Project Orion is a really bad idea. I guess it could be a good idea in specific situation where have to get a lot of mass off the planet and don't care about the effects. Problem one is that detonating a series of nuclear bombs in the atmosphere. The first couple are close to the ground and produce local fallout, the higher ones produce global fallout. Problem two is that detonating nuclear bombs in space causes EMP.…
Launching from lunar orbit would obviate EMP and terrestrial radiation concerns. But those are the least of the concerns.
The other problem is that nuclear weapons are expensive. Something like Davy Crockett is 2kg of plutonium, and mid-sized Orion would use 800 to get to orbit. Plutonium is $4000/g which means $6.4 billion to launch Orion. Orion that puts 1600t in orbit. Or 10 Starships which is less as disposable rockets and way less if reuasable.