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To ensure vaccines work properly, men should get a good night’s sleep

economist.com

11–20 of 52 posts

Re: To ensure vaccines work properly, men should get a good night’s sleep

#11
post #6

Very interesting. There is some evidence (to my limited knowledge, please correct me if I'm wrong) that testosterone has some immune-inhibiting properties and women's immune systems are more reactive. Can this simply be a case of men's immune systems reacting to the antibodies at a slower pace?

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Re: To ensure vaccines work properly, men should get a good night’s sleep

#12
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

It’s the data that shows the situation for women is less clear. This is good advice: when getting vaccinated make sure to get a good night sleep. Why the outrage?

Re: To ensure vaccines work properly, men should get a good night’s sleep

#13
post #12
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

It’s the data that shows the situation for women is less clear. This is good advice: when getting vaccinated make sure to get a good night sleep. Why the outrage?

Did you read the paragraph about women? It says there was too much noise in data, they could not measure positive effect of sleep! What conclusions medical professional would derive from that?

Secondly I really do not like the overall tone of the article.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#14
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

It's certainly believable their immune systems don't work exactly the same way. Men usually feel sicker when they get ill as well IIRC.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#15

Very interesting. There is some evidence (to my limited knowledge, please correct me if I'm wrong) that testosterone has some immune-inhibiting properties and women's immune systems are more reactive. Can this simply be a case of men's immune systems reacting to the antibodies at a slower pace?

Women are more prone to autoimmune diseases as well.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#16
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

My guess is that this study is a load of nonsense, they are probably just picking up a signal for how generally healthy a population is rather than any real difference in vaccination efficacy. We know healthy people fight the virus better, how do you effectively remove that from the fighting the virus better by vaccination? Having slept well sounds like something people who would fight COVID better anyway would do. Does anyone have a link to the paper so I can see if they try to factor for these?

Re: To ensure vaccines work properly, men should get a good night’s sleep

#17
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

Hackernews provides a cool space on the Internet at this brief moment in time. It's wonderful randomly seeing passionate voices that are experts in their field speak up in comments.

Your input is appreciated, but I hope this space doesn't help breed hatred.

It's tough in today's world resisting the urge to take down others when we're suffering. But we all lose when we alienate those others who can bring intellectual sparks of joy into this world. Every voice matters, however brief it is.

Re: To ensure vaccines work properly, men should get a good night’s sleep

#18
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

> That does not apply to women, because they are gorgeous, and we should not tell them what to do.

I am baffled how you took that away from the article. Did we read the same thing? This is what they had to say about the results for women.

> As for why the results in women were not significant, Dr Spiegel and her colleagues theorise that sleep affects female response to vaccines too but that hormone interference, driven by varying stages of the menstrual cycle, contraception and hormone-replacement therapies, is probably altering immune response in profound and unknown ways that throw off the results. It is a subject area that urgently needs more attention, argue the researchers.

???

Re: To ensure vaccines work properly, men should get a good night’s sleep

#19
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

> That does not apply to women, because they are gorgeous, and we should not tell them what to do. I am baffled how you took that away from the article. Did we read the same thing? This is what they had to say about the results for women. > As for why the results in women were not significant, Dr Spiegel and her colleagues theorise that sleep affects female response to vaccines too but that hormone interference, driv…

[deleted]

Re: To ensure vaccines work properly, men should get a good night’s sleep

#20
post #7

Maybe they should also exercise, eat healthy, not be obese, avoid stress... All of that may boost vaccine effect! That does not apply to women, because they are gorgeous, and we should not tell them what to do. What a garbage!

My guess is that this study is a load of nonsense, they are probably just picking up a signal for how generally healthy a population is rather than any real difference in vaccination efficacy. We know healthy people fight the virus better, how do you effectively remove that from the fighting the virus better by vaccination? Having slept well sounds like something people who would fight COVID better anyway would do. D…

https://www.cell.com/current-biology/fulltext/S0960-9822(23)...

AFAIK, it's established that white blood cells are mainly produced when sleeping. So seems reasonable that lower white blood cell count makes vaccines less effective - in the same way vaccination for people with weaker immune systems are less effective.

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