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New insights into why aspirin works so well

eurekalert.org

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Re: New insights into why aspirin works so well

#221

Post by atombender »

mistrial9 wrote: post #216
atombender wrote: post #168

Earlier quoted context omitted.

This might surprise you, but we don't actually fully understand how most drugs work. Not just common OTC drugs, either, but also complex synthetic drugs used for things like autoimmune disorders, preventing organ rejection, and so on. Not just drugs that have been in use since the inception of modern medicine, but also about brand new drugs. Often we have some idea how they work and what the internal end result appea…

> Modern medicine is optimized for end results except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

Which ones?

Re: New insights into why aspirin works so well

#222

Post by fundatus »

mistrial9 wrote: post #216
atombender wrote: post #168

Earlier quoted context omitted.

This might surprise you, but we don't actually fully understand how most drugs work. Not just common OTC drugs, either, but also complex synthetic drugs used for things like autoimmune disorders, preventing organ rejection, and so on. Not just drugs that have been in use since the inception of modern medicine, but also about brand new drugs. Often we have some idea how they work and what the internal end result appea…

> Modern medicine is optimized for end results except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

> except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

Except they are not being replaced? Just like in the good old days™ you can still get out and collect the herbs you're looking for. It's just that nowadays we know that component X of a herbal remedy actually does the job so you just buy that in tablet form (or whatever) instead eating of the whole thing.

Re: New insights into why aspirin works so well

#223

Post by selfmodruntime »

Fragoel2 wrote: post #185
selfmodruntime wrote: post #128

Earlier quoted context omitted.

No. Science has all along been testing if something works and then finding out why. Often the „why“ is orders of magnitudes harder to find out than the „if“. For example, we can observe how the brain functions in some instances, but why it works like does will elude us perhaps forever. Highly complex systems like the inner biomechanical workings of our brains are essentially a black box.

For an example in CS, we currently use machine-learning algorithms that work very well in practice. However, why they work so well is still unclear in many cases (although we are making progress).

I find it fascinating that describing an automated learning process is so much easier than manually teaching. Once trained, looking inside a model to gather information about how it comes up with an answer to a question is somewhat similar to doing exactly that with a real brain.

Re: New insights into why aspirin works so well

#224

Post by neom »

thenerdhead wrote: post #209
IE6 wrote: post #207

Earlier quoted context omitted.

Do you have any good literature on Aspirin and LC? Not a doubter, actually I have LC myself.

I do not. I have my personal anecdote and experiences with common painkillers and LC. I've had it since January 2021 so there wasn't really anything known when I started taking aspirin outside of the many years of research as mentioned in OP's article. Here's my experience so far. https://jondouglas.dev/long-covid/ I've swapped aspirin about a year in for nattokinase and have noticed much better management. I still t…

Just adding a +1 for long covid and aspirin, aspirin + CBD cream (Momma Canna Cream, I think only available in Canada) was a game changer for me! I rubbed the CBD cream into my head and neck and took bayer "daily" low dose aspirin till I started to feel normal again (brain fog cleared).

Re: New insights into why aspirin works so well

#226

Post by elteto »

mistrial9 wrote: post #216
atombender wrote: post #168

Earlier quoted context omitted.

This might surprise you, but we don't actually fully understand how most drugs work. Not just common OTC drugs, either, but also complex synthetic drugs used for things like autoimmune disorders, preventing organ rejection, and so on. Not just drugs that have been in use since the inception of modern medicine, but also about brand new drugs. Often we have some idea how they work and what the internal end result appea…

> Modern medicine is optimized for end results except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

If anything the pseudo-scientific, barely regulated industry of "herbal" and "natural" remedies and supplements is booming right now and has been for two decades at least. Nobody is replacing anything, you can buy whatever you want.

Re: New insights into why aspirin works so well

#227

Post by mistrial9 »

fundatus wrote: post #222
mistrial9 wrote: post #216

Earlier quoted context omitted.

> Modern medicine is optimized for end results except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

> except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY Except they are not being replaced? Just like in the good old days™ you can still get out and collect the herbs you're looking for. It's just that nowadays we know that component X of a herbal remedy actually does the job so you just buy that in tablet form (or whatever) instead eating of the whole thing.

> get out and collect the herbs you're looking for.

on the small chance that you are not being sarcastic.. Our city here has >300,000 residents.. and most cities nearby are paved. Where do the herbs come from ?

Re: New insights into why aspirin works so well

#228

Post by mistrial9 »

elteto wrote: post #226
mistrial9 wrote: post #216

Earlier quoted context omitted.

> Modern medicine is optimized for end results except thousands of common herbal remedies are replaced by patent medicine with legal controls, because $MONEY

If anything the pseudo-scientific, barely regulated industry of "herbal" and "natural" remedies and supplements is booming right now and has been for two decades at least. Nobody is replacing anything, you can buy whatever you want.

I dont think you know the history of the regulated drug industry, or computational pharmacology in California.

Re: New insights into why aspirin works so well

#229

Post by elteto »

mistrial9 wrote: post #228
elteto wrote: post #226

Earlier quoted context omitted.

If anything the pseudo-scientific, barely regulated industry of "herbal" and "natural" remedies and supplements is booming right now and has been for two decades at least. Nobody is replacing anything, you can buy whatever you want.

I dont think you know the history of the regulated drug industry, or computational pharmacology in California.

Do you?

Re: New insights into why aspirin works so well

#230

Post by ck2 »

IE6 wrote: post #207
thenerdhead wrote: post #171

Aspirin has been a life changer for long Covid. The other painkillers make symptoms 10x worse. Many people wonder if aspirin anti platelet/blood thinning capabilities is helping breakup microclots which brings relief. There’s also a thing called nattokinase that apparently has similar properties to aspirin and is being studied for heart disease. It has been shown to break down blood clots and even degrade the spike p…

Do you have any good literature on Aspirin and LC? Not a doubter, actually I have LC myself.

The micro-clots in covid and long-covid are fibrin clots, not platelet clots.

There is endless documentation and photos of this, it looks like tangled spaghetti.

Every report of aspirin vs covid is wishful thinking, it does nothing.

The amount of misinformation with covid and long-covid is astounding.

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