were multiple times I simply needed a hand to hold as I was… descending, and my second trip was a “bad” one. The therapist was absolutely critical for helping me frame what happened in a positive light.
Contrary data point to encourage caution with MDMA: MDMA can reset your dopamine baseline much lower. That is, after you come down, you may feel depressed, and it may be hard to climb out of that depression for a while. Use caution please.
I think you mean serotonin. MDMA causes greater release of serotonin and norepinephrine than of dopamine, and dopamine resets to baseline much faster than serotonin. > MDMA-exposed primates showed reduced numbers of serotonergic neurons 7 years later, indicating that some of MDMA’s effect on the brain can be long lasting. > Low serotonin is associated with poor memory and depressed mood, thus these findings are consi…
Fwiw, MDMA affects 3 neurotransmitters: serotonin, dopamine, and norepinephrine.
Having a low dopamine baseline can also be really bad tho! Hard to get motivated...
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> What your post comes across as, to me anyway, is that you want drugs to be a bad thing. I am curious how you could interpret that.
> I wish more people spoke about their negative experiences with psychedelics. that > It's a sobering and necessary counterpoint... and that.
One thing that people didn't want to talk about with the cannabis legalization boom was how common paranoid schizophrenia is. My step-father has marijuana-induced paranoid schizophrenia, I have a few other friends also diagnosed with the same thing. For all the good that it has done for x demographics, it has damaged y demographics irreparably. A future of powerful and debilitating prescription drugs to treat their schizophrenia is what they have to look forward to now, they are objectively worse off for it and classified as legally disabled.
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As studies continue, it seems that a key component is a safe and therapeutic environment and a trained guide who can help the person navigate what they experience. People most often get in trouble when they bring a recreational drug mindset, or are predisposed to certain conditions, or have not worked with a therapist to have foundational tools to manage the experience. The risks are absolutely real and should not be…
Interestingly, my recent bad experience was in what I expected to be the safest and most therapeutic environment available to me. What I discovered instead was an irrational culture with an immature fascination for shamanism. My individual experiences, informed by my research, were more beneficial (and cheaper as well). Knowing the topic and a trip-sitter you know might prove a better choice than trusting self-procla…
Almost 350 comments, none of which mention how dangerous MDMA is, especially to the kidneys, the heart, and the serotonergic neurons of the brain?
Everything in medicine has a risk factor that must be weighed against the benefits.
Can someone share any relevant experience with this? Best would be if you did it properly under supervision of clinical professional, or if you are a professional here, by any chance. Doesn’t matter if it’s US or not.