I have done many things, but I went from IT into being a Technical Director for animation. In my case my income went up, cause reasons, but I think for many folks in pure tech it would be a significant cut. But my coworkers are awesome, my work is fun, I'm pure remote from the shore of Lake Winnipeg. Life is great.
I can't generalize my experience onto the entire labour market, but from what I can see, the whole "gaps in your record" matters a lot less now than it did. My record is abysmal from that perspective, again because reasons, but in animation at least that really doesn't matter. I'm one of many autodidacts here.