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Earlier quoted context omitted.
There are other, even OTC, painkiller medications that might be worth trying. Diclofenac (Voltaren/Flector etc) or Metamizole (variously banned, prescription-only or OTC seemingly random around the world) for example, and then there some newer non-opioid painkillers maybe worth trying but those are mostly prescription only.
Also meloxicam, a higher potency anti-inflammatory tolerated by the stomach better than other options
I imagine different people tolerate different anti-inflammatory over-the-counter drugs differently. Side effects of overuse are significant however and include liver, kidney, and gastrointestinal damage (acetaminophen, ibuprofen and aspirin respectively I think with some crossover effects). Use judiciously, and only take regularly under a doctor's supervision as side effects can be minimized with additional drugs whi…
Ibuprofen and aspirin can both reliably produce internal gastrointestinal bleeds after a single dose in people with underlying digestive diseases. Over enough time with constant usage, they'll cause that in anybody.
Earlier quoted context omitted.
If we could reliably show that ground rhino horns and tiger penises work, we'd be using them, or finding an easily mass produced derivatives.
Same as we did with willow bark and ended up with aspirin we have today. History of aspirin: https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.14520
When you say in 2023 that they have "new insights" as to why a common over the counter drug works it really doesn't instill great confidence in pharma. Seems like we're still grinding up rhino horns and tiger penis and hoping for the best outcome, just that we do it with extensive testing now so we get a statistically acceptable outcome viable for marketing.
Honestly, aspirin is really closer to "grinding up rhino horns" than to complex pharmaceuticals you have to make in a lab. It's literally "drink this tea made from willow bark" except we got better at isolating the active components and finding other ways to produce them and more reliably measuring the dosage. The difference is that empirical studies have demonstrated the effect of "willow bark tea" and the lack of a…
When you say in 2023 that they have "new insights" as to why a common over the counter drug works it really doesn't instill great confidence in pharma. Seems like we're still grinding up rhino horns and tiger penis and hoping for the best outcome, just that we do it with extensive testing now so we get a statistically acceptable outcome viable for marketing.
When you say in 2023 that they have "new insights" as to why a common over the counter drug works it really doesn't instill great confidence in pharma. Seems like we're still grinding up rhino horns and tiger penis and hoping for the best outcome, just that we do it with extensive testing now so we get a statistically acceptable outcome viable for marketing.
Aspirin has been a life changer for long Covid. The other painkillers make symptoms 10x worse. Many people wonder if aspirin anti platelet/blood thinning capabilities is helping breakup microclots which brings relief. There’s also a thing called nattokinase that apparently has similar properties to aspirin and is being studied for heart disease. It has been shown to break down blood clots and even degrade the spike p…
"it can cause detrimental side effects such as internal bleeding and organ damage" NSAIDs are also ototoxic, meaning that they cause hearing damage.
It thankfully went away after a day or so after I (immediately) stopped and I don't seem to have suffered any permanent damage that I know of, but it taught me to not fuck around with NSAIDs.
Aspirin has been a life changer for long Covid. The other painkillers make symptoms 10x worse. Many people wonder if aspirin anti platelet/blood thinning capabilities is helping breakup microclots which brings relief. There’s also a thing called nattokinase that apparently has similar properties to aspirin and is being studied for heart disease. It has been shown to break down blood clots and even degrade the spike p…
Do you have any good literature on Aspirin and LC? Not a doubter, actually I have LC myself.
https://jondouglas.dev/long-covid/
I've swapped aspirin about a year in for nattokinase and have noticed much better management. I still take aspirin here and there, but NK is doing its job.
https://pubmed.ncbi.nlm.nih.gov/36080170/
https://www.webmd.com/covid/news/20221207/microclots-may-exp...
https://pharmd.substack.com/p/frequency-asked-questions-natt...
Hope that helps you.
EDIT: I heard about triple anticoagulant therapy but never realized aspirin is included in it. Check out this study here: https://www.researchsquare.com/article/rs-2697680/v1
"it can cause detrimental side effects such as internal bleeding and organ damage" NSAIDs are also ototoxic, meaning that they cause hearing damage.
Yeah, for all the hype about opioids being bad, these 'safe' drugs are way more dangerous than commonly purported. Acetaminophen is especially bad because the toxicity threshold is only slightly above the therapeutic dose. That is why they have to put so many warnings on this 'safe' drug. Yet let's blame opioids. https://en.wikipedia.org/wiki/Therapeutic_index