My priority in the United States:
1. Children's Hospitals (St. Judes, Ronald McDonalds house)
2. Animal Shelters (local is best)
3. Veterans
4. Teaching/Education Institutions
5. Climate Emissions (Stripe)
Can't tell you that I'm donating thousands of dollars or anything like that, but usually if it asks for a donation at the end, I normally "round up" or donate a dollar.
For children's hospitals, you want to look at what they are doing for not only the children, but the families as well. As far as I know, St. Judes doesn't bill the families. I also listed Ronalds McDonald's house because of what happened to my sister when she was 21, getting hit by a drunk driver, and as a result, was with a fractured skull, fractured ribs, and a lifetime of seizures. The hospital had put her in the children's ward and there was a "Ronald's McDonalds House" which was a room in the hospital with food, drinks, blankets, and beds that my family was using so we could stay close to my sister when visiting hours were over.
To animal shelters, I don't donate money, but I do donate blankets and towels or toys or even pet food and if I find myself not using a cage or a travel bag I bought, I'm dropping that off as well. Anything and everything to make sure an animal doesn't have to sleep on a cold floor and that they at least have something going with them to their new home.
Almost all the males in my family or someone I know who is close to me is a Veteran of some war. World War II, Korean War, Vietnam War, Gulf War, Afghanistan War, and Iraq war. I'm currently taking care of my "second" grandfather, who served under JFK during the Bay of Pigs Cuban Missile Crisis. He's got dementia and colon cancer at 86... but I'm trying to keep him alive by giving him the best life he has ever had. I hope someday I have someone to spoil me like I do for him.
Teaching/Education institutions are often charity to fund educational programs in poor communities that lack the resources of desks, computers, Internet, etc., and childhood education is the foundation of the future of any civilization.
And finally, although I'm not stating that climate change is going to kill us, as humans are pretty adaptable, as the world does see changes over time, I do firmly believe that human impact has affected the climate greatly. There's no way you can run all these factories that emit pollution into the air, have all these cars, planes, and ships burning fossil fuels, and say that isn't affecting the environment. I do not think it will kill humans any time soon, but it does impact animal life and the Earth itself. Affecting animal life affects nature which can't be good for any species.
I don't think Stripe is buying "climate credits" which just sounds like a bullshit scam to me, but what Stripe does is fund "climate projects" that are trying to offset carbon emissions that may be contributing towards climate change, and that's why for any project I create, I donate 1% of the proceeds to their efforts. https://stripe.com/climate
You should always have a charity that you are willing to donate to meaning you've done your research and you know at least 80% plus of your dollar is going to the actual cause. "Administration fees" are always going to be there because there are people who have to get paid to keep the organization running, structured, and also for their outreach/advertising costs too, so that is expected.