As a VC, I would never fund any of these. How about these twenty-five ideas for starters.
1. Combine local and real-time. (Google isn't)
2. Combine the cloud with viral marketing (Amazon isn't)
3. Disrupt green with crowd-sourcing. (Power companies aren't).
4. Curate blogging (the "blogosphere" is so wide it becomes meaningless. Get the stratosphere of the blogosphere).
5. post-pc disruption. (Fingerpaint for iPhone - 1 guy, VC-ready company. needed a mac to develop. give an Indian with no mac, no pc, nothing BUT an iPhone enough tools to disrupt post-pc)
6. scale photos. Flickr doesn't.
7. the Google of Facebook. (G+ is the Facebook of Google. Where's the Google of facebook?)
8. empower html5. (Where's the Adobe of HTML 5?)
9. the skype of documents. (Google Docs isn't it)
10. the apple of automobiles. ("iPod integration"? Give me a 'brake').
11. bring the cloud to ultramobiles. ("ultrabooks" are a joke, and the cloud is too big. Find a way to make ultrabooks/macbook airs the macs of iOS)
12. the reddit of shopping. (eBay is not it).
13. disrupt ad platforms, virally. People are sick of signing in and getting information collected (Google starting to suck)
14. one word: Firefox. (Firefox isn't it).
15. one word: Office. (Office isn't it).
16. one word: ultramobile. (MacBook isn't).
17. one word: ultralite mobile. (iOS isn't it)
18. one word: TechCrunch (TechCrunch isn't it)
19. one word: Banking (Banking isn't it)
20. one word: Trending (Analytics isn't it)
21. one word: Microblogging (Twitter isn't it)
22. one word: Dating (plenty-of-fish isn't)
23. one word: Family disruption, aka Whores. (craigslist isn't)
24. one word: disrupt paradigms. (YC isn't).
25. one word: cloud. (the cloud isn't.)
what is this, some kind of a joke? Can you even tell anymore. Disrupt this.