Live data from Hacker News

To ensure vaccines work properly, men should get a good night’s sleep

economist.com

41–50 of 52 posts

Re: To ensure vaccines work properly, men should get a good night’s sleep

#43

Earlier quoted context omitted.

Wait, hormone replacement therapies in women? I don’t understand this one. If we are referring to transgender women, I think they’re like less than 1% of the population or something so it doesn’t make sense to rule out all women for an outlier. If we are referring to menopausal women, I don’t believe hormone replacement for menopause is very popular (I heard it causes health problems??). Also don’t men also get hormo…

Hormone replacement is common treatment for menopause, but indeed for some women it’s not an option due to particularly bad side effects. Men don’t typically need hormone replacement in old age, testosterone production rarely drops much, if at all. It’s why we grow bald, after all.

Testosterone absolutely declines in men, but it's gradual over your lifetime rather than a rapid change like the menopause. Typically, T peaks in your late teens, then declines around 1-2% per year for the rest of your life.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#44

Earlier quoted context omitted.

I was turned off before the part about women. Im too tired for more lectures about how im supposed to spend more time being less tired. Sunday morning. The boss needs something done by 0900 and then i have a conference call at 1000 ( a "coms check" ahead of the real call monday morning). So it's time to stop reading about sleep and do the thing that pays the bills.

What company in tech has mandatory Sunday work? Seems a little extreme. I'm guessing most companies don't have this so the best option is to work for one of them.

Military. We have an important teleconference monday morning with some new people using new systems (0500 local, noon in europe). That means we need to do a coms check today (sunday) if we want to have enough time to iron out any details. Sunday is also a better time for such things as the systems/rooms are not already booked for other things. So we can run late without having to bump other groups off of equipment/networks/rooms etc. But there are lots of civilian tech jobs that require work on the weekends too. Data centers do not shut down on weekends, nor do the millions of network connections that tie everything together.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#45

Earlier quoted context omitted.

Hormone replacement is common treatment for menopause, but indeed for some women it’s not an option due to particularly bad side effects. Men don’t typically need hormone replacement in old age, testosterone production rarely drops much, if at all. It’s why we grow bald, after all.

Testosterone absolutely declines in men, but it's gradual over your lifetime rather than a rapid change like the menopause. Typically, T peaks in your late teens, then declines around 1-2% per year for the rest of your life.

Until you qualify as "low T". They the docs prescribe you enough testosterone supplement that to you get bored with golf and start power lifting. You ain't "juicing" if your doctor is the one selling the pills.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#46
post #39

Earlier quoted context omitted.

Perhaps it was a reference to birth control.

The researchers[0] listed that with an "and" rather than a "for example". > varying stages of the menstrual cycle, contraception and hormone-replacement therapies [0] or at least the @JusticeJuice quotation, as the free version of the article doesn't contain the link to the actual research paper…

https://www.cell.com/current-biology/fulltext/S0960-9822(23)...

From the paper's discussion

> Given that sex impacts the response to vaccine,9,25 we calculated separate overall ES for men and women. When sleep was assessed objectively, the pooled ES was large and highly significant for men, whereas it was smaller and not significant for women, likely due to the wide variations in sex hormone levels according to phase of the menstrual cycle, use of hormonal contraception, menopausal status, and use of hormonal replacement in post-menopausal women.25 None of the studies included in our meta-analysis controlled for these known hormonal modulators of immune function.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#47
post #39

Earlier quoted context omitted.

The researchers[0] listed that with an "and" rather than a "for example". > varying stages of the menstrual cycle, contraception and hormone-replacement therapies [0] or at least the @JusticeJuice quotation, as the free version of the article doesn't contain the link to the actual research paper…

https://www.cell.com/current-biology/fulltext/S0960-9822(23)... From the paper's discussion > Given that sex impacts the response to vaccine,9,25 we calculated separate overall ES for men and women. When sleep was assessed objectively, the pooled ES was large and highly significant for men, whereas it was smaller and not significant for women, likely due to the wide variations in sex hormone levels according to phase…

Thanks! :)

Re: To ensure vaccines work properly, men should get a good night’s sleep

#48

Earlier quoted context omitted.

Hormone replacement is common treatment for menopause, but indeed for some women it’s not an option due to particularly bad side effects. Men don’t typically need hormone replacement in old age, testosterone production rarely drops much, if at all. It’s why we grow bald, after all.

Testosterone absolutely declines in men, but it's gradual over your lifetime rather than a rapid change like the menopause. Typically, T peaks in your late teens, then declines around 1-2% per year for the rest of your life.

Sure. It’s also comparatively small drop that rarely needs treatment.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#49
post #11
post #6

Earlier quoted context omitted.

[flagged]

HN is a great resource for exchanging ideas, knowledge, and valuable insights. I believe we can keep it that way by fostering a social and friendly atmosphere.

[flagged]
Post reply on HN